2023 | ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers. | Nat Cell Biol | Yelagandula, R., Stecher, K., Novatchkova, M., Michetti, L., Michlits, G., Wang, J., Hofbauer, P., Vainorius, G., Pribitzer, C., Isbel, L., Mendjan, S., Schübeler, D., Elling, U., Brennecke, J., Bell, O. |
2022 | The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters. | Elife | Baumgartner, L., Handler, D., Platzer, SW., Yu, C., Duchek, P., Brennecke, J. |
2022 | Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery. | Nat Struct Mol Biol | Andreev, VI., Yu, C., Wang, J., Schnabl, J., Tirian, L., Gehre, M., Handler, D., Duchek, P., Novatchkova, M., Baumgartner, L., Meixner, K., Sienski, G., Patel, DJ., Brennecke, J. |
2022 | A Rapid, Highly Sensitive and Open-Access SARS-CoV-2 Detection Assay for Laboratory and Home Testing. | Front Mol Biosci | Kellner, MJ., Ross, JJ., Schnabl, J., Dekens, MPS., Matl, M., Heinen, R., Grishkovskaya, I., Bauer, B., Stadlmann, J., Menéndez-Arias, L., Straw, AD., Fritsche-Polanz, R., Traugott, M., Seitz, T., Zoufaly, A., Födinger, M., Wenisch, C., Zuber, J., Pauli, A., Brennecke, J. |
2021 | A genetic toolkit for studying transposon control in the Drosophila melanogaster ovary. | Genetics | ElMaghraby, MF., Tirian, L., Senti, KA., Meixner, K., Brennecke, J. |
2021 | Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RT-qPCR on extracted RNA for rapid SARS-CoV-2 diagnostics. | medRxiv | Kellner MJ, Matl M, Ross JJ, Schnabl J, Handler D, Heinen R, Schaeffer J, Hufnagl P, Indra A, Dekens MPS, Fritsche-Polanz R, Födinger M, Zuber J, Vienna Covid-19 Detection Initiative (VCDI), Allerberger F, Pauli A, Brennecke J |
2021 | Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex. | Genes Dev | Schnabl, J., Wang, J., Hohmann, U., Gehre, M., Batki, J., Andreev, VI., Purkhauser, K., Fasching, N., Duchek, P., Novatchkova, M., Mechtler, K., Plaschka, C., Patel, DJ., Brennecke, J. |
2020 | A universal method for the rapid isolation of all known classes of functional silencing small RNAs. | Nucleic Acids Res | Grentzinger, T., Oberlin, S., Schott, G., Handler, D., Svozil, J., Barragan-Borrero, V., Humbert, A., Duharcourt, S., Brennecke, J., Voinnet, O. |
2020 | Structure-function analysis of microRNA 3'-end trimming by Nibbler. | Proc Natl Acad Sci U S A | Xie, W., Sowemimo, I., Hayashi, R., Wang, J., Burkard, TR., Brennecke, J., Ameres, SL., Patel, DJ. |
2020 | Structure of the human core transcription-export complex reveals a hub for multivalent interactions. | Elife | Pühringer, T., Hohmann, U., Fin, L., Pacheco-Fiallos, B., Schellhaas, U., Brennecke, J., Plaschka, C. |
2019 | The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation. | Nat Struct Mol Biol | Batki, J., Schnabl, J., Wang, J., Handler, D., Andreev, VI., Stieger, CE., Novatchkova, M., Lampersberger, L., Kauneckaite, K., Xie, W., Mechtler, K., Patel, DJ., Brennecke, J. |
2019 | A Heterochromatin-Specific RNA Export Pathway Facilitates piRNA Production. | Cell | ElMaghraby, MF., Andersen, PR., Pühringer, F., Hohmann, U., Meixner, K., Lendl, T., Tirian, L., Brennecke, J. |
2017 | A heterochromatin-dependent transcription machinery drives piRNA expression. | Nature | Andersen, PR., Tirian, L., Vunjak, M., Brennecke, J. |
2016 | Genetic and mechanistic diversity of piRNA 3'-end formation. | Nature | Hayashi, R., Schnabl, J., Handler, D., Mohn, F., Ameres, SL., Brennecke, J. |
2015 | Noncoding RNA. piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis. | Science | Mohn, F., Handler, D., Brennecke, J. |
2015 | Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi's genomic targets still not identified. | Dev Cell | Marinov, GK., Wang, J., Handler, D., Wold, BJ., Weng, Z., Hannon, GJ., Aravin, AA., Zamore, PD., Brennecke, J., Toth, KF. |
2015 | Silencio/CG9754 connects the Piwi-piRNA complex to the cellular heterochromatin machinery. | Genes Dev | Sienski, G., Batki, J., Senti, KA., Dönertas, D., Tirian, L., Meixner, K., Brennecke, J. |
2015 | piRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire. | Genes Dev | Senti, KA., Jurczak, D., Sachidanandam, R., Brennecke, J. |
2014 | The rhino-deadlock-cutoff complex licenses noncanonical transcription of dual-strand piRNA clusters in Drosophila. | Cell | Mohn, F., Sienski, G., Handler, D., Brennecke, J. |
2014 | The exon junction complex is required for definition and excision of neighboring introns in Drosophila. | Genes Dev | Hayashi, R., Handler, D., Ish-Horowicz, D., Brennecke, J. |