List of Publications

YearTitleJournalAuthors
2021HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.OncogeneTurgu, B., Zhang, F., El-Naggar, A., Negri, GL., Kogler, M., Tortola, L., Johnson, F., Ng, T., Li, A., Yapp, D., Lockwood, W., Martinez, D., Maris, JM., Daugaard, M., Penninger, JM., Hughes, CS., Sorensen, PH.
2021Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants.bioRxivWirnsberger, G., Monteil, V., Eaton, B., Postnikova, E., Murphy, M., Braunsfeld, B., Crozier, I., Kricek, F., Niederhöfer, J., Schwarzböck, A., Breid, H., Sanchez Jimenez, A., Bugajska-Schretter, A., Dohnal, A., Ruf, C., Gugenberger, R., Hagelkruys, A., Montserrat, N., Holbrook, MR., Oostenbrink, C., Shoemaker, RH., Mirazimi, A., Penninger, JM.
2021Development of a novel, pan-variant aerosol intervention for COVID-19.bioRxivShoemaker, RH., Panettieri, RA., Libutti, SK., Hochster, HS., Watts, NR., Wingfield, PT., Starkl, P., Pimenov, L., Gawish, R., Hladik, A., Knapp, S., Boring, D., White, JM., Lawrence, Q., Boone, J., Marshall, JD., Matthews, RL., Cholewa, BD., Richig, JW., Chen, BT., McCormick, DL., Gugensberger, R., Höller, S., Penninger, JM., Wirnsberger, G.
2021Autophagy in major human diseases.EMBO JKlionsky, DJ., Petroni, G., Amaravadi, RK., Baehrecke, EH., Ballabio, A., Boya, P., Bravo-San Pedro, JM., Cadwell, K., Cecconi, F., Choi, AMK., Choi, ME., Chu, CT., Codogno, P., Colombo, MI., Cuervo, AM., Deretic, V., Dikic, I., Elazar, Z., Eskelinen, EL., Fimia, GM., Gewirtz, DA., Green, DR., Hansen, M., Jäättelä, M., Johansen, T., Juhász, G., Karantza, V., Kraft, C., Kroemer, G., Ktistakis, NT., Kumar, S., Lopez-Otin, C., Macleod, KF., Madeo, F., Martinez, J., Meléndez, A., Mizushima, N., Münz, C., Penninger, JM., Perera, RM., Piacentini, M., Reggiori, F., Rubinsztein, DC., Ryan, KM., Sadoshima, J., Santambrogio, L., Scorrano, L., Simon, HU., Simon, AK., Simonsen, A., Stolz, A., Tavernarakis, N., Tooze, SA., Yoshimori, T., Yuan, J., Yue, Z., Zhong, Q., Galluzzi, L., Pietrocola, F.
2021Erratum to: Severe Coronavirus Disease 2019 (COVID-19) is Associated With Elevated Serum Immunoglobulin (Ig) A and Antiphospholipid IgA Antibodies.Clin Infect DisHasan Ali, O., Bomze, D., Risch, L., Brugger, SD., Paprotny, M., Weber, M., Thiel, S., Kern, L., Albrich, WC., Kohler, P., Kahlert, CR., Vernazza, P., Bühler, PK., Schüpbach, RA., Gómez-Mejia, A., Popa, AM., Bergthaler, A., Penninger, JM., Flatz, L.
2021PRDM12 Is Transcriptionally Active and Required for Nociceptor Function Throughout Life.Front Mol NeurosciKokotović, T., Langeslag, M., Lenartowicz, EM., Manion, J., Fell, CW., Alehabib, E., Tafakhori, A., Darvish, H., Bellefroid, EJ., Neely, GG., Kress, M., Penninger, JM., Nagy, V.
2021RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy.NaturePaolino, M., Koglgruber, R., Cronin, SJF., Uribesalgo, I., Rauscher, E., Harreiter, J., Schuster, M., Bancher-Todesca, D., Pranjic, B., Novatchkova, M., Fededa, JP., White, AJ., Sigl, V., Dekan, S., Penz, T., Bock, C., Kenner, L., Holländer, GA., Anderson, G., Kautzky-Willer, A., Penninger, JM.
2021The oxidoreductase PYROXD1 uses NAD(P)+ as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.Mol CellAsanović, I., Strandback, E., Kroupova, A., Pasajlic, D., Meinhart, A., Tsung-Pin, P., Djokovic, N., Anrather, D., Schuetz, T., Suskiewicz, MJ., Sillamaa, S., Köcher, T., Beveridge, R., Nikolic, K., Schleiffer, A., Jinek, M., Hartl, M., Clausen, T., Penninger, J., Macheroux, P., Weitzer, S., Martinez, J.
2021Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis.Nat MethodsKawahara, R., Chernykh, A., Alagesan, K., Bern, M., Cao, W., Chalkley, RJ., Cheng, K., Choo, MS., Edwards, N., Goldman, R., Hoffmann, M., Hu, Y., Huang, Y., Kim, JY., Kletter, D., Liquet, B., Liu, M., Mechref, Y., Meng, B., Neelamegham, S., Nguyen-Khuong, T., Nilsson, J., Pap, A., Park, GW., Parker, BL., Pegg, CL., Penninger, JM., Phung, TK., Pioch, M., Rapp, E., Sakalli, E., Sanda, M., Schulz, BL., Scott, NE., Sofronov, G., Stadlmann, J., Vakhrushev, SY., Woo, CM., Wu, HY., Yang, P., Ying, W., Zhang, H., Zhang, Y., Zhao, J., Zaia, J., Haslam, SM., Palmisano, G., Yoo, JS., Larson, G., Khoo, KH., Medzihradszky, KF., Kolarich, D., Packer, NH., Thaysen-Andersen, M.
2021JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality.Sci AdvStebbing, J., Sánchez Nievas, G., Falcone, M., Youhanna, S., Richardson, P., Ottaviani, S., Shen, JX., Sommerauer, C., Tiseo, G., Ghiadoni, L., Virdis, A., Monzani, F., Rizos, LR., Forfori, F., Avendaño Céspedes, A., De Marco, S., Carrozzi, L., Lena, F., Sánchez-Jurado, PM., Lacerenza, LG., Cesira, N., Caldevilla Bernardo, D., Perrella, A., Niccoli, L., Méndez, LS., Matarrese, D., Goletti, D., Tan, YJ., Monteil, V., Dranitsaris, G., Cantini, F., Farcomeni, A., Dutta, S., Burley, SK., Zhang, H., Pistello, M., Li, W., Romero, MM., Andrés Pretel, F., Simón-Talero, RS., García-Molina, R., Kutter, C., Felce, JH., Nizami, ZF., Miklosi, AG., Penninger, JM., Menichetti, F., Mirazimi, A., Abizanda, P., Lauschke, VM.
2021The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains.iScienceGomez-Diaz, C., Jonsson, G., Schodl, K., Deszcz, L., Bestehorn, A., Eislmayr, K., Almagro, J., Kavirayani, A., Seida, M., Fennell, LM., Hagelkruys, A., Kovarik, P., Penninger, JM., Ikeda, F.
2021A critical relationship between bone and fat: the role of bone marrow adipose-derived RANKL in bone metabolism.EMBO RepOnji, M., Werschler, N., Penninger, J.
2021Modeling a human CLP1 mutation in mouse identifies an accumulation of tyrosine pre-tRNA fragments causing pontocerebellar hypoplasia type 10.Biochem Biophys Res CommunMorisaki, I., Shiraishi, H., Fujinami, H., Shimizu, N., Hikida, T., Arai, Y., Kobayashi, T., Hanada, R., Penninger, JM., Fujiki, M., Hanada, T.
2021Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics.Pharmacol TherAjoolabady, A., Wang, S., Kroemer, G., Penninger, JM., Uversky, VN., Pratico, D., Henninger, N., Reiter, RJ., Bruno, A., Joshipura, K., Aslkhodapasandhokmabad, H., Klionsky, DJ., Ren, J.
2021Comparative proteome signatures of trace samples by multiplexed Data-Independent Acquisition.Mol Cell ProteomicsCtortecka, C., Krššáková, G., Stejskal, K., Penninger, JM., Mendjan, S., Mechtler, K., Stadlmann, J.
2021Author Correction: Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability.Sci RepOlie, CS., van der Wal, E., Cikes, D., Maton, L., de Greef, JC., Lin, IH., Chen, YF., Kareem, E., Penninger, JM., Kessler, BM., Raz, V.
2021A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.J Exp MedHagelkruys, A., Wirnsberger, G., Stadlmann, J., Wöhner, M., Horrer, M., Vilagos, B., Jonsson, G., Kogler, M., Tortola, L., Novatchkova, M., Bönelt, P., Hoffmann, D., Koglgruber, R., Steffen, U., Schett, G., Busslinger, M., Bergthaler, A., Klein, C., Penninger, JM.
2021MKK7 deficiency in mature neurons impairs parental behavior in mice.Genes CellsShin, T., Hiraoka, Y., Yamasaki, T., Marth, JD., Penninger, JM., Kanai-Azuma, M., Tanaka, K., Kofuji, S., Nishina, H.
2021Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites.EMBO JHoffmann, D., Mereiter, S., Jin Oh, Y., Monteil, V., Elder, E., Zhu, R., Canena, D., Hain, L., Laurent, E., Grünwald-Gruber, C., Klausberger, M., Jonsson, G., Kellner, MJ., Novatchkova, M., Ticevic, M., Chabloz, A., Wirnsberger, G., Hagelkruys, A., Altmann, F., Mach, L., Stadlmann, J., Oostenbrink, C., Mirazimi, A., Hinterdorfer, P., Penninger, JM.
2021Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection.EMBO Mol MedMonteil, V., Dyczynski, M., Lauschke, VM., Kwon, H., Wirnsberger, G., Youhanna, S., Zhang, H., Slutsky, AS., Hurtado Del Pozo, C., Horn, M., Montserrat, N., Penninger, JM., Mirazimi, A.