List of Publications

YearTitleJournalAuthors
2025Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression.PLoS BiolChavan, A., Skrutl, L., Uliana, F (...) Brennecke, J., Jagannathan, M.
2024Selfish conflict underlies RNA-mediated parent-of-origin effects.NaturePliota, P., Marvanova, H., Koreshova, A (...) Ben-David, E., Burga, A.
2024 A molecular switch orchestrates the nuclear export of human messenger RNA BioRxivHohmann, U., Graf, M., Schellhaas, U (...) Brennecke, J., Plaschka, C.
2024Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals.ElifeBaumgartner, L., Ipsaro, JJ., Hohmann, U (...) Duchek, P., Brennecke, J.
2024Proteome-scale tagging and functional screening in mammalian cells by ORFtag.Nat MethodsNemčko, F., Himmelsbach, M., Loubiere, V (...) Stark, A., Ameres, SL.
2024A lyophilized open-source RT-LAMP assay for molecular diagnostics in resource-limited settingsmedRxivMatl. M.*, Kellner, M.J. *, Ansah, F. *, Grishkovskaya, I., Handler, D., Heinen, R (...) Penninger, J.M., Vienna Covid-19 Detection Initiative (VCDI), Awandare, G.A.#, Brennecke, J.#, Pauli, A.#.
2023 Functional Adaptations of Endogenous Retroviruses to the Drosophila Host Underlie their Evolutionary Diversification BioRxivSenti, KA., Handler, D., Rafanel, B (...) Schloetterer, C., Brennecke, J.
2023 Evolutionary adaptation of the chromodomain of the HP1-protein Rhino allows the integration of chromatin and DNA sequence signals BioRxivL Baumgartner, JJ Ipsaro, U Hohmann, D Handler, A Schleiffer, P Duchek, J Brennecke
2023ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers.Nat Cell BiolYelagandula, R., Stecher, K., Novatchkova, M (...) Brennecke, J., Bell, O.
2022Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery.Nat Struct Mol BiolAndreev, VI., Yu, C., Wang, J (...) Patel, DJ., Brennecke, J.
2022The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters.ElifeBaumgartner, L., Handler, D., Platzer, SW (...) Duchek, P., Brennecke, J.
2022A Rapid, Highly Sensitive and Open-Access SARS-CoV-2 Detection Assay for Laboratory and Home Testing.Front Mol BiosciKellner, MJ., Ross, JJ., Schnabl, J (...) Pauli, A., Brennecke, J.
2021Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RT-qPCR on extracted RNA for rapid SARS-CoV-2 diagnostics.medRxivKellner MJ, Matl M, Ross JJ, Schnabl J, Handler D, Heinen R, Schaeffer J, Hufnagl P, Indra A, Dekens MPS, Fritsche-Polanz R, Födinger M, Zuber J, Vienna Covid-19 Detection Initiative (VCDI), Allerberger F, Pauli A, Brennecke J
2021Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.Genes DevSchnabl, J., Wang, J., Hohmann, U (...) Patel, DJ., Brennecke, J.
2021A genetic toolkit for studying transposon control in the Drosophila melanogaster ovary.GeneticsElMaghraby, MF., Tirian, L., Senti, KA., Meixner, K., Brennecke, J.
2020Structure-function analysis of microRNA 3'-end trimming by Nibbler.Proc Natl Acad Sci U S AXie, W., Sowemimo, I., Hayashi, R (...) Ameres, SL., Patel, DJ.
2020Structure of the human core transcription-export complex reveals a hub for multivalent interactions.ElifePühringer, T., Hohmann, U., Fin, L (...) Brennecke, J., Plaschka, C.
2020A universal method for the rapid isolation of all known classes of functional silencing small RNAs.Nucleic Acids ResGrentzinger, T., Oberlin, S., Schott, G (...) Brennecke, J., Voinnet, O.
2019A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production.CellElMaghraby, MF., Andersen, PR., Pühringer, F (...) Tirian, L., Brennecke, J.
2019The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.Nat Struct Mol BiolBatki, J., Schnabl, J., Wang, J (...) Patel, DJ., Brennecke, J.