Some of the most important benefits provided to researchers at the GMI are a diverse set of core facilities and services which provide access to state-of-the-art equipment. These facilities are run by teams of experienced professionals who assist in experimental design, instrument usage, and data analysis.
Core Facilities
- BioOptics - offers flow cytometry & flow sorting on three flow cytometers, more than twenty microscopy systems including CLSM, 2P, TIRF, SIM, and LSFM, as well as assistance in image processing and analysis.
- Molecular Biology Service - provides diverse services, including Sanger sequencing, preparation of competent E. coli, 96-well format plasmid prep, instrumentation for high-throughput methods and lab automation, and runs a full-service media kitchen.
- Molecular Tool Development
- Peptide Synthesis - specializes in peptide synthesis with options for modifications or heavy isotope-labeled amino acids, and conducts purification of antibodies and other proteins, complemented by small-scale RP-HPLC purifications and TAQ purification in collaboration with MBS.
- Proteomics Facility - runs mass spectrometers and chromatography systems to enable protein separation, identification, quantification, and post-translational modification characterization, as well as offering peptide synthesis and affinity purification of antibodies.
- Proteomics Tech Hub - is at the forefront of ground-breaking research in the proteomics field, driving innovation and excellence. With a focus on single cell proteomics (SCP) and crosslinking mass spectrometry (XL-MS), the Tech Hub is pioneering two major lines of research and technological advancement. These efforts are not only crucial for ongoing collaborations at the Vienna BioCenter but also play a significant role in transferring cutting-edge know-how & methodologies to the service facility.
VBCF - Vienna BioCenter Core Facilities
- Austrian BioImaging/CMI - offers open access to imaging technologies, data services, R&D and training in biological and biomedical imaging.
- Child Care Center - advocates for career-family balance by offering childcare for children aged three months to six years for employees at the Vienna BioCenter.
- Computational Biology Training - provides practical courses in computational data analysis topics.
- Electron Microscopy - assists with diverse sample preparation techniques for on-site SEM, TEM, and cryo-EM systems.
- Histology - a fully equipped histology lab for tissue embedding, sectioning, manual and automated staining.
- Metabolomics - uses tandem mass spectrometry and chromatography for bulk and targeted metabolite profiling.
- Next Generation Sequencing - runs 3 Illumina and 1 PacBio sequencers as well as a library preparation service and assistance in the development of novel methods and protocols.
- Plant Sciences (PlantS)- operates 23 state-of-the-art growth chambers and phytotrons, including a high-throughput digital phenotyping chamber.
- Preclinical Phenotyping (pcPheno) - specializes in advanced mouse in vivo studies covering behavior tests, metabolic and cardiovascular measurements, as well as surgical services.
- Protein Technologies (proTech) - offers molecular cloning services, protein production and purification, biophysical protein characterization, and several services surrounding CRISPR/Cas9.
- Strategic Information Management
- Vienna Drosophila Resource Center (VDRC) - is a gloablly significant bioresource center that promotes scientific discoveries in Drosophila melanogaster, primarily maintaining and distributing unique transgenic Drosophila stocks and DNA resources locally and internationally.