List of Publications

YearTitleJournalAuthors
2021Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.Genes DevSchnabl, J., Wang, J., Hohmann, U., Gehre, M., Batki, J., Andreev, VI., Purkhauser, K., Fasching, N., Duchek, P., Novatchkova, M., Mechtler, K., Plaschka, C., Patel, DJ., Brennecke, J.
2021Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RT-qPCR on extracted RNA for rapid SARS-CoV-2 diagnostics.medRxivKellner MJ, Matl M, Ross JJ, Schnabl J, Handler D, Heinen R, Schaeffer J, Hufnagl P, Indra A, Dekens MPS, Fritsche-Polanz R, Födinger M, Zuber J, Vienna Covid-19 Detection Initiative (VCDI), Allerberger F, Pauli A, Brennecke J
2020Structure of the human core transcription-export complex reveals a hub for multivalent interactions.ElifePühringer, T., Hohmann, U., Fin, L., Pacheco-Fiallos, B., Schellhaas, U., Brennecke, J., Plaschka, C.
2020A universal method for the rapid isolation of all known classes of functional silencing small RNAs.Nucleic Acids ResGrentzinger, T., Oberlin, S., Schott, G., Handler, D., Svozil, J., Barragan-Borrero, V., Humbert, A., Duharcourt, S., Brennecke, J., Voinnet, O.
2020A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testingbioRxivKellner MJ, Ross JJ, Schnabl J, Dekens MPS, Heinen R, Grishkovskaya I, Bauer B, Stadlmann J, Menéndez-Arias L, Fritsche-Polanz R, Traugott M, Seitz T, Zoufaly A, Födinger M, Wenisch C, Zuber J, Vienna Covid-19 Detection Initiative (VCDI), Pauli A, Brennecke J
2020Structure-function analysis of microRNA 3'-end trimming by Nibbler.Proc Natl Acad Sci U S AXie, W., Sowemimo, I., Hayashi, R., Wang, J., Burkard, TR., Brennecke, J., Ameres, SL., Patel, DJ.
2019The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.Nat Struct Mol BiolBatki, J., Schnabl, J., Wang, J., Handler, D., Andreev, VI., Stieger, CE., Novatchkova, M., Lampersberger, L., Kauneckaite, K., Xie, W., Mechtler, K., Patel, DJ., Brennecke, J.
2019A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production.CellElMaghraby, MF., Andersen, PR., Pühringer, F., Hohmann, U., Meixner, K., Lendl, T., Tirian, L., Brennecke, J.
2017A heterochromatin-dependent transcription machinery drives piRNA expression.NatureAndersen, PR., Tirian, L., Vunjak, M., Brennecke, J.
2016Genetic and mechanistic diversity of piRNA 3'-end formation.NatureHayashi, R., Schnabl, J., Handler, D., Mohn, F., Ameres, SL., Brennecke, J.
2015Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi's genomic targets still not identified.Dev CellMarinov, GK., Wang, J., Handler, D., Wold, BJ., Weng, Z., Hannon, GJ., Aravin, AA., Zamore, PD., Brennecke, J., Toth, KF.
2015piRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire.Genes DevSenti, KA., Jurczak, D., Sachidanandam, R., Brennecke, J.
2015Noncoding RNA. piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis.ScienceMohn, F., Handler, D., Brennecke, J.
2015Silencio/CG9754 connects the Piwi-piRNA complex to the cellular heterochromatin machinery.Genes DevSienski, G., Batki, J., Senti, KA., Dönertas, D., Tirian, L., Meixner, K., Brennecke, J.
2014The exon junction complex is required for definition and excision of neighboring introns in Drosophila.Genes DevHayashi, R., Handler, D., Ish-Horowicz, D., Brennecke, J.
2014The rhino-deadlock-cutoff complex licenses noncanonical transcription of dual-strand piRNA clusters in Drosophila.CellMohn, F., Sienski, G., Handler, D., Brennecke, J.
2013Drosophila Gtsf1 is an essential component of the Piwi-mediated transcriptional silencing complex.Genes DevDönertas, D., Sienski, G., Brennecke, J.
2013The genetic makeup of the Drosophila piRNA pathway.Mol CellHandler, D., Meixner, K., Pizka, M., Lauss, K., Schmied, C., Gruber, FS., Brennecke, J.
2012Preparation of small RNA libraries for high-throughput sequencing.Cold Spring Harb ProtocMalone, C., Brennecke, J., Czech, B., Aravin, A., Hannon, GJ.
2012Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression.CellSienski, G., Dönertas, D., Brennecke, J.