There are a number of surveillance mechanisms that function at different stages of the mRNA biogenesis pathway. Madalena Reimão-Pinto and Raphael Manzenreither, both PhD students in the Ameres Lab, have identified an enzyme complex, that was found to play a key role in cytoplasmic RNA quality control. 

The TRUMP complex does not refer to the current pre-electoral craze in the US, but to cytoplasmic terminal RNA uridylation-mediated processing. 

TRUMP regulates the maturation of microRNAs in flies and targets aberrant RNA polymerase III transcripts for degradation – it acts as a cytoplasmic RNA quality control system.

The identification of this newly identified enzyme complex sheds light on the emerging role of post-transcriptional RNA modifications and deepens the understanding of cytoplasmic RNA surveillance pathways.

The original paper “Molecular basis for cytoplasmic RNA surveillance by uridylation?triggered decay in Drosophila”, is now published online in the EMBO Journal.
http://emboj.embopress.org/content/early/2016/10/11/embj.201695164