09:00    Registration

10:00   Welcome & introduction

10:15   Stephen Buratowski (Harvard Medical School)

Single molecule microscopy reveals unexpected features of RNA pol II transcription

10:45   Rippei Hayashi (The John Curtin School of Medical Research)

Revised timing of splicing and chemical modifications during mammalian mRNA synthesis

11:15    Lijuan Pang (WuXi) – sponsor talk

Targeting a KCNA2 Loss-of-Function Variant with Gamper ASOs: Toward Personalized Therapy for Kv1.2 Channelopathies

11:30   coffee break

12:00   Claudia Höbartner (Julius-Maximilians-Universität Würzburg)

Posttranscriptional RNA modification using methyltransferase ribozymes

12:30  Kevin Sabath (IMP)

Recognition of nascent RNA 5’ termini by PPRC1 drives transcription of translation-associated genes

12:50   lunch break

PhD workshop pt.1  

13:50    Wiktor Antczak (International Institute of Molecular and Cell Biology)

Poly(A) tail dynamics regulate ER-associated mRNA stability in a tissue-specific manner

14:10    Ralf Jansen (IMBA)
TFIIA cleavage by Taspase 1 enables transcription in heterochromatin

14:30    coffee break

15:00    Annamaria Hlavata (ISTA)

Structure of cytoplasmic RNA polymerase II

15:20    Minseok Jeong (Seoul National University)

Structural basis for chaperone-guided assembly of RNA-induced silencing complex

15:40    Gaia Loucas (University of Colorado Boulder)

dsRNA-Induced Foci as Nodes for Innate Immune Regulation             

16:00    coffee break

16:30   Marvin Tanenbaum (Hubrecht Institute)

Decoding the sequence requirements for translation initiation

17:00   Madalena Reimão Pinto (Max Planck Institute of Molecular Cell Biology and Genetics)

Decoding the regulatory roles of 5′ UTRs during embryogenesis

17:30   Poster Session 1

19:30   symposium dinner at venue

09:00  Christine Mayr (Memorial Sloan Kettering Cancer Center)

3′UTR-3′UTR interactions drive protein heterodimerization in the Wnt pathway

09:30   Narry Kim (Seoul National University)

Viral and cellular regulation of mRNA stability

10:00   Marko Jovanovic (Columbia University)

Understanding RNA Binding Proteins through their interaction networks

10:30   Annamaria Sgromo (Max Perutz Labs)

Kinetic logic of uridylation-mediated RNA decay

10:50    coffee break    

PhD workshop pt.2   

11:20   Daan Overwijn (University of Basel)

PAIP1 links mRNA export to poly(A) binding protein remodeling and poly(A) homeostasis

11:40   Gerald Raffl (Max Perutz Labs)

Redundant nuclear RNA decay pathways cooperate to degrade excised introns

12:00   Josef Roehsner (IMP) 

Deciphering regulation and functional conservation of dormant ribosomes

12:20   coffee break

12:50   Mateusz Walter (University of Vienna)

Mechanistic insights into DNA processing by Type I CRISPR-associated transposases

13:10   Qiheng Xu (Peking University)

Transcriptional and translational signatures of ovarian aging in Drosophila melanogaster based on transposable elements

13:30   group picture & lunch 

14:30   Aude Bernheim (Institut Pasteur) EMBO Young Investigator Lecture

Evolution of immunity across domains of life

15:00   Sung Chul Kwon (The University of Hong Kong)

Molecular basis of target RNA cleavage by Cas13

15:30   David Bartel (Massachusetts Institute of Technology)

How the cell targets specific microRNAs for degradation

16:00   Poster Session 2

18:00   end of session

19:00   Reception at Wiener Rathauskeller (open to all)

09:30   Igor Ulitsky (Weizmann Institute of Science)

A TRIP through splicing

10:00  Jack Bravo (ISTA)

Self/non-self discrimination by bacterial Argonautes

10:20   Claudia Köhler (Max Planck Institute of Molecular Plant Physiology)

Mobile small RNAs controlling plant reproduction

10:50   coffee break

11:20   Yijun Qi (Tsinghua University)

A transposon-derived small RNA network modulates rice grain quality via epigenetic inheritance

11:50  Kerstin Dörner (University of Basel)

Selective recruitment of stalled mRNPs to nuclear speckles links splicing arrest to RNA quality control

12:10  Daniel Benhalevy (Tel Aviv University)             

Cell cycle-informed studies of hnRNPC reveal Transcriptome Vulnerabilities of rapidly dividing cells

12:30   lunch break

13:30   Claudia Kutter (Karolinska Institutet)

A single strand for surplus: RNA control of lipid fate

14:00   Virginia Busetto (Max Perutz Labs)     

Regulation of RNA cleavage and poly(UG)ylation by CPUG, a CPA-like complex

14:20   Geraldine Seydoux (Johns Hopkins University School of Medicine)

Anticorrelation between translation and RNA condensation as revealed by single-molecule analyses in C. elegans embryos

14:50   coffee break

15:20   Witold Filipowicz (FMI Basel)

Traversing the RNA World: lessons from the past and some ideas for the future

16:20   Awards & closing remarks