Prof. Dr. rer. nat.

Jürgen Knoblich

Jürgen Knoblich

Full Member of the Division of Mathematics and the Natural Sciences since 2013

Contact:

Research Areas:

  • Biology
  • Developmental biology
  • Genetics
  • Molecular biology
  • Stem cell research
  • Cell biology

Profile:

CV/Website

Publications:

Website

Selected Memberships:

  • European Molecular Biology Organization EMBO
  • Academia Europaea
  • International Society for Stem Cell Research ISSCR, board of directors
  • American Society for Cell Biology ASCB
  • EMBO council, elected member
  • Scientific Advisory Board, Cancer Stem Cell Network, Deutsche Krebshilfe
  • Päpstliche Akademie der Wissenschaften

Selected Prizes:

  • Wittgenstein-Preis des Wissenschaftsfonds FWF
  • ERC Advanced Grant
  • Erwin Schrödinger-Preis der ÖAW
  • EMBO Young Investigator Award
  • Early Career Award, European Life Scientist Organization

Selected Publications:

  • Lancaster, M. A., Renner, M., Martin, C. A., Wenzel, D., Bicknell, L. S., Hurles, M. E., Homfray, T., Penninger, J. M., Jackson, A. P., and Knoblich, J. A. (2013). Cerebral organoids model human brain development and microcephaly. Nature 501, 373-379..
  • Eroglu, E., Burkard, T. R., Jiang, Y., Saini, N., Homem, C. C., Reichert, H., and Knoblich, J. A. (2014). SWI/SNF Complex Prevents Lineage Reversion and Induces Temporal Patterning in Neural Stem Cells. Cell 156, 1259-1273..
  • Homem, C. C., Steinmann, V., Burkard, T. R., Jais, A., Esterbauer, H., and Knoblich, J. A. (2014). Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells. Cell 158, 874-888..
  • Bonnay F., Veloso A., Steinmann V., Köcher T., Abdusselamoglu M.D., Bajaj S., Rivelles E., Landskron L., Esterbauer H., Zinzen R.P. and Knoblich J.A. (2020). Oxidative metabolism drives immortalization of neural stem cells during tumorigenesis. Cell 182(6), 1490-1507..
  • Esk C., Lindenhofer D., Haendeler S., Wester R.A., Pflug F., Schroeder B., Bagley J.A., Elling U., Zuber J., von Haeseler A., Knoblich J.A. (2020) A human tissue screen identifies a regulator of ER secretion as a brain-size determinant. Science 370(6519), 935-941..