List of Publications

Vrij, E., Rouwkema, J., LaPointe, V (...) Truckenmüller, R., Rivron, N. (2016). Directed Assembly and Development of Material-Free Tissues with Complex Architectures. Adv Mater. 28(21):4032-9

Leferink, A., Schipper, D., Arts, E (...) Moroni, L., Truckenmüller, R. (2014). Engineered micro-objects as scaffolding elements in cellular building blocks for bottom-up tissue engineering approaches. Adv Mater. 26(16):2592-9

Truckenmüller, R., Giselbrecht, S., Rivron, N (...) Wessling, M., van Blitterswijk, C. (2011). Thermoforming of film-based biomedical microdevices. Adv Mater. 23(11):1311-29

Rivron, NC., Rouwkema, J., Truckenmüller, R (...) De Boer, J., Van Blitterswijk, CA. (2009). Tissue assembly and organization: developmental mechanisms in microfabricated tissues. Biomaterials. 30(28):4851-8

Truckenmüller, R., Giselbrecht, S., Escalante-Marun, M (...) de Boer, J., Stamatialis, D. (2012). Fabrication of cell container arrays with overlaid surface topographies. Biomed Microdevices. 14(1):95-107

Rivron, NC., Martinez Arias, A., Pera, MF., Moris, N., M'hamdi, HI. (2023). An ethical framework for human embryology with embryo models. Cell. 186(17):3548-3557

Castel, G., Meistermann, D., Bretin, B (...) Fréour, T., David, L. (2020). Induction of Human Trophoblast Stem Cells from Somatic Cells and Pluripotent Stem Cells. Cell Rep. 33(8):108419

Wangsanuwat, C., Chialastri, A., Aldeguer, JF., Rivron, NC., Dey, SS. (2021). A probabilistic framework for cellular lineage reconstruction using integrated single-cell 5-hydroxymethylcytosine and genomic DNA sequencing. Cell Rep Methods. 1(4)

Seong, J., Frias-Aldeguer, J., Holzmann, V (...) Geijsen, N., Rivron, NC. (2022). Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero. Cell Stem Cell. 29(7):1102-1118.e8

Pham, TXA., Panda, A., Kagawa, H (...) Balaton, BP., Pasque, V. (2022). Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells. Cell Stem Cell. 29(9):1346-1365.e10

David, L., Bruneau, A., Fréour, T., Rivron, N., Van de Velde, H. (2023). An update on human pre- and peri-implantation development: a blueprint for blastoids. Curr Opin Genet Dev. 83:102125

Martin, I., Malda, J., Rivron, NC. (2019). Organs by design: can bioprinting meet self-organization? Curr Opin Organ Transplant. 24(5):562-567

Hiiragi, T., Gladfelter, AS., Miguel-Aliaga, I (...) Ebisuya, M., Lancaster, MA. (2021). 20 years of Developmental Cell: Looking forward. Dev Cell. 56(23):3185-3191

Kicheva, A., Rivron, NC. (2017). Creating to understand - developmental biology meets engineering in Paris. Development. 144(5):733-736

Vrij, EJ., Scholte Op Reimer, YS., Fuentes, LR (...) van Blitterswijk, CA., Rivron, NC. (2022). A pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression. Development. 149(20)

Scialdone, A., Rivron, N. (2022). In preprints: improving and interrogating embryo models. Development. 149(23)

Rivron, NC., Liu J, J., Rouwkema, J., de Boer, J., van Blitterswijk, CA. (2008). Engineering vascularised tissues in vitro. Eur Cell Mater. 15:27-40

Zhao, C., Biondic, S., Vandal, K (...) Reik, W., Petropoulos, S. (2022). Single-cell multi-omics of human preimplantation embryos demonstrates susceptibility to glucocorticoids. Genome Res.

Roovers, S., Deprez, J., Priwitaningrum, D (...) De Smedt, SC., Lentacker, I. (2019). Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound. J Control Release. 316:79-92

Ismaili M'hamdi, H., Rivron, NC., Asscher, EC. (2022). Going high and low: on pluralism and neutrality in human embryology policy-making. J Med Ethics.

Potier, E., Rivron, NC., Van Blitterswijk, CA., Ito, K. (2016). Micro-aggregates do not influence bone marrow stromal cell chondrogenesis. J Tissue Eng Regen Med. 10(12):1021-1032

Kagawa, H., Javali, A., Heidari Khoei, H (...) Scholte Op Reimer, Y., Rivron, N. (2022). Protocol for Human Blastoids Modeling Blastocyst Development and Implantation. J Vis Exp. (186)

Vrij, EJ., Espinoza, S., Heilig, M (...) Truckenmüller, RK., Rivron, NC. (2016). 3D high throughput screening and profiling of embryoid bodies in thermoformed microwell plates. Lab Chip. 16(4):734-42

Zijlmans, DW., Talon, I., Verhelst, S (...) Rugg-Gunn, PJ., Pasque, V. (2022). Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction. Nat Cell Biol. 24(6):858-871

Rivron, NC., Martinez-Arias, A., Sermon, K (...) Rossant, J., Kato, K. (2023). Changing the public perception of human embryology. Nat Cell Biol.

Neagu, A., van Genderen, E., Escudero, I (...) Marks, H., Ten Berge, D. (2020). In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states. Nat Cell Biol. 22(5):534-545

Brivanlou, AH., Rivron, N., Gleicher, N. (2021). How will our understanding of human development evolve over the next 10 years. Nat Commun. 12(1):4614

Heidari Khoei, H., Javali, A., Kagawa, H (...) Scholte Op Reimer, Y., Rivron, N. (2023). Generating human blastoids modeling blastocyst-stage embryos and implantation. Nat Protoc.

Rivron, NC., Frias-Aldeguer, J., Vrij, EJ (...) van Blitterswijk, CA., Geijsen, N. (2018). Blastocyst-like structures generated solely from stem cells. Nature. 557(7703):106-111

Rivron, N., Pera, M., Rossant, J (...) Munsie, M., Isasi, R. (2018). Debate ethics of embryo models from stem cells. Nature. 564(7735):183-185

Kagawa, H., Javali, A., Khoei, HH (...) David, L., Rivron, N. (2021). Human blastoids model blastocyst development and implantation. Nature.

Okubo, T., Rivron, N., Kabata, M (...) Yamamoto, T., Takashima, Y. (2024). Hypoblast from human pluripotent stem cells regulates epiblast development. Nature. 626(7998):357-366

Basak, O., Krieger, TG., Muraro, MJ (...) Simons, BD., Clevers, H. (2018). Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy. Proc Natl Acad Sci U S A. 115(4):E610-E619

Rivron, NC., Vrij, EJ., Rouwkema, J (...) Truckenmüller, RK., van Blitterswijk, CA. (2012). Tissue deformation spatially modulates VEGF signaling and angiogenesis. Proc Natl Acad Sci U S A. 109(18):6886-91

Rivron, NC., Raiss, CC., Liu, J (...) Rouwkema, J., van Blitterswijk, CA. (2012). Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation. Proc Natl Acad Sci U S A. 109(12):4413-8

Seong, J., Rivron, NC. (2023). Protocol for capturing trophectoderm stem cells reflecting the blastocyst stage. STAR Protoc. 4(2):102151

Rivron, N., Fu, J. (2021). It takes a village to form embryo models. Stem Cell Reports. 16(5):1011-1013

Rivron, N., Fu, J. (2021). SnapShot: Embryo models. Stem Cell Reports. 16(5):1142-1142.e1

Lovell-Badge, R., Anthony, E., Barker, RA (...) Zettler, PJ., Zhai, X. (2021). ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem Cell Reports. 16(6):1398-1408

Hyun, I., Munsie, M., Pera, MF., Rivron, NC., Rossant, J. (2020). Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells. Stem Cell Reports. 14(2):169-174

Clark, AT., Brivanlou, A., Fu, J (...) Tang, F., Rossant, J. (2021). Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines. Stem Cell Reports. 16(6):1416-1424

Fennema, E., Rivron, N., Rouwkema, J., van Blitterswijk, C., de Boer, J. (2013). Spheroid culture as a tool for creating 3D complex tissues. Trends Biotechnol. 31(2):108-15

Rouwkema, J., Rivron, NC., van Blitterswijk, CA. (2008). Vascularization in tissue engineering. Trends Biotechnol. 26(8):434-41