Sabrina VILLAR PAZOS

Sabrina VILLAR PAZOS

Postdoc
Research Grade

+43 1 79044/4696
sabrina.villar(at)imba.oeaw.ac.at

https://www.linkedin.com/in/sabrina-villar-pazos-1ba012150/

Former and Current Positions

2024- present - Postdoctoral Researcher – Sofia Grade's lab, IMBA

2022-2023 - Senior Research Assistant – Sofia Grade's lab, IMBA

2018-2022 - Postdoctoral Associate – University of Pittsburgh (Pennsylvania, United States)

2014 - Visiting scholar – Université Libre de Bruxelles (Brussels, Belgium)

2013-2017 - Graduate Researcher (PhD student) – Universidad Miguel Hernández de Elche (Alicante, Spain)

2011 - 2012 - Graduate Researcher (Master student) – Universidad de Santiago de Compostela (A Coruña, Spain)

Research Projects

Neurodevelopmental component of Huntington’s disease (HD).

My current research focuses on identifying very early alterations in the developing connectivity of the striatum in Huntington’s disease (HD). My work will help to elucidate how these neurodevelopmental anomalies may contribute to the disease progression.

S Villar-Pazos, L Thomas, Y Yang, K Chen, JB Lyles, BJ Deitch, J Ochaba, K Ling, B Powers, S Gingras, HB Kordasiewicz, MJ Grubisha, YH Huang. G Thomas. (2023) Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy. Nat Commun. 2023 Oct 17;14(1):6547. doi: 10.1038/s41467-023-42176-8.
E Sala, C Vived, J Luna, NA Saavedra-Ávila, U Sengupta, AR Castaño, S Villar-Pazos, L Haba, J Verdaguer, AB Ropero, T Stratmann, J Pizarro, M Vázquez-Carrera, A Nadal, JM Lahti, C Mora. (2021). CDK11 promotes cytokine-induced apoptosis in pancreatic beta cells independently of glucose concentration and is regulated by inflammation in the NOD mouse model. Front Immunol., Feb 10;12:634797. doi: 10.3389/fimmu.2021.634797.
J Martinez-Pinna, L Marroqui, A Hmadcha, J Lopez-Beas, S Soriano, S Villar-Pazos, P Alonso-Magdalena, RS Dos Santos, I Quesada, F Martin, B Soria, JA Gustafsson, A Nadal. (2019). Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells. Diabetologia. Sep;62(9):1667-1680. doi: 10.1007/s00125-019-4925-y.
S Soriano, M Castellano-Muñoz, A Rafacho, P Alonso-Magdalena, L Marroqui, A. Ruiz-Pino, E Bru-Tarí, B Merino, E Irles, M Bello, P Iborra, S Villar-Pazos, JF Vettorazzi, E. Montanya, RM Luque, A Nadal, I Quesada. (2019). Cortistatin regulates glucose-induced electrical activity and insulin secretion in mouse pancreatic beta-cells. Moll Cell Endocrinol Jan 5; 479:123-132. doi: 10.1016/j.mce.2018.09.009.
A Nadal, E Fuentes, C Ripoll, S Villar-Pazos, M Castellano-Muñoz, S Soriano, J Martinez-Pinna, I Quesada, P Alonso-Magdalena. (2018). Extranuclear-initiated estrogenic actions of endocrine disrupting chemicals: Is there toxicology beyond Paracelsus? J Steroid Biochem Mol Biol. Feb 2018; 176: 16-22. doi: 10.1016/j.jsbmb.2017.01.014
S Villar-Pazos, J Martinez-Pinna, M Castellano-Muñoz, P Alonso-Magdalena, L Marroqui, I Quesada, JA Gustafsson, A Nadal. (2017). Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca2+ entry in mouse pancreatic β-cells. Sci Rep. Sep 18; 7(1): 11770. doi: 10.1038/s41598-017-11995-3
M García-Arévalo, P Alonso-Magdalena, JM Servitja, T Boronat-Belda, B Merino, S Villar-Pazos, G Medina-Gómez, A Novials, I Quesada, A Nadal. (2016). Maternal exposure to bisphenol-A during pregnancy increases pancreatic β-Cell growth during early life in male mice offspring. Endocrinology. Nov: 157 (11): 4158-4171. doi: 10.1210/en.2016-1390
E Irles, P Ñeco, M Lluesma, S Villar-Pazos, JC Santos-Silva, JF Vettorazzi, P Alonso-Magdalena, EM Carneiro, AC Boschero, A Nadal. I Quesada. (2015). Enhanced glucose-induced intracellular signaling promotes insulin hypersecretion: pancreatic beta-cell functional adaptations in a model of genetic obesity and prediabetes. Mol Cell Endocrinol. Mar 15: 404:46-55. doi: 10.1016/j.mce.2015.01.033

Name	Purpose	Storage duration	Type	Provider
CookieConsent	Remembers your consent to the use of cookies.	1 year	HTML	Web Consent
fe_typo_user	Assigns your browser to a session on the server. This only affects the content you see and is not evaluated or processed by us	-	HTTP	Web User

Name	Purpose	Storage duration	Type	Provider
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_pk_ses	Short-term cookie to save temporary data from the visit.	30 minutes	HTML	Matomo-ses
_pk_cvar	Short-term cookie to save temporary data from the visit.	30 minutes	HTML	Matomo-cvar
_pk_hsr	Short lived cookie used to temporarily store data for the visit.	30 minutes	HTML	Matomo

Name	Purpose	Storage duration	Type	Provider
YouTube	A connection to YouTube will be established to view videos.	-	Connection	YouTube
SoundCloud	A connection to SoundCloud will be established to play audio files.	-	Connection	SoundCloud
Twitter	A connection to Twitter will be established to display tweets.	-	missing translation: type.	Twitter
_cs_c	Indicates whether the user has consented to ContentSquare tracking.	394 days	missing translation: type.	Spotify (ContentSquare)
_cs_id	Stores a unique user ID for ContentSquare session analysis.	394 days	missing translation: type.	Spotify (ContentSquare)
_ga	Used to distinguish users.	400 days	missing translation: type.	Google Analytics
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_ga_S0T2DJJFZM	Used by Google Analytics to persist session state.	399 days	missing translation: type.	Google Analytics
_ga_ZWG1NSHWD8	Used by Google Analytics to persist session state.	400 days	missing translation: type.	Google Analytics
_ga_ZWRF3NLZJZ	Used by Google Analytics to persist session state.	400 days	missing translation: type.	Google Analytics
_gid	Used to distinguish users.	1 days	missing translation: type.	Google Analytics
_ScCbts	Stores temporary session or playback preferences.	6 days	missing translation: type.	Spotify
_scid	Spotify advertising ID used for analytics and retargeting.	395 days	missing translation: type.	Spotify
_scid_r	Spotify advertising ID used for analytics and retargeting.	395 days	missing translation: type.	Spotify
eupubconsent-v2	Stores the IAB Transparency & Consent Framework string.	364 days	missing translation: type.	IAB / Spotify
OptanonAlertBoxClosed	Saves the state of your data protection consent.	364 days	missing translation: type.	OneTrust
OptanonConsent	Saves the state of your data protection consent.	365 days	missing translation: type.	OneTrust
sp_adid	Spotify advertising identifier.	365 days	missing translation: type.	Spotify
sp_landing	Tracks which page the user landed on within Spotify.	1 days	missing translation: type.	Spotify
sp_m	Stores the user’s market region (Spotify).	399 days	missing translation: type.	Spotify
sp_t	Session token used for Spotify playback and access.	365 days	missing translation: type.	Spotify

Sofia Grade

Sabrina VILLAR PAZOS

Sabrina VILLAR PAZOS

Former and Current Positions

Research Projects

Contact

Vienna BioCenter

Links