Programme

12.00     Registration

13.15     Welcome & introduction

Session 1 - Pluripotency, differentiation & reprogramming

13.30     Joerg Betschinger:  Lysosomal signalling is essential for embryonic stem cell differentiation and human development 

14.00     Yaqub Hanna: Mechanisms for Assembling and Resolving Naïve Pluripotency

14.30     Kikue Tachibana: Single-nucleus Hi-C reveals zygotic genome architecture is organized by cohesin-dependent loop extrusion

14.50      Frank Edenhofer: Exploring novel reprogramming pathways for biomedical applications – Induced neural stem cells ameliorate chronic neuroinflammation    

15.10      Coffee break   

15.45     Gabsang Lee: Establishment of Light-inducible control of Stem Cell Fate 

16.15     Graziano Martello: Transcriptional regulation of naive pluripotency

16.45     Hannah Stuart: Establishment of cellular identity via functionally distinct routes with a unifying transition logic

17.05      Grațiela Dobîrtā: Funding possibilities of the European Research Council

17.45     keynote lecture: Magdalena Zernicka-Goetz: Building the mammalian embryo: in vivo and in vitro

18.45     Dinner

Session 2 -  Adult stem cells & model organisms

09.00     Nadia Mercader Huber: Cardiomyocyte plasticity during heart regeneration in the zebrafish    

09.30     Enzo Porrello: Metabolic and transcriptional control of mammalian heart regeneration    

10.00     Coffee break

10.30     Tom Hiu Tung Cheung: Differential mRNA processing during muscle stem cell activation  

11.00     Charles Chan: Temporal/Spatial Transcriptomic analysis of Normal and Neoplastic Stem Cell Niches

11.30     Elif Eroglu: Cardiac Regeneration in the newt species Pleurodeles waltl

11.50     Coffee break 

Session 3 - Organoids & bioengineering

12.20     Meritxell Huch: Liver organoids for the study of liver biology and disease 

12.50     Agnete Kirkeby: Modelling human rostro-caudal neural patterning with microfluidic gradients

13.20     Lunch

14.30     Anne Grapin-Botton: Pancreas organoids to deconstruct developmental mechanisms

15.00     Giorgia Quadrato: Cell diversity and network dynamics in photosensitive human brain organoids

15.30     Joep Beumer: Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signaling gradient 

15.50     Judith Kraiczy: DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development

First author session

09.00     Jérôme Chal: Developing the next generation of hiPSC-based assay platforms: biomedical relevance and applications for striated muscles

09.20     Patricia Garcez: Cerebral Organoids and Neurospheres as Models to Study Microcephaly associated with Zika virus in vitro

09.40     Malkiel Cohen: Stem cell derived neural crest chimeras for modeling human diseases in vivo

10.00     Prayag Murawala: Single-cell transcriptomics uncovers molecular funneling of cell identities during axolotl limb regeneration

10.20     Coffee break 

10.50     Marisa Karow: Probing the transcriptional programs underlying human neurogenesis by direct lineage reprogramming

11.10     Sven Falk: Molecular control of lineage diversification in the ventral telencephalon    

11.30     Break

Session 4 - Technologies & emerging methods

11.40     Barbara Treutlein: Reconstructing human organ development using single-cell transcriptomics    

12.10     Fatma Uzbas: Massive Single Cell Targeted Transcriptomics Reveals Subpopulations of Human Pluripotent Stem Cells

12.30     Lunch & Poster Session

Session 5 - Clinical outlooks

14.30     Barbara Ludwig: Current status and future perspectives in diabetes therapy- from cells, pills, and chimera

15.00     Markus Manz: Inflamm-Ageing of Hematopoietic Stem Cells

15.30    Fotis Sampaziotis: Cholangiocyte organoids for clinical applications

16.00    Coffee Break

16.30     Keynote lecture: Marius Wernig: How to Make a Neuron