The genetic information is encoded in very long DNA molecules, which adopt specific three-dimensional organization inside cells to support various functions. Understanding how the three-dimensional organization of DNA relates to the binding of…

The Austrian Science Fund FWF has awarded a prestigious ESPRIT grant to scientists from the Proteomics Tech Hub at the Vienna BioCenter. Julia Bubis and Karl Mechtler will study the single-cell proteomics of human blastoids, early stage embryos.

Cohesin, a ring-shaped protein complex, tethers the two DNA copies contained in each replicated chromosome such that they can be properly moved during cell division. A subset of cohesin complexes, known for its ability to extrude DNA loops, also…

Scientists have known for decades that genes can be transferred from one species to another, both in animals and plants. However, the mechanism of how such an unlikely event occurs remained unknown. Now, researchers from Alejandro Burga’s lab at the…

Over two days, more than 400 guests celebrated IMBA’s scientific contributions. From chromosomes to RNA, from organoids to the understanding of important disease mechanisms: the breadth of scientific achievements by scientists at IMBA were put…

During a region-wide event on April 27, IMBA welcomed a cohort of female secondary school students from Vienna to learn about career paths for professions in the natural sciences.

Karl Mechtler, Head of the Proteomics Tech Hub at IMP, IMBA, and GMI, is the first Austrian scientist to receive the prestigious Juan Pablo Albar Proteome Pioneer Award from the European Proteomics Association.

Muscle degeneration, the most prevalent cause of frailty in hereditary diseases and aging, could be caused by a deficiency in one key enzyme in a lipid biosynthesis pathway. Researchers at the Institute of Molecular Biotechnology (IMBA) of the…

Researchers at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences will be awarded the Alfred Hauptmann Prize at the “Epilepsie 2023” meeting in Berlin. Jürgen Knoblich, Nina Corsini and Oliver Eichmüller receive the…

After fertilization, the genome of the embryo is transcriptionally inactive and maternally deposited RNA and proteins perform cellular functions. During a process called maternal-to-zygotic transition (MZT) the zygotes’ own transcriptional program is…