Publications eligible for electronic reprint

This section features permalinks to publications eligible for a free-access electronic reprint service by the journal.

List of Publications

Wissel, S., Kieser, A., Yasugi, T (...) Knoblich, JA., Neumüller, RA. (2016). A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function. G3 (Bethesda). 6(8):2467-78

Esk, C., Lindenhofer, D., Haendeler, S (...) von Haeseler, A., Knoblich, JA. (2020). A human tissue screen identifies a regulator of ER secretion as a brain-size determinant. Science. 370(6519):935-941

Pașca, SP., Arlotta, P., Bateup, HS (...) Treutlein, B., Vaccarino, FM. (2022). A nomenclature consensus for nervous system organoids and assembloids. Nature. 609(7929):907-910

Schaefer, M., Shevchenko, A., Shevchenko, A., Knoblich, JA. (2000). A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila. Curr Biol. 10(7):353-62

Yasugi, T., Fischer, A., Jiang, Y., Reichert, H., Knoblich, JA. (2014). A regulatory transcriptional loop controls proliferation and differentiation in Drosophila neural stem cells. PLoS One. 9(5):e97034

Hagelkruys, A., Lagger, S., Krahmer, J (...) Knoblich, JA., Seiser, C. (2014). A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. Development. 141(3):604-616

Taubenschmid-Stowers, J., Orthofer, M., Laemmerer, A (...) Horn, M., Penninger, JM. (2023). A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors. EMBO Mol Med. 15(3):e16959

Eichmüller, OL., Corsini, NS., Vértesy, Á (...) Feucht, M., Knoblich, JA. (2022). Amplification of human interneuron progenitors promotes brain tumors and neurological defects. Science. 375(6579):eabf5546

Jüschke, C., Xie, Y., Postiglione, MP., Knoblich, JA. (2014). Analysis and modeling of mitotic spindle orientations in three dimensions. Proc Natl Acad Sci U S A. 111(3):1014-9

Knoblich, JA. (2001). Asymmetric cell division during animal development. Nat Rev Mol Cell Biol. 2(1):11-20

Knoblich, JA. (2010). Asymmetric cell division: recent developments and their implications for tumour biology. Nat Rev Mol Cell Biol. 11(12):849-60

Emery, G., Hutterer, A., Berdnik, D (...) Gaitan, MG., Knoblich, JA. (2005). Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell. 122(5):763-73

Knoblich, JA., Jan, LY., Jan, YN. (1995). Asymmetric segregation of Numb and Prospero during cell division. Nature. 377(6550):624-7

Knoblich, JA., Jan, LY., Jan, YN. (1997). Asymmetric segregation of the Drosophila numb protein during mitosis: facts and speculations. Cold Spring Harb Symp Quant Biol. 62:71-7

Betschinger, J., Mechtler, K., Knoblich, JA. (2006). Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell. 124(6):1241-53

Bian, S., Repic, M., Guo, Z (...) Krauditsch, C., Knoblich, JA. (2018). Author Correction: Genetically engineered cerebral organoids model brain tumor formation. Nat Methods. 15(9):748

Huynh, JR., Petronczki, M., Knoblich, JA., St Johnston, D. (2001). Bazooka and PAR-6 are required with PAR-1 for the maintenance of oocyte fate in Drosophila. Curr Biol. 11(11):901-6

Schober, M., Schaefer, M., Knoblich, JA. (1999). Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts. Nature. 402(6761):548-51

Akbari, OS., Bellen, HJ., Bier, E (...) Ueda, R., Wildonger, J. (2015). BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science. 349(6251):927-9

Sidhaye, J., Knoblich, JA. (2021). Brain organoids: an ensemble of bioassays to investigate human neurodevelopment and disease. Cell Death Differ. 28(1):52-67

Masselink, W., Reumann, D., Murawala, P (...) Knoblich, JA., Tanaka, EM. (2019). Broad applicability of a streamlined ethyl cinnamate-based clearing procedure. Development. 146(3)

Kreutzer, MA., Richards, JP., De Silva-Udawatta, MN (...) Lehner, CF., Bennett, KL. (1995). Caenorhabditis elegans cyclin A- and B-type genes: a cyclin A multigene family, an ancestral cyclin B3 and differential germline expression. J Cell Sci. 108 ( Pt 6):2415-24

Reichardt, I., Knoblich, JA. (2013). Cell biology: Notch recycling is numbed. Curr Biol. 23(7):R270-2

Knoblich, JA. (2006). Cell biology. Sara splits the signal. Science. 314(5802):1094-6

Barral, Y., Knoblich, J. (2008). Cell division, growth and death. Curr Opin Cell Biol. 20(6):647-9

Glotzer, M., Knoblich, JA. (1998). Cell multiplication - editorial overview. Current Opinion in Cell Biology. 10:739-41

Oliver L. Eichmüller, Nina S. Corsini, Ábel Vértesy, Theresa Scholl, Victoria-Elisabeth Gruber, Angela M. Peer, Julia Chu, Maria Novatchkova, Mercedes F. Paredes, Martha Feucht, Jürgen A. Knoblich (2020). Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis Complex BioRxiv.

Lancaster, MA., Renner, M., Martin, CA (...) Jackson, AP., Knoblich, JA. (2013). Cerebral organoids model human brain development and microcephaly. Nature. 501(7467):373-9

Luo, C., Lancaster, MA., Castanon, R (...) Knoblich, JA., Ecker, JR. (2016). Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain. Cell Rep. 17(12):3369-3384

Corsini, NS., Peer, AM., Moeseneder, P (...) Moll, I., Knoblich, JA. (2018). Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. Cell Stem Cell. 22(4):543-558.e12

Knoblich, JA., Sauer, K., Jones, L (...) Saint, R., Lehner, CF. (1994). Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell. 77(1):107-20

Lehner, CF., Ried, G., Stern, B., Knoblich, JA. (1992). Cyclins and cdc2 kinases in Drosophila: genetic analyses in a higher eukaryote. Ciba Found Symp. 170:97-109; discussion 110-4

Ayukawa, T., Akiyama, M., Mummery-Widmer, JL (...) Sasaki, T., Yamazaki, M. (2014). Dachsous-dependent asymmetric localization of spiny-legs determines planar cell polarity orientation in Drosophila. Cell Rep. 8(2):610-21

Betschinger, J., Knoblich, JA. (2004). Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates. Curr Biol. 14(16):R674-85

Tekotte, H., Berdnik, D., Török, T (...) Knoblich, JA., Davis, I. (2002). Dcas is required for importin-alpha3 nuclear export and mechano-sensory organ cell fate specification in Drosophila. Dev Biol. 244(2):396-406

Knoblich, JA., Jan, LY., Jan, YN. (1999). Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localization. Curr Biol. 9(3):155-8

Landskron, L., Bonnay, F., Burkard, TR., Knoblich, JA. (2020). DigiTAG-a RNA Sequencing Approach to Analyze Transcriptomes of Rare Cell Populations in <i>Drosophila melanogaster</i>. Bio Protoc. 10(21):e3809

Coumailleau, F., Fürthauer, M., Knoblich, JA., González-Gaitán, M. (2009). Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division. Nature. 458(7241):1051-5

Sauer, K., Knoblich, JA., Richardson, H., Lehner, CF. (1995). Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis. Genes Dev. 9(11):1327-39

Neumüller, RA., Knoblich, JA. (2009). Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer. Genes Dev. 23(23):2675-99

Petronczki, M., Knoblich, JA. (2001). DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila. Nat Cell Biol. 3(1):43-9

Berdnik, D., Knoblich, JA. (2002). Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis. Curr Biol. 12(8):640-7

Jacobs, HW., Knoblich, JA., Lehner, CF. (1998). Drosophila Cyclin B3 is required for female fertility and is dispensable for mitosis like Cyclin B. Genes Dev. 12(23):3741-51

Homem, CC., Knoblich, JA. (2012). Drosophila neuroblasts: a model for stem cell biology. Development. 139(23):4297-310

Hampoelz, B., Hoeller, O., Bowman, SK., Dunican, D., Knoblich, JA. (2005). Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins. Nat Cell Biol. 7(11):1099-105

Abdusselamoglu, MD., Landskron, L., Bowman, SK (...) Kingston, RE., Knoblich, JA. (2019). Dynamics of activating and repressive histone modifications in <i>Drosophila</i> neural stem cell lineages and brain tumors. Development. 146(23)

Homem, CCF., Steinmann, V., Burkard, TR (...) Esterbauer, H., Knoblich, JA. (2014). Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells. Cell. 158(4):874-888

Emery, G., Knoblich, JA. (2006). Endosome dynamics during development. Curr Opin Cell Biol. 18(4):407-15

Knoblich, JA. (2000). Epithelial polarity: the ins and outs of the fly epidermis. Curr Biol. 10(21):R791-4

Benetka, W., Mehlmer, N., Maurer-Stroh, S (...) Teige, M., Eisenhaber, F. (2008). Experimental testing of predicted myristoylation targets involved in asymmetric cell division and calcium-dependent signalling. Cell Cycle. 7(23):3709-19

Berger, C., Harzer, H., Burkard, TR (...) Reichert, H., Knoblich, JA. (2012). FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal. Cell Rep. 2(2):407-18

Harzer, H., Berger, C., Conder, R., Schmauss, G., Knoblich, JA. (2013). FACS purification of Drosophila larval neuroblasts for next-generation sequencing. Nat Protoc. 8(6):1088-1099

Conder, R., Knoblich, JA. (2009). Fly stem cell research gets infectious. Cell. 137(7):1185-7

Zarnescu, DC., Jin, P., Betschinger, J (...) Warren, ST., Moses, K. (2005). Fragile X protein functions with lgl and the par complex in flies and mice. Dev Cell. 8(1):43-52

Bagley, JA., Reumann, D., Bian, S., Lévi-Strauss, J., Knoblich, JA. (2017). Fused cerebral organoids model interactions between brain regions. Nat Methods. 14(7):743-751

Lancaster, MA., Knoblich, JA. (2014). Generation of cerebral organoids from human pluripotent stem cells. Nat Protoc. 9(10):2329-40

Bian, S., Repic, M., Guo, Z (...) Krauditsch, C., Knoblich, JA. (2018). Genetically engineered cerebral organoids model brain tumor formation. Nat Methods. 15(8):631-639

Mummery-Widmer, JL., Yamazaki, M., Stoeger, T (...) Dickson, BJ., Knoblich, JA. (2009). Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Nature. 458(7241):987-92

Neumüller, RA., Richter, C., Fischer, A (...) Neumüller, KG., Knoblich, JA. (2011). Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Cell Stem Cell. 8(5):580-93

Vértesy, Á., Eichmüller, OL., Naas, J (...) von Haeseler, A., Knoblich, JA. (2022). Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets. EMBO J. :e111118

Lancaster, MA., Corsini, NS., Wolfinger, S (...) Livesey, FJ., Knoblich, JA. (2017). Guided self-organization and cortical plate formation in human brain organoids. Nat Biotechnol. 35(7):659-666

Schaefer, M., Petronczki, M., Dorner, D., Forte, M., Knoblich, JA. (2001). Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system. Cell. 107(2):183-94

Hampoelz, B., Knoblich, JA. (2004). Heterotrimeric G proteins: new tricks for an old dog. Cell. 119(4):453-6

Wimmer, RA., Leopoldi, A., Aichinger, M (...) Kerjaschki, D., Penninger, JM. (2019). Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 565(7740):505-510

Eichmüller, OL., Knoblich, JA. (2022). Human cerebral organoids - a new tool for clinical neurology research. Nat Rev Neurol.

Camp, JG., Badsha, F., Florio, M (...) Huttner, WB., Treutlein, B. (2015). Human cerebral organoids recapitulate gene expression programs of fetal neocortex development. Proc Natl Acad Sci U S A. 112(51):15672-7

Lehmann, R., Lee, CM., Shugart, EC (...) Nelson, CM., Wilson, KM. (2019). Human organoids: a new dimension in cell biology. Mol Biol Cell. 30(10):1129-1137

Kim, J., Koo, BK., Knoblich, JA. (2020). Human organoids: model systems for human biology and medicine. Nat Rev Mol Cell Biol. 21(10):571-584

Corsini, NS., Knoblich, JA. (2022). Human organoids: New strategies and methods for analyzing human development and disease. Cell. 185(15):2756-2769

Bredenoord, AL., Clevers, H., Knoblich, JA. (2017). Human tissues in a dish: The research and ethical implications of organoid technology. Science. 355(6322)

Bardet, AF., Steinmann, J., Bafna, S (...) Zeitlinger, J., Stark, A. (2013). Identification of transcription factor binding sites from ChIP-seq data at high resolution. Bioinformatics. 29(21):2705-13

Li, Y., Muffat, J., Omer, A (...) Knoblich, JA., Jaenisch, R. (2017). Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell. 20(3):385-396.e3

Bulgheresi, S., Kleiner, E., Knoblich, JA. (2001). Inscuteable-dependent apical localization of the microtubule-binding protein Cornetto suggests a role in asymmetric cell division. J Cell Sci. 114(Pt 20):3655-62

Sidhaye, J., Trepte, P., Sepke, N (...) Mechtler, K., Knoblich, JA. (2023). Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids. Elife. 12

Blumer, JB., Bernard, ML., Peterson, YK (...) Knoblich, JA., Lanier, SM. (2003). Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha. J Biol Chem. 278(26):23217-20

Lovell-Badge, R., Anthony, E., Barker, RA (...) Zettler, PJ., Zhai, X. (2021). ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem Cell Reports. 16(6):1398-1408

Hyun, I., Clayton, EW., Cong, Y (...) Takahashi, J., Knoblich, JA. (2021). ISSCR guidelines for the transfer of human pluripotent stem cells and their direct derivatives into animal hosts. Stem Cell Reports. 16(6):1409-1415

Knoblich, JA. (2016). Lab-Built Brains. Sci Am. 316(1):26-31

Wirtz-Peitz, F., Knoblich, JA. (2006). Lethal giant larvae take on a life of their own. Trends Cell Biol. 16(5):234-41

Rajewsky, N., Almouzni, G., Gorski, SA (...) Vidal, M., Voet, T. (2020). LifeTime and improving European healthcare through cell-based interceptive medicine. Nature. 587(7834):377-386

Wirtz-Peitz, F., Nishimura, T., Knoblich, JA. (2008). Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization. Cell. 135(1):161-73

Schwamborn, JC., Knoblich, JA. (2008). LIS1 and spindle orientation in neuroepithelial cells. Cell Stem Cell. 2(3):193-4

Bhalerao, S., Berdnik, D., Török, T., Knoblich, JA. (2005). Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila. Curr Biol. 15(17):1583-90

Homem, CC., Reichardt, I., Berger, C., Lendl, T., Knoblich, JA. (2013). Long-term live cell imaging and automated 4D analysis of drosophila neuroblast lineages. PLoS One. 8(11):e79588

Zigman, M., Cayouette, M., Charalambous, C (...) Siderovski, DP., Knoblich, JA. (2005). Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina. Neuron. 48(4):539-45

Ballard, MS., Zhu, A., Iwai, N (...) Knoblich, JA., Hinck, L. (2015). Mammary Stem Cell Self-Renewal Is Regulated by Slit2/Robo1 Signaling through SNAI1 and mINSC. Cell Rep. 13(2):290-301

Knoblich, JA. (1997). Mechanisms of asymmetric cell division during animal development. Curr Opin Cell Biol. 9(6):833-41

Knoblich, JA. (2008). Mechanisms of asymmetric stem cell division. Cell. 132(4):583-97

Neumüller, RA., Betschinger, J., Fischer, A (...) Cohen, SM., Knoblich, JA. (2008). Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature. 454(7201):241-5

Ritzau-Reid, KI., Callens, SJP., Xie, R (...) Knoblich, JA., Stevens, MM. (2023). Microfibrous Scaffolds Guide Stem Cell Lumenogenesis and Brain Organoid Engineering. Adv Mater. :e2300305

Fededa, JP., Esk, C., Mierzwa, B (...) Knoblich, JA., Gerlich, DW. (2016). MicroRNA-34/449 controls mitotic spindle orientation during mammalian cortex development. EMBO J. 35(22):2386-2398

Shen, CP., Knoblich, JA., Chan, YM (...) Jan, LY., Jan, YN. (1998). Miranda as a multidomain adapter linking apically localized Inscuteable and basally localized Staufen and Prospero during asymmetric cell division in Drosophila. Genes Dev. 12(12):1837-46

Hutterer, A., Berdnik, D., Wirtz-Peitz, F (...) Schleiffer, A., Knoblich, JA. (2006). Mitotic activation of the kinase Aurora-A requires its binding partner Bora. Dev Cell. 11(2):147-57

Postiglione, MP., Jüschke, C., Xie, Y (...) Charalambous, C., Knoblich, JA. (2011). Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron. 72(2):269-84

Knoblich, JA. (2005). Neurobiology: getting axons going. Nature. 436(7051):632-3

Bajaj, S., Bagley, JA., Sommer, C (...) Lévi-Strauss, J., Knoblich, JA. (2021). Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration. EMBO J. :e108714

Hutterer, A., Knoblich, JA. (2005). Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs. EMBO Rep. 6(9):836-42

Knoblich, J. (2007). On the backroads to cellular asymmetry. Development (Cambridge, England). 134(24):4311-3

Lancaster, MA., Knoblich, JA. (2014). Organogenesis in a dish: modeling development and disease using organoid technologies. Science. 345(6194):1247125

Krenn, V., Bosone, C., Burkard, TR (...) Mirazimi, A., Knoblich, JA. (2021). Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly. Cell Stem Cell. 28(8):1362-1379.e7

Bonnay, F., Veloso, A., Steinmann, V (...) Zinzen, RP., Knoblich, JA. (2020). Oxidative Metabolism Drives Immortalization of Neural Stem Cells during Tumorigenesis. Cell. 182(6):1490-1507.e19

Williams, SE., Ratliff, LA., Postiglione, MP., Knoblich, JA., Fuchs, E. (2014). Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN. Nat Cell Biol. 16(8):758-69

Betschinger, J., Eisenhaber, F., Knoblich, JA. (2005). Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae. Curr Biol. 15(3):276-82

Knoblich, JA. (2005). Pins for spines. Nat Cell Biol. 7(12):1157-8

Homem, CC., Repic, M., Knoblich, JA. (2015). Proliferation control in neural stem and progenitor cells. Nat Rev Neurosci. 16(11):647-59

Bonnay, F., Knoblich, JA. (2020). Prospero Phase-Separating the Way to Neuronal Differentiation. Dev Cell. 52(3):251-252

Schaefer, M., Knoblich, JA. (2001). Protein localization during asymmetric cell division. Exp Cell Res. 271(1):66-74

Lancaster, MA., Corsini, NS., Wolfinger, S (...) Livesey, FJ., Knoblich, JA. (2018). Publisher Correction: Guided self-organization and cortical plate formation in human brain organoids. Nat Biotechnol. 36(10):1016

Rajewsky, N., Almouzni, G., Gorski, SA (...) Vidal, M., Voet, T. (2021). Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine. Nature. 592(7852):E8

Jüschke, C., Knoblich, JA. (2008). Purification of Drosophila protein complexes for mass spectrometry. Methods Mol Biol. 420:347-58

Mayer, B., Emery, G., Berdnik, D., Wirtz-Peitz, F., Knoblich, JA. (2005). Quantitative analysis of protein dynamics during asymmetric cell division. Curr Biol. 15(20):1847-54

Bassett, DS., Cullen, KE., Eickhoff, SB (...) Sur, M., Ueda, HR. (2020). Reflections on the past two decades of neuroscience. Nat Rev Neurosci. 21(10):524-534

Kraut, R., Chia, W., Jan, LY., Jan, YN., Knoblich, JA. (1996). Role of inscuteable in orienting asymmetric cell divisions in Drosophila. Nature. 383(6595):50-5

Jafar-Nejad, H., Andrews, HK., Acar, M (...) Knoblich, JA., Bellen, HJ. (2005). Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors. Dev Cell. 9(3):351-63

Renner, M., Lancaster, MA., Bian, S (...) Chung, K., Knoblich, JA. (2017). Self-organized developmental patterning and differentiation in cerebral organoids. EMBO J. 36(10):1316-1329

Hutterer, A., Betschinger, J., Petronczki, M., Knoblich, JA. (2004). Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. Dev Cell. 6(6):845-54

Subramanian, A., Prokop, A., Yamamoto, M (...) Knoblich, JA., Volk, T. (2003). Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction. Curr Biol. 13(13):1086-95

Li, C., Fleck, JS., Martins-Costa, C (...) Treutlein, B., Knoblich, JA. (2023). Single-cell brain organoid screening identifies developmental defects in autism. Nature. 621(7978):373-380

Rhyu, MS., Knoblich, JA. (1995). Spindle orientation and asymmetric cell fate. Cell. 82(4):523-6

Lancaster, MA., Knoblich, JA. (2012). Spindle orientation in mammalian cerebral cortical development. Curr Opin Neurobiol. 22(5):737-46

Eroglu, E., Burkard, TR., Jiang, Y (...) Reichert, H., Knoblich, JA. (2014). SWI/SNF complex prevents lineage reversion and induces temporal patterning in neural stem cells. Cell. 156(6):1259-1273

Knoblich, JA., Lehner, CF. (1993). Synergistic action of Drosophila cyclins A and B during the G2-M transition. EMBO J. 12(1):65-74

Vishnu, S., Hertenstein, A., Betschinger, J (...) Gert de Couet, H., Fischbach, KF. (2006). The adaptor protein X11Lalpha/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila. Dev Biol. 289(2):296-307

Landskron, L., Steinmann, V., Bonnay, F (...) Reichert, H., Knoblich, JA. (2018). The asymmetrically segregating lncRNA cherub is required for transforming stem cells into malignant cells. Elife. 7

Sparmann, A., Xie, Y., Verhoeven, E (...) Knoblich, JA., van Lohuizen, M. (2013). The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation. EMBO J. 32(11):1598-612

Gallagher, CM., Knoblich, JA. (2006). The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila. Dev Cell. 11(5):641-53

Mauri, F., Reichardt, I., Mummery-Widmer, JL., Yamazaki, M., Knoblich, JA. (2014). The conserved discs-large binding partner Banderuola regulates asymmetric cell division in Drosophila. Curr Biol. 24(16):1811-25

Knoblich, JA. (2001). The Drosophila nervous system as a model for asymmetric cell division. Symp Soc Exp Biol. (53):75-89

Bowman, SK., Neumüller, RA., Novatchkova, M., Du, Q., Knoblich, JA. (2006). The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division. Dev Cell. 10(6):731-42

Frise, E., Knoblich, JA., Younger-Shepherd, S., Jan, LY., Jan, YN. (1996). The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage. Proc Natl Acad Sci U S A. 93(21):11925-32

Khazaei, MR., Bunk, EC., Hillje, AL (...) Young, P., Schwamborn, JC. (2011). The E3-ubiquitin ligase TRIM2 regulates neuronal polarization. J Neurochem. 117(1):29-37

Berdnik, D., Török, T., González-Gaitán, M., Knoblich, JA. (2002). The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev Cell. 3(2):221-31

Huch, M., Knoblich, JA., Lutolf, MP., Martinez-Arias, A. (2017). The hope and the hype of organoid research. Development. 144(6):938-941

Hagelkruys, A., Horrer, M., Taubenschmid-Stowers, J (...) Knoblich, JA., Penninger, JM. (2022). The HUSH complex controls brain architecture and protocadherin fidelity. Sci Adv. 8(44):eabo7247

Knoblich, JA., Jan, LY., Jan, YN. (1997). The N terminus of the Drosophila Numb protein directs membrane association and actin-dependent asymmetric localization. Proc Natl Acad Sci U S A. 94(24):13005-10

Bock, C., Boutros, M., Camp, JG (...) Treutlein, B., Vries, RGJ. (2021). The Organoid Cell Atlas. Nat Biotechnol. 39(1):13-17

Goulas, S., Conder, R., Knoblich, JA. (2012). The Par complex and integrins direct asymmetric cell division in adult intestinal stem cells. Cell Stem Cell. 11(4):529-40

Betschinger, J., Mechtler, K., Knoblich, JA. (2003). The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. Nature. 422(6929):326-30

Speicher, S., Fischer, A., Knoblich, J., Carmena, A. (2008). The PDZ protein Canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors. Curr Biol. 18(11):831-7

Xie, Y., Jüschke, C., Esk, C., Hirotsune, S., Knoblich, JA. (2013). The phosphatase PP4c controls spindle orientation to maintain proliferative symmetric divisions in the developing neocortex. Neuron. 79(2):254-65

Abramczuk, MK., Burkard, TR., Rolland, V (...) Reichert, H., Knoblich, JA. (2017). The splicing co-factor Barricade/Tat-SF1 is required for cell cycle and lineage progression in <i>Drosophila</i> neural stem cells. Development. 144(21):3932-3945

Abdusselamoglu, MD., Eroglu, E., Burkard, TR., Knoblich, JA. (2019). The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop. Elife. 8

Marchetti, G., Reichardt, I., Knoblich, JA., Besse, F. (2014). The TRIM-NHL protein Brat promotes axon maintenance by repressing src64B expression. J Neurosci. 34(41):13855-64

Schwamborn, JC., Berezikov, E., Knoblich, JA. (2009). The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell. 136(5):913-25

Reichardt, I., Bonnay, F., Steinmann, V (...) Meister, G., Knoblich, JA. (2018). The tumor suppressor Brat controls neuronal stem cell lineages by inhibiting Deadpan and Zelda. EMBO Rep. 19(1):102-117

Bowman, SK., Rolland, V., Betschinger, J (...) Emery, G., Knoblich, JA. (2008). The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila. Dev Cell. 14(4):535-46

Richter, C., Oktaba, K., Steinmann, J., Müller, J., Knoblich, JA. (2011). The tumour suppressor L(3)mbt inhibits neuroepithelial proliferation and acts on insulator elements. Nat Cell Biol. 13(9):1029-39

Wissel, S., Harzer, H., Bonnay, F (...) Neumüller, RA., Knoblich, JA. (2018). Time-resolved transcriptomics in neural stem cells identifies a v-ATPase/Notch regulatory loop. J Cell Biol. 217(9):3285-3300

Falk, S., Bugeon, S., Ninkovic, J (...) Knoblich, JA., Götz, M. (2017). Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding. Neuron. 93(4):777-791.e3

Corsini, NS., Knoblich, JA. (2018). Tracing Stem Cell Division in Adult Neurogenesis. Cell Stem Cell. 22(2):143-145

Jüschke, C., Dohnal, I., Pichler, P (...) Mechtler, K., Knoblich, JA. (2013). Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation. Genome Biol. 14(11):r133

Neumüller, RA., Knoblich, JA. (2009). Wicked views on stem cell news. Nat Cell Biol. 11(6):678-9

Landskron, L., Knoblich, JA. (2016). You Are What You Eat: Linking Metabolic Asymmetry and Cell Fate Choice. Dev Cell. 37(3):206-8