Sven Klumpe is a structural cell biologist that studies mobile genetic elements by cryo-electron tomography, a powerful imaging approach that allows scientists to visualize molecular structures inside cells at high resolution. His work combines advanced microscopy with technology development to make these methods more accessible and automated at the IMP and IMBA.

The project funded by the Chan Zuckerberg Initiative’s Biohub supports the development of fibsem-os, an open-source, community-driven software platform designed to simplify and unify the control of focused ion beam–scanning electron microscopes (FIB-SEM). FIB-SEMs are used to prepare thin sections of cells, opening windows into cellular ultrastructure at high resolution. The software aims to make complex microscopy workflows easier to use, more reproducible, and available across different microscope manufacturers.

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