YearTitleJournalAuthors
2021The Trithorax group protein ASH1 requires a combination of BAH domain and AT hooks, but not the SET domain, for mitotic chromatin binding and survival.ChromosomaSteffen, PA., Altmutter, C., Dworschak, E (...) Kockmann, T., Ringrose, L.
2020Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target.Intensive Care MedZhang, H., Penninger, JM., Li, Y., Zhong, N., Slutsky, AS.
2020Parallel PRC2/cPRC1 and vPRC1 pathways silence lineage-specific genes and maintain self-renewal in mouse embryonic stem cells.Sci AdvZepeda-Martinez, JA., Pribitzer, C., Wang, J (...) Zuber, J., Bell, O.
2020Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles.Nat MethodsMichlits, G., Jude, J., Hinterndorfer, M (...) Zuber, J., Elling, U.
2020ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL.ElifeWutz, G., Ladurner, R., St Hilaire, BG (...) Lieberman-Aiden, E., Peters, JM.
2020AMPK leads to phosphorylation of the transcription factor Nrf2, tuning transactivation of selected target genes.Redox BiolMatzinger, M., Fischhuber, K., Pölöske, D., Mechtler, K., Heiss, EH.
2020Cardioids reveal self-organizing principles of human cardiogenesisBioRxivPablo Hofbauer, Stefan Jahnel, Nora Papai, Magdalena Giesshammer, Mirjam Penc, Katherina Tavernini, Nastasja Grdseloff, Christy Meledeth, Alison Deyett, Clara Schmidt, Claudia Ctortecka, Šejla Šalic, Maria Novatchkova, Sasha Mendjan
2020Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis ComplexBioRxivOliver L. Eichmüller, Nina S. Corsini, Ábel Vértesy, Theresa Scholl, Victoria-Elisabeth Gruber, Angela M. Peer, Julia Chu, Maria Novatchkova, Mercedes F. Paredes, Martha Feucht, Jürgen A. Knoblich
2020Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells.Emerg Microbes InfectAppelberg, S., Gupta, S., Svensson Akusjärvi, S (...) Mirazimi, A., Neogi, U.
2020Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos.Mol CellDu, Z., Zheng, H., Kawamura, YK (...) Peters, AHFM., Xie, W.
2020The biophysical, molecular, and anatomical landscape of pigeon CRY4: A candidate light-based quantal magnetosensor.Sci AdvHochstoeger, T., Al Said, T., Maestre, D (...) Schleicher, E., Keays, DA.
2020Oxidative Metabolism Drives Immortalization of Neural Stem Cells during Tumorigenesis.CellBonnay, F., Veloso, A., Steinmann, V (...) Zinzen, RP., Knoblich, JA.
2020Conformation of sister chromatids in the replicated human genome.NatureMitter, M., Gasser, C., Takacs, Z (...) Micura, R., Gerlich, DW.
2020RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.EMBO JSpit, M., Fenderico, N., Jordens, I (...) Vermeulen, M., Maurice, MM.
2020Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling.EMBO JFennell, LM., Gomez Diaz, C., Deszcz, L (...) Penninger, J., Ikeda, F.
2020The H3 histone chaperone NASPSIM3 escorts CenH3 in Arabidopsis.Plant JLe Goff, S., Keçeli, BN., Jeřábková, H (...) Probst, AV., Lermontova, I.
2020Fibroblasts as a source of self-antigens for central immune tolerance.Nat ImmunolNitta, T., Tsutsumi, M., Nitta, S (...) Penninger, JM., Takayanagi, H.
2020Stepwise cell fate decision pathways during osteoclastogenesis at single-cell resolution.Nat MetabTsukasaki, M., Huynh, NC., Okamoto, K (...) Penninger, JM., Takayanagi, H.
2020Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells.Nat CommunGómez-Aleza, C., Nguyen, B., Yoldi, G (...) Sotiriou, C., González-Suárez, E.
2020Structure-function analysis of microRNA 3'-end trimming by Nibbler.Proc Natl Acad Sci U S AXie, W., Sowemimo, I., Hayashi, R (...) Ameres, SL., Patel, DJ.