DAY 1 - Wednesday, April 24

10:00    Registration

11:15   Welcome & introduction

11:30   Steven West (University of Exeter)
Sequence-dependent termination of promoter-proximal transcription in human cells

12:00   Srinivasan Rengachari (Max Planck Institute for Multidisciplinary Sciences)    
Mechanism of Polyadenylation independent RNA Polymerase II termination  

12:20   Javier Caceres (University of Edinburgh)
RNA-quality control of gene expression in health and disease

12:50   lunch break

13:50   Marc Buehler (Friedrich Miescher Institute for Biomedical Research)
Genetic Alterations Precede Epigenetic Gene Silencing

14:20    Dominik Handler (IMBA)
Molecular determinants governing primary piRNA biogenesis in Drosophila

14:40    Tugce Aktas (Max Planck Institute for Molecular Genetics)
Genome Streamlining by Nuclear Speckles

15:10    coffee break        

15:40    PhD workshop pt.1        

Anna Uzonyi (Weizmann Institute of Science)
Exclusion of m6A from splice-site-proximal regions by the exon junction complex dictates m6A topologies and mRNA stability

Felix Ostwaldt (Freie Universität Berlin)
From exons to export: How alternative splicing modulates the secretion specificity for large proteins

Jana Brunner (Friedrich Miescher Institute for Biomedical Research)
The RNA-binding protein LIN28 controls developmental timing through only two targets, let-7 miRNA and lin-46 mRNA

Martin Lacroix (INRAE Institut)    
Relationship between RNA silencing and DNA damage/repair  

 Alexander Rotsch (MPI NAT)
Molecular Mechanism of Co-Transcriptional Cap-Snatching


16:55    coffee break        

17:25    Marko Jovanovic (Columbia University)
SPIDR: studying protein-RNA interactions at scale

17:55    Madalena M. Reimão Pinto (Biozentrum Basel)
The regulatory landscape of 5′ UTRs in translational control during zebrafish embryogenesis

18:15    David Bartel (Massachusetts Institute of Technology)
Regulation of mRNA Translation and Decay

18:45    symposium dinner at venue

DAY 2 – Thursday, April 25

09:00        Yiliang Ding (John Innes Centre)    
RNA structure, an important regulator in living cells

09:30        Ulrich Hohmann (IMP & IMBA)    
A molecular switch orchestrates the export of human messenger RNA

09:50         Massimiliano Clamer (Immagina Biotech) [exhibitor talk] 
Unveiling the secrets of translation combining multiple omics 

10:00        Evelina Tutucci (Vrije Universiteit Amsterdam)    
Subcellular mRNA localization in fungi: from single yeast cells to biofilms       

10:30        coffee break        

11:00        PhD workshop pt.2        

Anna Kogan (University of Oxford)
Discovering the molecular basis of long-term transcriptional memory

Chunhong Qiu (ETH Zurich)
Assembly mechanism of Integrator's RNA cleavage module

Martino Morici (University of Hamburg)
Novel arrest peptides induce ribosome stalling by short circuiting the ribosomal peptidyltransferase activity

Sandra Köhler (Heidelberg University Biochemistry Center)
Structure of fungal tRNA ligase with RNA reveals conserved substrate binding principles


12:00        coffee break        

12:30        Irma Querques (Max Perutz Labs)
Mechanistic insights into RNA-guided DNA insertion of type V CRISPR-associated transposons

13:00        Feng Zhang (McGovern Institute)
Exploration of Biological Diversity

13:30        lunch         

14:30        PhD workshop pt.3        

Patrick Barendse (Wageningen University)
Thermus thermophilus Argonaute stimulates homologous recombination

Névé Aupérin (Institut Pasteur)
Inheritance of miRNAs Via Yolk Facilitates Progeny Stress Resilience

Jacqueline Cordes (LMU Munich)
Translation-coupled resolution of RNA-protein crosslinks

Anja Trupej (National Institute of Chemistry)
HCR-Proxy identifies the proteome in close proximity of lowly abundant transcripts

15:30        Poster session I        

17:30        end of poster session

Free evening for attendees

DAY 3 – Friday, April 26

9:00    Marco Hein (Max Perutz Labs)
Single-cell functional genomics of virus/host systems

9:30    Balwina Koopal (Wageningen University)
Function and mechanism of the short prokaryotic Argonaute system SPARTA

9:50    Elizabeth Kellogg (St. Jude Children’s Research Hospital)
New Frontiers in Understanding and Improving RNA-guided DNA integration 

10:20    coffee break    

10:50    Peter Sarkies (University of Oxford)
Evolution of small RNAs: the curious case of the missing piRNAs

11:20    Vasti Thamara Juarez Gonzalez (Swedish University of Agricultural Sciences)    
Unveiling the Role of tRNA Halves in Arabidopsis thaliana Male Gametogenesis

11:40    Danny Nedialkova (Max Planck Institute of Biochemistry) EMBO YIP lecture
The dynamics and functional impact of tRNA repertoires in differentiation and development

12:10    lunch        

13:10    poster session II        

14:40    Alex Borodavka (University of Cambridge) EMBO YIP lecture
How do RNA viruses use RNP granules and RNA chaperones to assemble multi-segmented genomes?

15:10    Akanksha Thawani (UC Berkeley)    
Genetic Architects: How the LINE-1 Transposon Crafts Third of Your Genome

15:30    Alfredo Castello (University of Glasgow)
When viral RNA met the cell: a story of protein-RNA interactions

16:00    PhD award & closing remarks awards        

16:15    Light bites & socializing