DAY 1 - Wednesday, April 24
10:00 Registration
11:15 Welcome & introduction
11:30 Steven West (University of Exeter)
Sequence-dependent termination of promoter-proximal transcription in human cells
12:00 Srinivasan Rengachari (Max Planck Institute for Multidisciplinary Sciences)
Mechanism of Polyadenylation independent RNA Polymerase II termination
12:20 Javier Caceres (University of Edinburgh)
RNA-quality control of gene expression in health and disease
12:50 lunch break
13:50 Marc Buehler (Friedrich Miescher Institute for Biomedical Research)
Genetic Alterations Precede Epigenetic Gene Silencing
14:20 Dominik Handler (IMBA)
Molecular determinants governing primary piRNA biogenesis in Drosophila
14:40 Tugce Aktas (Max Planck Institute for Molecular Genetics)
Genome Streamlining by Nuclear Speckles
15:10 coffee break
15:40 PhD workshop pt.1
Anna Uzonyi (Weizmann Institute of Science)
Exclusion of m6A from splice-site-proximal regions by the exon junction complex dictates m6A topologies and mRNA stability
Felix Ostwaldt (Freie Universität Berlin)
From exons to export: How alternative splicing modulates the secretion specificity for large proteins
Jana Brunner (Friedrich Miescher Institute for Biomedical Research)
The RNA-binding protein LIN28 controls developmental timing through only two targets, let-7 miRNA and lin-46 mRNA
Martin Lacroix (INRAE Institut)
Relationship between RNA silencing and DNA damage/repair
Alexander Rotsch (MPI NAT)
Molecular Mechanism of Co-Transcriptional Cap-Snatching
16:55 coffee break
17:25 Marko Jovanovic (Columbia University)
SPIDR: studying protein-RNA interactions at scale
17:55 Madalena M. Reimão Pinto (Biozentrum Basel)
The regulatory landscape of 5′ UTRs in translational control during zebrafish embryogenesis
18:15 David Bartel (Massachusetts Institute of Technology)
Regulation of mRNA Translation and Decay
18:45 symposium dinner at venue
DAY 2 – Thursday, April 25
09:00 Yiliang Ding (John Innes Centre)
RNA structure, an important regulator in living cells
09:30 Ulrich Hohmann (IMP & IMBA)
A molecular switch orchestrates the export of human messenger RNA
09:50 Massimiliano Clamer (Immagina Biotech) [exhibitor talk]
Unveiling the secrets of translation combining multiple omics
10:00 Evelina Tutucci (Vrije Universiteit Amsterdam)
Subcellular mRNA localization in fungi: from single yeast cells to biofilms
10:30 coffee break
11:00 PhD workshop pt.2
Anna Kogan (University of Oxford)
Discovering the molecular basis of long-term transcriptional memory
Chunhong Qiu (ETH Zurich)
Assembly mechanism of Integrator's RNA cleavage module
Martino Morici (University of Hamburg)
Novel arrest peptides induce ribosome stalling by short circuiting the ribosomal peptidyltransferase activity
Sandra Köhler (Heidelberg University Biochemistry Center)
Structure of fungal tRNA ligase with RNA reveals conserved substrate binding principles
12:00 coffee break
12:30 Irma Querques (Max Perutz Labs)
Mechanistic insights into RNA-guided DNA insertion of type V CRISPR-associated transposons
13:00 Feng Zhang (McGovern Institute)
Exploration of Biological Diversity
13:30 lunch
14:30 PhD workshop pt.3
Patrick Barendse (Wageningen University)
Thermus thermophilus Argonaute stimulates homologous recombination
Névé Aupérin (Institut Pasteur)
Inheritance of miRNAs Via Yolk Facilitates Progeny Stress Resilience
Jacqueline Cordes (LMU Munich)
Translation-coupled resolution of RNA-protein crosslinks
Anja Trupej (National Institute of Chemistry)
HCR-Proxy identifies the proteome in close proximity of lowly abundant transcripts
15:30 Poster session I
17:30 end of poster session
Free evening for attendees
DAY 3 – Friday, April 26
9:00 Marco Hein (Max Perutz Labs)
Single-cell functional genomics of virus/host systems
9:30 Balwina Koopal (Wageningen University)
Function and mechanism of the short prokaryotic Argonaute system SPARTA
9:50 Elizabeth Kellogg (St. Jude Children’s Research Hospital)
New Frontiers in Understanding and Improving RNA-guided DNA integration
10:20 coffee break
10:50 Peter Sarkies (University of Oxford)
Evolution of small RNAs: the curious case of the missing piRNAs
11:20 Vasti Thamara Juarez Gonzalez (Swedish University of Agricultural Sciences)
Unveiling the Role of tRNA Halves in Arabidopsis thaliana Male Gametogenesis
11:40 Danny Nedialkova (Max Planck Institute of Biochemistry) EMBO YIP lecture
The dynamics and functional impact of tRNA repertoires in differentiation and development
12:10 lunch
13:10 poster session II
14:40 Alex Borodavka (University of Cambridge) EMBO YIP lecture
How do RNA viruses use RNP granules and RNA chaperones to assemble multi-segmented genomes?
15:10 Akanksha Thawani (UC Berkeley)
Genetic Architects: How the LINE-1 Transposon Crafts Third of Your Genome
15:30 Alfredo Castello (University of Glasgow)
When viral RNA met the cell: a story of protein-RNA interactions
16:00 PhD award & closing remarks awards
16:15 Light bites & socializing