James Glenn Krueger , MD, PhD

James Glenn Krueger

Corresponding Member of the Division of Mathematics and Natural Sciences abroad since 2023

  • The Rockefeller University

Contact:

Orcid-ID:

0000-0002-3775-1778

Research Areas:

  • Health Sciences

Profile:

CV/Website

Selected Memberships:

  • American Academy of Dermatology (AAD)
  • Society for Investigative Dermatology (SID)
  • American Society for Clinical Investigation (ASCI)
  • Association of American Physicians (AAP)
  • National Psoriasis Foundation (NPF)
  • American Dermatology Association (ADA)
  • International Psoriasis Council (IPC)

Selected Prizes:

  • ACTS Distinguished Investigator: Translation from Early Clinical Use to Applicability for Widespread Clinical Practice Award
  • Van Scott Award for Innovative Therapy of the Skin and Frost Leadership Lecture – American Academy of Dermatology
  • Farber Award and Lecture – Society of Investigative Dermatology
  • Astellas Award in Public Health – American Academy of Dermatology
  • R.K. Schachter Lectureship Award

Selected Publications:

  • Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyteresponse pathways. Nograles KE, Zaba LC, Guttman-Yassky E, Fuentes-Duculan J, Suárez-Fariñas M, Cardinale I, Khatcherian A, Gonzalez J, Pierson KC, White TR, Pensabene C, Coats I, Novitskaya I, Lowes MA, Krueger JG. Br J Dermatol. 2008 Nov;159(5):1092-102. PMID: 18684158.
  • Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including theactivation of keratinocytes, dendritic cells, and endothelial cells. Abrams JR1, Kelley SL, Hayes E,Kikuchi T, Brown MJ, Kang S, Lebwohl MG, Guzzo CA, Jegasothy BV, Linsley PS, Krueger JG. J ExpMed. 2000 Sep 4;192(5):681-94. PMID: 10974034.
  • Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. Lee E1, Trepicchio WL, Oestreicher JL, Pittman D, Wang F, Chamian F, Dhodapkar M, Krueger JG. J Exp Med. 2004 Jan 5;199(1):125-30. PMID: 14707118.
  • Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells. Lowes MA, Kikuchi T, Fuentes-Duculan J, Cardinale I, Zaba LC, Haider AS, Bowman EP, Krueger JG. J Invest Dermatol. 2008 May;128(5):1207-11. PMID: 18200064.
  • Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis. Gottlieb SL, Gilleaudeau P, Johnson R, Estes L, Woodworth TG, Gottlieb AB, Krueger JG. Nat Med. 1995 May;1(5):442-7. PMID: 7585092.