
How to attend
To attend the talk sessions in ZOOM, go to our SY-Stem EVENTEE website and click on the talk you would like to see.
Once you are in the ZOOM session, you can simply stay there for all subsequent calls.
https://eventee.co/event/13277
Note: Only invited and registred attendees can view the talks. Create an account with the email address that you used to register for SY-Stem!
All times are indicated in Central European Time (CET)
WEDNESDAY 03.03.2021
13:00 Welcome and introduction
PLURIPOTENCY, EARLY DEVELOPMENT & GASTRULATION
CHAIR: Sasha MENDJAN
13:15 Cantas Alev (Kyoto University)
Towards reconstituting human somitogenesis in vitro
13:45 Graziano Martello (University of Padua)
Identification of novel regulators of pluripotency in human cells
14:15 Ruth Hornbachner (Medical University Vienna)
MSX2 cooperates with SWI/SNF complex to safeguard syncytiotrophoblast fate of human trophoblast stem cells
14:35 Alejandro Aguilera Castrejon (Weizmann Institute of Science)
Ex utero Development of Mouse Embryos from Pre-Gastrulation to Advanced Organogenesis
14:55 Networking break: join us on REMO
CHAIR: Nicolas RIVRON
16:05 Silvia Santos (The Francis Crick Institute)
Decoding cellular signals during cellular transitions
16:25 Emiel van Genderen (Erasmus MC Rotterdam)
Linking morphogenesis and differentiation: a novel embryonic pluripotent state in between naïve and primed pluripotency
16:45 Christa Buecker (Max Perutz Labs)
Reshaping of the transcriptional and regulatory landscape during the exit from naïve pluripotency
ORGANOGENESIS
17:15 Sasha Mendjan (IMBA)
Cardioids reveal self-organizing principles of human cardiogenesis
17:45 break
CHAIR: Uli ELLING
18:00 Keynote lecture: Amy Wagers (Harvard Stem Cell Institute)
In vivo gene editing in tissues and tissue stem cells
19:00 Networking: join us on REMO
THURSDAY 04.03.2021
ORGANOGENESIS
CHAIR: Elly TANAKA
13:00 Miki Ebisuya (EMBL Barcelona)
Human Time vs. Mouse Time with Recapitulated in vitro Systems
13:30 Grayson Camp (Institute of Molecular and Clinical Ophthalmology Basel)
Human cerebral organoid development through the lens of single-cell genomics
14:00 Yekaterina Miroshnikova (Helsinki Institute of Life Science)
Heterochromatin-driven nuclear softening protects the genome against mechanical stress-induced damage
14:20 Denise Serra (Friedrich Miescher Institute for Biomedical Research)
Self-organization and symmetry breaking in intestinal organoid development
14:40 Networking break: join us on REMO
CHAIR: Juergen KNOBLICH
15:50 Jens Puschhof (Hubrecht Institute)
Organoids & Toxins - from snakebite to DNA-damaging bacteria
16:10 Georg Busslinger (Research Center for Molecular Medicine)
Human gastrointestinal epithelia of the esophagus, stomach and duodenum resolved at single-cell resolution
DISEASE
CHAIR: Uli ELLING
16:30 Meritxell Huch (Max Planck Institute of Molecular Cell Biology and Genetics)
Unveiling liver regeneration and disease mechanisms using organoid cultures
17:00 Abel Vertesy (IMBA)
Improved cell type resolution in cortical organoids by identification and removal of in-vitro stress
17:20 break
17:40 Jinwook Choi (Wellcome-MRC Cambridge Stem Cell Institute)
Inflammation shapes the lung regeneration
18:00 Kim Jensen (BRIC / University of Copenhagen)
At the origin of intestinal epithelial stem cells
18:30 Networking: join us on REMO
Friday 05.03.2021
DISEASE
CHAIR: Noelia URBAN
13:00 Florian Merkle (University of Cambridge)
Modelling obesity with human hypothalamic neurons
13:30 Gerald Schwank (ETH Zurich)
Translational genome editing: From ex vivo to in vivo
14:00 Alba Tristán-Noguero (Fundació Sant Joan de Déu)
Stem Cell Modeling of Tyrosine Hydroxylase Deficiency Recapituales Patient Phenotypes and Reveals Altered Neuronal Morphology
14:20 Enzo Poirier (The Francis Crick Institute)
A novel isoform of Dicer protects mammalian stem cells against RNA viruses
14:40 Networking break: join us on REMO
CHAIR: Uli ELLING
15:50 Karl Köhler (Boston Children’s Hospital/Harvard Medical School)
Sensory organoids for modeling development and disease
16:20 Alice Rossi (King's College London)
A new evolutionarily conserved mechanisms of regulating neural stem cell quiescence
16:40 Elisavet Tika (Universite Libre de Bruxelles)
Spatiotemporal regulation of multipotency during prostate development
CLINICS
17:00 Nicola Valeri (Institute of Cancer Research)
Cancer organoids for forward and reverse translation
17:30 break
CHAIR: Juergen KNOBLICH
17:45 Keynote lecture: Lorenz Studer (Memorial Sloan Kettering Institute)
Modeling and treating neural disease using human pluripotent stem cells
18:45 Closing remarks
19:00 Networking: join us on REMO
NETWORKING SESSIONS
Join us in REMO to meet your colleagues, our speakers, exhibitors or some editors!
| Day 1 – Wednesday March 3rd | Day 2 – Thursday March 4th | Day 3 – Friday March 5th |
Floor 1 | Poster: 1 – 10
Meet the Exhibitor: Szabo Scandic, STEMCELL Technologies & GenScript | Poster: 23 - 32
Meet the Exhibitor: Szabo Scandic, STEMCELL Technologies & GenScript | Poster: 44 - 53
Meet the Exhibitor: Szabo Scandic, STEMCELL Technologies & GenScript |
Floor 2 | Poster: 11 - 22
Meet the Exhibitor: Bio-Techne, CELLINK, Development | Poster: 33 - 43
Meet the Exhibitor: Bio-Techne, CELLINK, Development | Poster: 54 - 65
Meet the Exhibitor: Bio-Techne, CELLINK, Development |
Floor 3 | Meet the speaker (1st break): Cantas ALEV & Graziano MARTELLO
Meet the editor(1st break): Nature Methods: Madhura Mukhopadhyay (Associate Scientific Editor)
Meet the speaker (2nd break): Amy WAGERS, Christa BUECKER & Sasha MENDJAN
| Meet the speaker (1st break): Miki EBISUYA, Grayson CAMP, Yekaterina MIROSHNIKOVA & Denise SERRA
Meet the editor (1st break): Development: Seema Grewal (Senior Editor)
Meet the speaker (2nd break): Jens PUSCHHOF, Meritxell HUCH & Kim JENSEN
| Meet the speaker (1st break): Florian MERKLE & Gerald SCHWANK
Meet the VBC Scientific Training Coordinator (1st break): Eva SCHMID
Meet the speaker (2nd break): Nicola VALERI & Lorenz STUDER
|
Floor 4 | Come to this floor in case you are up to meet new people! | Come to this floor in case you are up to meet new people! | Come to this floor in case you are up to meet new people! |
Poster Presenters DAY 1 Wednesday March 3rd
Post No. / table number in REMO | Title | Presenter name |
1 | Hypoxia conditioned mesenchymal stem cell-derived extracellular vesicles induce increased in vitro vascular tube formation | Ciarra Almeria |
2 | Utilising equine adult and embryonic stem cell-derived tenocytes to model the impact of interleukin 1 beta on inflammatory signa | Ross Beaumont |
3 | Plasticity of oesophageal epithelial stem cells: A model of ectopic niche regeneration | Maria Bejar |
4 | Development and Homeostasis in sea anemones and jellyfish: a multi-faceted approach to characterize Cnidarian stem cells | Alison G. Cole |
5 | Modeling CBFA2T3-GLIS2-driven acute megakaryoblastic leukemia using human induced pluripotent stem cell differentiation | Klaus Fortschegger |
6 | Robustness of adult neurogenesis maintains homeostasis and neutralises the early detrimental effects of intermittent fasting | Rut Gabarró Solanas |
7 | A standardized bone organ model of human hematopoiesis | Ani Grigoryan |
8 | How human microglia shape developing neurons in retinal organoids | Verena Huebschmann |
9 | Organoid modelling reveals virus-specific responses leading to microcephaly | Veronica Krenn |
10 | Novel surface markers to isolate human megakaryocyte progenitors | Moyra Lawrence |
11 | Mutational Processes in Intestinal Stem Cells in Response to High Fat Diet | Mathilde Meyenberg |
12 | Non-invasive online monitoring of stem cell aggregate cultivation in a stirred tank bioreactor | Sabrina Nebel |
13 | Understanding the genetic basis of fracture risk in Thoroughbred horses using a stem cell approach | Esther Palomino Lago |
14 | A long-lived population of stem cells under neutral competition shapes the clonal composition of cerebral organoids | Florian Pflug |
15 | Round, reliable cell spheroids for reproducible cell-based assays | Annamarija Raic |
16 | Impaired Differentiation: Understanding a Single Cell State Transition | Merrit Romeike |
17 | Oral stem cells as a potential source for dopaminergic neurons | Theresia Schlothauer |
18 | Investigation of different cell sources and their influence on endothelial cell network quality | Sanja Sladic |
19 | Investigation of m6A modified lncRNAs for glioma prognosis | Rytis Stakaitis |
20 | Modelling Spastic Paraplegia and Psychomotor Retardation with or without Seizures (SPPRS) Using Patient-Derived Stem Cells | Marta Suarez-Cubero |
21 | Interplay of Oncogenic Fusions and Cellular Context in Sarcoma | Stefan Terlecki-Zaniewicz |
22 | Human Bone Marrow Adipose Tissue: Novel Stem Cell Niche Complexity and Perspective | Drenka Trivanovic |
Poster presenters DAY 2 Thursday March 4th
Post No. / table number in REMO | Title | Presenter name |
23 | Distinct and Sequential Functions of PRC2 in Radial Glia Lineage Progression | Nicole Amberg |
24 | Syndecan-4 Modulates Cell Polarity and Migration by Influencing Centrosome Positioning and Intracellular Calcium Distribution | Daniel Becsky |
25 | Induced neurons to evaluate psychiatric risk for Alzheimer’s disease development and progression | Lena Böhnke |
26 | A novel 3D screening approach to define transcriptional regulatory circuitries that regulate endo-mesodermallineage commitment | Kitti Dora Csalyi |
27 | Overlapping Definitive Progenitor Waves Divide and Conquer to Build a Layered Hematopoietic System | Laina Freyer |
28 | Introducing and restoring Craniosynostosis-related gene mutations using prime-editing | Max Gijsbertsen |
29 | Cultrex™ UltiMatrix BME–A Versatile New Matrix for Organoid and Stem Cell Culture | Yas Heidari |
30 | Tilorone improves glucose uptake in myoblasts by increasing BMP signaling and glucose transporter levels | Zoltán Márton Köhler |
31 | Stemness features of mesenchymal stem cells from exfoliated dedicious and permanent teeth: modulatory effects of IL-17 and bFGF | Tamara Kukolj |
32 | p57 is a gatekeeper that limits the injury response of gastric chief cells | Ji-Hyun Lee |
33 | Human pluripotent stem cell-derived neurons as an in vitro model for studying neural stress and CDK5 signaling | Sofía Mucci |
34 | Preclinical safety evaluation of intranasally delivered Mesenchymal Stem Cells for Clinical Application | Laura Olmedo-Moreno |
35 | In vitro differentiated epicardium interacts with self-organizing human cardioids | Nora Papai |
36 | Comparison of fracture healing and limb regeneration in aged axolotls to murine fracture healing. | Anastasia Polikarpova |
37 | RAPID GENERATION OF FUNCTIONAL SENSORY NEURONS FROM HUMAN IPSC BY OVEREXPRESSION OF NGN1, BRN3A and ISLET1 | Pascal Röderer |
38 | Determination of the role of stem cell characteristics as key factors, allowing the production of wished molecules and changing the cellular differentiation direction | Iskra Sainova |
39 | MODELING DRUG-INDUCED CARDIOTOXICITY UTILIZING HPSC-DERIVED CARDIOMYOCYTES: TOWARDS PROTECTIVE THERAPY FOR THE HEART | Verena Schwach |
40 | Developing Novel Methods to Protect Endogenous Tenocytes from Inflammation using Equine Embryonic Stem Cells | Emily Smith |
41 | The Connection Between Deregulated Glioma Stem Cells Genes and GBM Subtype | Giedrius Steponaitis |
42 | Myoblast differentiation, fusion and oncogenesis are influenced by the syndecan-4-mediated activation of Rac1 GTPase | Kitti Szabó |
43 | Genome-engineered human stem cells to study the pathophysiology of ASD related VGCC mutations. | Marcel Tisch |
Poster presenters DAY 3 Friday March 5th
Post No. / table number in REMO | Title | Presenter name |
44 | Defining alternative human naïve pluripotency conditions devoid of MEK/ERK inhibitors | Jonathan Bayerl |
45 | Characterization of human-specific cell cycle regulators in hNSCs using CRISPRi. | Julianne Beirute |
46 | Systematic dissection of an extended naïve pluripotency gene regulatory network | Luis Miguel Cerron Alvan |
47 | Erythropoietin directly remodels the clonal composition of murine hematopoietic multipotent progenitor cells | Almut Eisele |
48 | Neural stem/progenitor cells from the olfactory mucosa in the treatment of spinal cord cysts. | Grigory Fursa |
49 | Exploring a human 3D stem cell-derived model to study astrocyte activation during neuroinflammation | Catarina Gomes |
50 | T-cell specific factor 4 is crucial for Wnt signaling-dependent intestinal stem cell homeostasis and tumorigenesis in mouse | Dusan Hrckulak |
51 | Self-organization of a signaling center in neural tube organoids | Teresa Krammer |
52 | The Fgf/Erf/NCoR axis controls cell fate decisions in Trophoblast Stem Cells | Andreas Lackner |
53 | Deciphering the specification of posterior lateral plate mesoderm | Marie-Christin Leitner |
54 | The Role of MTCH2-mediated Mitochondrial Fusion in Regulating the Quiescence of Hematopoietic Stem Cells | Michael Mullokandov |
55 | Exploring H3K27me3 dynamic at pericentromeric heterochromatin in mouse early embryo | Mélanie Pailles |
56 | 3D self-organized microvascular network on a chip model formed by hiPSC-derived endothelial cells and pericytes | Selin Pars |
57 | IPSC-derived pericytes for the alleviation of the muscle phenotype in myotonic dystrophy type 1 | Renée Raaijmakers |
58 | Identification of miRNAs regulated by E2F transcription factors in human embryonic stem cells | Maria Soledad Rodriguez Varela |
59 | Novel imprinted genes exemplify predominantly H3K27me3-dependent imprinting in mouse blastocysts | Laura Santini |
60 | Activity-dependent Gene Modulation in Glia-derived Induced Neurons | Nesrin Sharif |
61 | Reprogramming and rejuvenation trajectories of the direct conversion of human fibroblasts into induced neural stem cells | Angeliki Spathopoulou |
62 | A self-generated Toddler gradient directs mesodermal cell migration during zebrafish gastrulation | Jessica Stock |
63 | Development of a human in vitro model to study the effects of age on adult neural stem cell quiescence | Katherina Tavernini |
64 | Optimized culture conditions to generate fully-formed 3D human retinal organoids to model inherited blinding diseases | Patrizia Tornabene |
65 | A human tissue screen identifies a regulator of ER secretion as a brain-size determinant | Christopher Esk |