Red2Onco, an innovative genetic mouse model, allows to detect the very initial steps that lead to cancer development. Red2Onco’s multi-colour labelling system allows to trace intestinal tumour development after the first oncogenic hit at the single…

Self-organizing heart organoids developed at IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – are also effective injury- and in vitro congenital disease models. These “cardioids” may revolutionize research into…

How the immune system adapts to pregnancy has puzzled researchers for decades. An international team of researchers, including scientists from IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – has now discovered that…

Researchers from the laboratory of Jürgen Knoblich at IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – developed CRISPR-LICHT, a revolutionary technology that allows genetic screens in human tissues such as brain…

Proper folding of extremely long chromosomal DNA molecules is crucial for the correct functioning of the cell. Scientists from the Gerlich lab at IMBA – Institute of Molecular Biotechnology of the Austrian Academy of Sciences – developed a…

Despite all recent progress, cancer remains one of the deadliest human diseases. In a new publication that appeared in the journal Cell, researchers from Jürgen Knoblich's lab at IMBA – Institute of Molecular Biotechnology of the Austrian Academy of…

A team of researchers, spearheaded by the Gerlich lab at IMBA, has uncovered how cells remove unwanted components from the nucleus following mitosis. The results, published in the journal Nature, stem from a fruitful collaboration between the Gerlich…