List of Publications

Okubo, T., Rivron, N., Kabata, M (...) Yamamoto, T., Takashima, Y. (2024). Hypoblast from human pluripotent stem cells regulates epiblast development. Nature. 626(7998):357-366

David, L., Bruneau, A., Fréour, T., Rivron, N., Van de Velde, H. (2023). An update on human pre- and peri-implantation development: a blueprint for blastoids. Curr Opin Genet Dev. 83:102125

Rivron, NC., Martinez-Arias, A., Sermon, K (...) Rossant, J., Kato, K. (2023). Changing the public perception of human embryology. Nat Cell Biol.

Heidari Khoei, H., Javali, A., Kagawa, H (...) Scholte Op Reimer, Y., Rivron, N. (2023). Generating human blastoids modeling blastocyst-stage embryos and implantation. Nat Protoc.

Rivron, NC., Martinez Arias, A., Pera, MF., Moris, N., M'hamdi, HI. (2023). An ethical framework for human embryology with embryo models. Cell. 186(17):3548-3557

Seong, J., Rivron, NC. (2023). Protocol for capturing trophectoderm stem cells reflecting the blastocyst stage. STAR Protoc. 4(2):102151

Seong, J., Frias-Aldeguer, J., Holzmann, V (...) Geijsen, N., Rivron, NC. (2022). Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero. Cell Stem Cell. 29(7):1102-1118.e8

Ismaili M'hamdi, H., Rivron, NC., Asscher, EC. (2022). Going high and low: on pluralism and neutrality in human embryology policy-making. J Med Ethics.

Zijlmans, DW., Talon, I., Verhelst, S (...) Rugg-Gunn, PJ., Pasque, V. (2022). Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction. Nat Cell Biol. 24(6):858-871

Zhao, C., Biondic, S., Vandal, K (...) Reik, W., Petropoulos, S. (2022). Single-cell multi-omics of human preimplantation embryos demonstrates susceptibility to glucocorticoids. Genome Res.

Vrij, EJ., Scholte Op Reimer, YS., Fuentes, LR (...) van Blitterswijk, CA., Rivron, NC. (2022). A pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression. Development. 149(20)

Kagawa, H., Javali, A., Heidari Khoei, H (...) Scholte Op Reimer, Y., Rivron, N. (2022). Protocol for Human Blastoids Modeling Blastocyst Development and Implantation. J Vis Exp. (186)

Pham, TXA., Panda, A., Kagawa, H (...) Balaton, BP., Pasque, V. (2022). Modeling human extraembryonic mesoderm cells using naive pluripotent stem cells. Cell Stem Cell. 29(9):1346-1365.e10

Scialdone, A., Rivron, N. (2022). In preprints: improving and interrogating embryo models. Development. 149(23)

Brivanlou, AH., Rivron, N., Gleicher, N. (2021). How will our understanding of human development evolve over the next 10 years. Nat Commun. 12(1):4614

Rivron, N., Fu, J. (2021). It takes a village to form embryo models. Stem Cell Reports. 16(5):1011-1013

Rivron, N., Fu, J. (2021). SnapShot: Embryo models. Stem Cell Reports. 16(5):1142-1142.e1

Lovell-Badge, R., Anthony, E., Barker, RA (...) Zettler, PJ., Zhai, X. (2021). ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem Cell Reports. 16(6):1398-1408

Wangsanuwat, C., Chialastri, A., Aldeguer, JF., Rivron, NC., Dey, SS. (2021). A probabilistic framework for cellular lineage reconstruction using integrated single-cell 5-hydroxymethylcytosine and genomic DNA sequencing. Cell Rep Methods. 1(4)

Kagawa, H., Javali, A., Khoei, HH (...) David, L., Rivron, N. (2021). Human blastoids model blastocyst development and implantation. Nature.

Hiiragi, T., Gladfelter, AS., Miguel-Aliaga, I (...) Ebisuya, M., Lancaster, MA. (2021). 20 years of Developmental Cell: Looking forward. Dev Cell. 56(23):3185-3191

Clark, AT., Brivanlou, A., Fu, J (...) Tang, F., Rossant, J. (2021). Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines. Stem Cell Reports. 16(6):1416-1424

Castel, G., Meistermann, D., Bretin, B (...) Fréour, T., David, L. (2020). Induction of Human Trophoblast Stem Cells from Somatic Cells and Pluripotent Stem Cells. Cell Rep. 33(8):108419

Neagu, A., van Genderen, E., Escudero, I (...) Marks, H., Ten Berge, D. (2020). In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states. Nat Cell Biol. 22(5):534-545

Hyun, I., Munsie, M., Pera, MF., Rivron, NC., Rossant, J. (2020). Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells. Stem Cell Reports. 14(2):169-174

Martin, I., Malda, J., Rivron, NC. (2019). Organs by design: can bioprinting meet self-organization? Curr Opin Organ Transplant. 24(5):562-567

Roovers, S., Deprez, J., Priwitaningrum, D (...) De Smedt, SC., Lentacker, I. (2019). Sonoprinting liposomes on tumor spheroids by microbubbles and ultrasound. J Control Release. 316:79-92

Rivron, NC., Frias-Aldeguer, J., Vrij, EJ (...) van Blitterswijk, CA., Geijsen, N. (2018). Blastocyst-like structures generated solely from stem cells. Nature. 557(7703):106-111

Basak, O., Krieger, TG., Muraro, MJ (...) Simons, BD., Clevers, H. (2018). Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy. Proc Natl Acad Sci U S A. 115(4):E610-E619

Rivron, N., Pera, M., Rossant, J (...) Munsie, M., Isasi, R. (2018). Debate ethics of embryo models from stem cells. Nature. 564(7735):183-185

Kicheva, A., Rivron, NC. (2017). Creating to understand - developmental biology meets engineering in Paris. Development. 144(5):733-736

Potier, E., Rivron, NC., Van Blitterswijk, CA., Ito, K. (2016). Micro-aggregates do not influence bone marrow stromal cell chondrogenesis. J Tissue Eng Regen Med. 10(12):1021-1032

Vrij, E., Rouwkema, J., LaPointe, V (...) Truckenmüller, R., Rivron, N. (2016). Directed Assembly and Development of Material-Free Tissues with Complex Architectures. Adv Mater. 28(21):4032-9

Vrij, EJ., Espinoza, S., Heilig, M (...) Truckenmüller, RK., Rivron, NC. (2016). 3D high throughput screening and profiling of embryoid bodies in thermoformed microwell plates. Lab Chip. 16(4):734-42

Leferink, A., Schipper, D., Arts, E (...) Moroni, L., Truckenmüller, R. (2014). Engineered micro-objects as scaffolding elements in cellular building blocks for bottom-up tissue engineering approaches. Adv Mater. 26(16):2592-9

Fennema, E., Rivron, N., Rouwkema, J., van Blitterswijk, C., de Boer, J. (2013). Spheroid culture as a tool for creating 3D complex tissues. Trends Biotechnol. 31(2):108-15

Rivron, NC., Vrij, EJ., Rouwkema, J (...) Truckenmüller, RK., van Blitterswijk, CA. (2012). Tissue deformation spatially modulates VEGF signaling and angiogenesis. Proc Natl Acad Sci U S A. 109(18):6886-91

Truckenmüller, R., Giselbrecht, S., Escalante-Marun, M (...) de Boer, J., Stamatialis, D. (2012). Fabrication of cell container arrays with overlaid surface topographies. Biomed Microdevices. 14(1):95-107

Rivron, NC., Raiss, CC., Liu, J (...) Rouwkema, J., van Blitterswijk, CA. (2012). Sonic Hedgehog-activated engineered blood vessels enhance bone tissue formation. Proc Natl Acad Sci U S A. 109(12):4413-8

Truckenmüller, R., Giselbrecht, S., Rivron, N (...) Wessling, M., van Blitterswijk, C. (2011). Thermoforming of film-based biomedical microdevices. Adv Mater. 23(11):1311-29

Rivron, NC., Rouwkema, J., Truckenmüller, R (...) De Boer, J., Van Blitterswijk, CA. (2009). Tissue assembly and organization: developmental mechanisms in microfabricated tissues. Biomaterials. 30(28):4851-8

Rivron, NC., Liu J, J., Rouwkema, J., de Boer, J., van Blitterswijk, CA. (2008). Engineering vascularised tissues in vitro. Eur Cell Mater. 15:27-40

Rouwkema, J., Rivron, NC., van Blitterswijk, CA. (2008). Vascularization in tissue engineering. Trends Biotechnol. 26(8):434-41