List of Publications

Gassler, J., Kobayashi, W., Gáspár, I (...) Ladstätter, S., Tachibana, K. (2022). Zygotic genome activation by the totipotency pioneer factor Nr5a2. Science. :eabn7478

Kaiser, FMP., Gruenbacher, S., Oyaga, MR (...) Badura, A., Busslinger, M. (2022). Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder. J Exp Med. 219(9)

Nagano, M., Hu, B., Yokobayashi, S (...) Majewski, J., Saitou, M. (2022). Nucleome programming is required for the foundation of totipotency in mammalian germline development. EMBO J. :e110600

Dequeker, BJH., Scherr, MJ., Brandão, HB (...) Mirny, LA., Tachibana, K. (2022). MCM complexes are barriers that restrict cohesin-mediated loop extrusion. Nature.

Chatzidaki, EE., Powell, S., Dequeker, BJH (...) Silva, MCC., Tachibana, K. (2021). Ovulation suppression protects against chromosomal abnormalities in mouse eggs at advanced maternal age. Curr Biol.

Kobayashi, W., Tachibana, K. (2021). Awakening of the zygotic genome by pioneer transcription factors. Curr Opin Struct Biol. 71:94-100

Silva, MCC., Powell, S., Ladstätter, S (...) Peters, JM., Tachibana, K. (2020). Wapl releases Scc1-cohesin and regulates chromosome structure and segregation in mouse oocytes. J Cell Biol. 219(4)

Vallot, A., Tachibana, K. (2020). The emergence of genome architecture and zygotic genome activation. Curr Opin Cell Biol. 64:50-57

Du, Z., Zheng, H., Kawamura, YK (...) Peters, AHFM., Xie, W. (2020). Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos. Mol Cell. 77(4):825-839.e7

Ladstätter, S., Tachibana, K. (2019). Genomic insights into chromatin reprogramming to totipotency in embryos. J Cell Biol. 218(1):70-82

Silva, MCC., Wutz, G., Tachibana, K., Peters, JM. (2018). Analysis of chromosomes from mouse oocytes and mammalian cultured cells by light microscopy. Methods Cell Biol. 144:287-305

Gassler, J., Flyamer, IM., Tachibana, K. (2018). Single-nucleus Hi-C of mammalian oocytes and zygotes. Methods Cell Biol. 144:389-407

Cuartero, S., Weiss, FD., Dharmalingam, G (...) Fisher, AG., Merkenschlager, M. (2018). Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation. Nat Immunol. 19(9):932-941

Tachibana, K. (2018). The beginning of totipotency. Nat Rev Mol Cell Biol. 19(7):417

Szydłowska, A., Ladstätter, S., Tachibana, K. (2018). Manipulating Cohesin Levels in Live Mouse Oocytes. Methods Mol Biol. 1818:113-128

Ulianov, SV., Tachibana-Konwalski, K., Razin, SV. (2017). Single-cell Hi-C bridges microscopy and genome-wide sequencing approaches to study 3D chromatin organization. Bioessays. 39(10)

Gassler, J., Brandão, HB., Imakaev, M (...) Mirny, LA., Tachibana, K. (2017). A mechanism of cohesin-dependent loop extrusion organizes zygotic genome architecture. EMBO J. 36(24):3600-3618

Flyamer, IM., Gassler, J., Imakaev, M (...) Mirny, LA., Tachibana-Konwalski, K. (2017). Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition. Nature. 544(7648):110-114

Ladstätter, S., Tachibana-Konwalski, K. (2016). A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming. Cell. 167(7):1774-1787.e13

Burkhardt, S., Borsos, M., Szydlowska, A (...) Saitou, M., Tachibana-Konwalski, K. (2016). Chromosome Cohesion Established by Rec8-Cohesin in Fetal Oocytes Is Maintained without Detectable Turnover in Oocytes Arrested for Months in Mice. Curr Biol. 26(5):678-85

Zou, L. (2016). A Zygotic Checkpoint for Unrepaired Lesions. Cell. 167(7):1676-1678

Prakash, K., Fournier, D., Redl, S (...) Cremer, C., Birk, UJ. (2015). Superresolution imaging reveals structurally distinct periodic patterns of chromatin along pachytene chromosomes. Proc Natl Acad Sci U S A. 112(47):14635-40

Tachibana-Konwalski, K. (2015). Cell division: Hold on and let go. Nature. 517(7535):441-2

Rattani, A., Vinod, PK., Godwin, J (...) Novák, B., Nasmyth, K. (2014). Dependency of the spindle assembly checkpoint on Cdk1 renders the anaphase transition irreversible. Curr Biol. 24(6):630-7

Tachibana-Konwalski, K., Godwin, J., Borsos, M (...) Adams, DJ., Nasmyth, K. (2013). Spindle assembly checkpoint of oocytes depends on a kinetochore structure determined by cohesin in meiosis I. Curr Biol. 23(24):2534-9

Yang, VS., Carter, SA., Ng, Y (...) Laskey, RA., Gonzalez, MA. (2012). Distinct activities of the anaphase-promoting complex/cyclosome (APC/C) in mouse embryonic cells. Cell Cycle. 11(5):846-55

Tachibana-Konwalski, K. (2012). Pat(ting) boosts meiosis. Cell Cycle. 11(10):1876-7

Seitan, VC., Hao, B., Tachibana-Konwalski, K (...) Nasmyth, K., Merkenschlager, M. (2011). A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation. Nature. 476(7361):467-71

Yang, VS., Carter, SA., Hyland, SJ (...) Laskey, RA., Gonzalez, MA. (2011). Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog. Curr Biol. 21(8):692-9

Tachibana-Konwalski, K., Godwin, J., van der Weyden, L (...) Adams, DJ., Nasmyth, K. (2010). Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes. Genes Dev. 24(22):2505-16

Tachibana, KE., Nigg, EA. (2006). Geminin regulates multiple steps of the chromosome inheritance cycle. Cell Cycle. 5(2):151-4

Gonzalez, MA., Tachibana, KE., Adams, DJ (...) Bradley, A., Laskey, RA. (2006). Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. Genes Dev. 20(14):1880-4

Gonzalez, MA., Tachibana, KE., Laskey, RA., Coleman, N. (2005). Control of DNA replication and its potential clinical exploitation. Nat Rev Cancer. 5(2):135-41

Tachibana, KE., Gonzalez, MA., Coleman, N. (2005). Cell-cycle-dependent regulation of DNA replication and its relevance to cancer pathology. J Pathol. 205(2):123-9

van der Weyden, L., Tachibana, KK., Gonzalez, MA (...) Arends, MJ., Bradley, A. (2005). The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis. Mol Cell Biol. 25(18):8356-67

Tachibana, KE., Gonzalez, MA., Guarguaglini, G., Nigg, EA., Laskey, RA. (2005). Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects. EMBO Rep. 6(11):1052-7

Gonzalez, MA., Tachibana, KE., Chin, SF (...) Laskey, RA., Coleman, N. (2004). Geminin predicts adverse clinical outcome in breast cancer by reflecting cell-cycle progression. J Pathol. 204(2):121-30