Nick Irwin


Hehenberger, Boscaro, James ER, et al. (2023) New parabasalian symbionts Snyderella spp. and Daimonympha gen. nov. from South American Rugitermes termites and the parallel evolution of a cell with a rotating “head”. J Eukaryot Microbiol 70(5):e12987

Holt CC, Hehenberger E, Tikhonenkov, et al. (2023) Multiple parallel origins of parasitic marine alveolates. Nat Commun 14(1): 7049

Irwin NAT and Richards TA (2023). Self-assembling viral histones unravel the early evolution of the nucleosome. bioRxiv:2023.09.20.558576.

Lapinska U, Glover G, Kahveci Z, et al. (2023) Systematic comparison of unilamellar vesicles reveals that archaeal core lipid membranes are more permeable than bacterial ones. PLoS Biol 21(4): e3002048

Milner DS, Javier Galindo L, Irwin NAT, et al. (2023) Transporter proteins as ecological assets and features of microbial eukaryotic pangenomes. Annu Rev Microbiol 77:45-66.

Picchianti L, Sanchez de Medina Hernandez V, ..., Dagdas Y (2023) Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and autophagy. EMBO J 42(10):e112053 preprint bioRxiv:2022.04.26.489478.


Alacid E, Irwin NAT, Smilansky V, et al.(2022) A diversified and seggregated mRNA spliced-leader system in the parasitic Perkinsozoa. Open Biol 12(8): 220126.

Boscaro V, Holt CC, Van Steenkiste NWL, et al. (2022) Microbiomes of microscopic marine invertebrates do not reveal signatures of phylosymbiosis. Nat Microbiol 7(6): 810-9.

Boscaro V, Syberg-Olsen MJ, Irwin NAT, et al. (2022) All essential endosymbionts of the ciliate Euplotes are cyclically replaced. Curr Biol 32(15):R826-7.

Holt, CC, Boscaro V, Van Steenkiste NWL, et al. (2022) Microscopic marine invertebrates are reservoirs for cryptic and diverse protists and fungi. Microbiome 10(1):161.

Irwin NAT, Pittis AA, Richards TA, et al. (2022). Systematic evaluation of horizontal gene transfer between eukaryotes and viruses. Nat Microbiol 7(2):327–36.


Irwin NAT, Pittis AA, Mathur V, et al. (2021) The functional diversity and evolution of motile DNA replication systems in ciliates. Curr Biol 31(1):66-76.

Irwin NAT, Twynstra CS, Mathur V, et al. (2021). The molecular phylogeny of Chionaster nivalis reveals a novel order of psychrophilic and globally distributed Tremellomycetes (Fungi, Basidiomycota). PLoS One 16(3): e0247594.

Kwong W, Irwin NAT, Mathur V, Net al. (2021) Taxonomy of the apicomplexan symbionts of coral, including Corallicolida ord. nov., reassignment of the genus Gemmocystis, and description of new species Corallicola aquarius gen. nov. sp. nov. and Anthozoaphila gnarlus gen. nov. sp. nov. J Eukaryot Microbiol 68:e12852.

Mathur V, Kwong WK, Husnik F, et al. (2021) Phylogenomics identifies a new major subgroup of apicomplexans, Marosporida class nov., with extreme apicoplast genome reduction. Genome Biol Evol 13(2):evaa244.

Singh RA, Boscaro V, James ER, et al. (2021) Characterization of new cristamonad species from kalotermid termited including a novel genus, Runanympha. Sci Rep 11(1):7270.


Faktorová D, Nisbet RER, Fernández Robledo JA, et al. (2020) Genetic tool development in marine protists: Emerging model organisms for experimental cell biology. Nat Methods 17(5):481-94.

Fukuda K, Cooney EC, Irwin NAT, et al. (2020) High-efficiency transformation of the chlorarachniophyte Amorphochlora amoebiformis by electroporation. Algal Research 48:101903.

Wideman J, Monier A, Rodriguez-Martinez R, et al. (2020) Unexpected mitochondrial genome diversity revealed by targeted single-cell genomics. Nat Microbiol 5(1):154-15


Boscaro V, Syberg-Olsen MJ, Irwin NAT, et al. (2019). What can environmental sequences tell us about the distribution of low-rank taxa? The case of Euplotes (Ciliophora, Spirotrichea), including a description of Euplotes enigma sp. nov. J Eukaryot Microbiol 66(2):281-93.

Irwin NAT and Keeling PJ (2019) Extensive reduction of the nuclear pore complex in nucleomorphs. Genome Biol Evol 11(3):678-87.

Irwin NAT, Tikhonenkov D, Hehenberger E, et al. (2019). Phylogenomics supports the monophyly of the Cercozoa. Mol Phylogenet Evol 130:416-23.

Mathur V, Kolisko M, Hehenberger E, et al. (2019) Multiple independent origins of apicomplexan-like parasites. Curr Biol 29(17):2936-41.

Needham DM, Yoshizawa S, Hosaka T, et al. (2019) A distinct lineage of giant viruses brings a rhodopsin photosystem to unicellular marine predators. Proc Natl Acad Sci USA 116(41):20574-83.


Irwin NAT, Martin BJE, Young BP, et al. (2018) Viral proteins as a potential driver of histone depletion in dinoflagellates. Nat Commun 9(1):1535.


Boscaro V, James ER, Fiorito R, et al. (2017) Molecular characterization and phylogeny of four new Trichonympha(Parabasalia,Trichonymphea) species from lower termite hindguts. Int J Syst Evol Microbiol 67(9):3570-5.

del Campo J, James ER, FioRito R, et al. (2017). Pseudotrichonympha leei sp. nov., Pseudotrichonympha lifsoni sp. nov., and Pseudotrichonympha pearti sp. nov., parabasalian flagellates from the hindguts of rhinotermatid termites. Sci Rep 7(1):16349.

Irwin NAT, Sabetrasekh M, and Lynn DH (2017) Diversification and phylogenetics of mobilid Peritrichs (Ciliophora) with description of Urceolaria parakorschelti sp. nov. Protist 168(4):481-493

Lawrence M, Coutin N, Choi JK, et al. (2017) Histone acetylation, not stoichiometry, regulates linker histone binding in S. cerevisiae. Genetics 207(1):347-55.


Syberg-Olsen MJ, Irwin NAT, Vannini C, et al. (2016) Biogeography and character evolution of the ciliate genus Euplotes (Spirotrichea, Euplotia), with description of Euplotes curdsi sp. nov. PLoS One. 11(11):e0165442.

McBurney KL, Leung A, Choi J, et al. (2016) Divergent residues within histone H3 dictate a unique chromatin structure in Saccharomyces cerevisiae. Genetics. 202(1):341-9

Irwin NAT and Lynn DH (2015) Molecular phylogeny of Mobilid and Sessilid ciliates symbiotic in Eastern Pacific limpets (Mollusca: Patellogastropoda). J Eukaryot Microbiol 62(4):543-52.

Group members

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