List of Publications

YearTitleJournalAuthors
2021Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection.EMBO Mol MedMonteil, V., Dyczynski, M., Lauschke, VM., Kwon, H., Wirnsberger, G., Youhanna, S., Zhang, H., Slutsky, AS., Hurtado Del Pozo, C., Horn, M., Montserrat, N., Penninger, JM., Mirazimi, A.
2021The oxidoreductase PYROXD1 uses NAD(P)+ as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.Mol CellAsanović, I., Strandback, E., Kroupova, A., Pasajlic, D., Meinhart, A., Tsung-Pin, P., Djokovic, N., Anrather, D., Schuetz, T., Suskiewicz, MJ., Sillamaa, S., Köcher, T., Beveridge, R., Nikolic, K., Schleiffer, A., Jinek, M., Hartl, M., Clausen, T., Penninger, J., Macheroux, P., Weitzer, S., Martinez, J.
2021RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy.NaturePaolino, M., Koglgruber, R., Cronin, SJF., Uribesalgo, I., Rauscher, E., Harreiter, J., Schuster, M., Bancher-Todesca, D., Pranjic, B., Novatchkova, M., Fededa, JP., White, AJ., Sigl, V., Dekan, S., Penz, T., Bock, C., Kenner, L., Holländer, GA., Anderson, G., Kautzky-Willer, A., Penninger, JM.
2021Ferritinophagy and ferroptosis in the management of metabolic diseases.Trends Endocrinol MetabAjoolabady, A., Aslkhodapasandhokmabad, H., Libby, P., Tuomilehto, J., Lip, GYH., Penninger, JM., Richardson, DR., Tang, D., Zhou, H., Wang, S., Klionsky, DJ., Kroemer, G., Ren, J.
2021Heme Biosynthesis mRNA Expression Signature: Towards a Novel Prognostic Biomarker in Patients with Diffusely Infiltrating Gliomas.Cancers (Basel)Mischkulnig, M., Kiesel, B., Lötsch, D., Roetzer, T., Borkovec, M., Wadiura, LI., Roessler, K., Hervey-Jumper, S., Penninger, JM., Berger, MS., Widhalm, G., Erhart, F.
2021HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.OncogeneTurgu, B., Zhang, F., El-Naggar, A., Negri, GL., Kogler, M., Tortola, L., Johnson, F., Ng, T., Li, A., Yapp, D., Lockwood, W., Martinez, D., Maris, JM., Daugaard, M., Penninger, JM., Hughes, CS., Sorensen, PH.
2021JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.Sci AdvStebbing, J., Sánchez Nievas, G., Falcone, M., Youhanna, S., Richardson, P., Ottaviani, S., Shen, JX., Sommerauer, C., Tiseo, G., Ghiadoni, L., Virdis, A., Monzani, F., Rizos, LR., Forfori, F., Avendaño Céspedes, A., De Marco, S., Carrozzi, L., Lena, F., Sánchez-Jurado, PM., Lacerenza, LG., Cesira, N., Caldevilla Bernardo, D., Perrella, A., Niccoli, L., Méndez, LS., Matarrese, D., Goletti, D., Tan, YJ., Monteil, V., Dranitsaris, G., Cantini, F., Farcomeni, A., Dutta, S., Burley, SK., Zhang, H., Pistello, M., Li, W., Romero, MM., Andrés Pretel, F., Simón-Talero, RS., García-Molina, R., Kutter, C., Felce, JH., Nizami, ZF., Miklosi, AG., Penninger, JM., Menichetti, F., Mirazimi, A., Abizanda, P., Lauschke, VM.
2021A critical relationship between bone and fat: the role of bone marrow adipose-derived RANKL in bone metabolism.EMBO RepOnji, M., Werschler, N., Penninger, J.
2021The Role of Angiotensin Converting Enzyme 2 in Modulating Gut Microbiota, Intestinal Inflammation, and Coronavirus Infection.GastroenterologyPenninger, JM., Grant, MB., Sung, JJY.
2021Modeling a human CLP1 mutation in mouse identifies an accumulation of tyrosine pre-tRNA fragments causing pontocerebellar hypoplasia type 10.Biochem Biophys Res CommunMorisaki, I., Shiraishi, H., Fujinami, H., Shimizu, N., Hikida, T., Arai, Y., Kobayashi, T., Hanada, R., Penninger, JM., Fujiki, M., Hanada, T.
2021Author Correction: Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability.Sci RepOlie, CS., van der Wal, E., Cikes, D., Maton, L., de Greef, JC., Lin, IH., Chen, YF., Kareem, E., Penninger, JM., Kessler, BM., Raz, V.
2021A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.J Exp MedHagelkruys, A., Wirnsberger, G., Stadlmann, J., Wöhner, M., Horrer, M., Vilagos, B., Jonsson, G., Kogler, M., Tortola, L., Novatchkova, M., Bönelt, P., Hoffmann, D., Koglgruber, R., Steffen, U., Schett, G., Busslinger, M., Bergthaler, A., Klein, C., Penninger, JM.
2021MKK7 deficiency in mature neurons impairs parental behavior in mice.Genes CellsShin, T., Hiraoka, Y., Yamasaki, T., Marth, JD., Penninger, JM., Kanai-Azuma, M., Tanaka, K., Kofuji, S., Nishina, H.
2021Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics.Pharmacol TherAjoolabady, A., Wang, S., Kroemer, G., Penninger, JM., Uversky, VN., Pratico, D., Henninger, N., Reiter, RJ., Bruno, A., Joshipura, K., Aslkhodapasandhokmabad, H., Klionsky, DJ., Ren, J.
2020Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM2.Biochem Biophys Res CommunInoue, M., Hada, K., Shiraishi, H., Yatsuka, H., Fujinami, H., Morisaki, I., Nishida, Y., Matsubara, E., Ishitani, T., Hanada, R., Matsumoto, M., Penninger, JM., Ihara, K., Hanada, T.
2020Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells.Nat CommunGómez-Aleza, C., Nguyen, B., Yoldi, G., Ciscar, M., Barranco, A., Hernández-Jiménez, E., Maetens, M., Salgado, R., Zafeiroglou, M., Pellegrini, P., Venet, D., Garaud, S., Trinidad, EM., Benítez, S., Vuylsteke, P., Polastro, L., Wildiers, H., Simon, P., Lindeman, G., Larsimont, D., Van den Eynden, G., Velghe, C., Rothé, F., Willard-Gallo, K., Michiels, S., Muñoz, P., Walzer, T., Planelles, L., Penninger, J., Azim, HA., Loi, S., Piccart, M., Sotiriou, C., González-Suárez, E.
2020Stepwise cell fate decision pathways during osteoclastogenesis at single-cell resolution.Nat MetabTsukasaki, M., Huynh, NC., Okamoto, K., Muro, R., Terashima, A., Kurikawa, Y., Komatsu, N., Pluemsakunthai, W., Nitta, T., Abe, T., Kiyonari, H., Okamura, T., Sakai, M., Matsukawa, T., Matsumoto, M., Kobayashi, Y., Penninger, JM., Takayanagi, H.
2020Fibroblasts as a source of self-antigens for central immune tolerance.Nat ImmunolNitta, T., Tsutsumi, M., Nitta, S., Muro, R., Suzuki, EC., Nakano, K., Tomofuji, Y., Sawa, S., Okamura, T., Penninger, JM., Takayanagi, H.
2020Human recombinant soluble ACE2 in severe COVID-19.Lancet Respir MedZoufaly, A., Poglitsch, M., Aberle, JH., Hoepler, W., Seitz, T., Traugott, M., Grieb, A., Pawelka, E., Laferl, H., Wenisch, C., Neuhold, S., Haider, D., Stiasny, K., Bergthaler, A., Puchhammer-Stoeckl, E., Mirazimi, A., Montserrat, N., Zhang, H., Slutsky, AS., Penninger, JM.
2020Reduced Prenatal Pulmonary Lymphatic Function Is Observed in Clp1K/K Embryos With Impaired Motor Functions Including Fetal Breathing Movements in Preparation of the Developing Lung for Inflation at Birth.Front Bioeng BiotechnolSzoták-Ajtay, K., Szõke, D., Kovács, G., Andréka, J., Brenner, GB., Giricz, Z., Penninger, J., Kahn, ML., Jakus, Z.