Biochemical and Clinical Aspects of Pteridines. Cancer - Immunology - Metabolic Diseases : : Proceedings . Winter Workshop on Pteridines. / Vol. 4, : February 23–March 2, 1985, St. Christoph, Arlberg, Austria / / ed. by H. Ch. Curtius, Helmut Wachter, W. Pfleiderer.

• Superior document: Title is part of eBook package: De Gruyter DGBA Reference Works <1990
• MitwirkendeR: Abou-Donia, Martha M.,; Adolf, G.,; Andondonskaja-Renz, B.,; Balestrieri, A.,; Bauer, H.,; Bichler, Alfred,; Bienhaus, G.,; Blair, J.A.,; Blair, John A.,; Blau, Nenad,; Bollbach, R.,; Brown, G.M.,; Cabras, F.,; Cappai, G.,; Casula, D.,; Clayton, P. T.,; Conrad, F.,; Cooper, Bernard A.,; Cotton, Richard G.H.,; Cremer-Bartels, G.,; Curtius, H.-Ch.,; Curtius, Hans-Christoph,; Daniels, Alejandro J.,; Deutsch, E.,; Dhondt, J.L.,; Dhondt, Jean-Louis,; Dietrich, M.,; Diliberto, Emanuel,; Duch, David S.,; Dudczak, R.,; Ebner, B.,; Edelstein, Mark P.,; Erfle, V.,; Farci, A.M.G.,; Fink, M.,; Fischer, M.,; Fowler, Kerry,; Frischauf, H.,; Fuch, Dietmar,; Fuchs, D.,; Fuchs, Dietmar,; Fuith, Lothar C.,; Gadow, A.,; Garau, V.L.,; Ghisla, Sandro,; Goebel, F.-D.,; Gottlieb, Raphael,; Gratwohl, A.,; Guest, A.E.,; Hase, Y.,; Hase, Yutaka,; Hausen, A.,; Hausen, Arno,; Hayte, J.M.,; Heales, S.J.R.,; Hehlmann, R.,; Heintel, Dorothee,; Hetzel, Heinz,; Hien, P.,; Hinterberger, W.,; Horstmann, R.D.,; Howells, D. W.,; Huber, Ch.,; Huber, Christoph,; Huber, J.F.K.,; Hyland, K.,; Isshiki, G.,; Isshiki, Gen,; J.F.K., Huber,; Judmaier, G.,; Kalhs, P.,; Kern, P.,; Knapp, S.,; Kodama, Y.,; Kovarik, J.,; Kunze, R.,; Küster, Thomas,; Laconi, R.,; Lang, A.,; Lang, H.R.M.,; Lechner, K.,; Leimbacher, W.,; Leimbacher, Walter,; Leonard, J. V.,; Levine, Robert A.,; Linkesch, W.,; Lockhart, Ronan John,; Loviselli, A.,; Lutz, H.,; Lutz, Hermann,; Lutz, Hernann,; Margreiter, R.,; Mayer, G.,; Merwin, M.,; Miyata, Yusuke,; Nakamura, Shiro,; Neuheiser, F.,; Nichol, Charles A.,; Niederwieser, A.,; Niederwieser, Alois,; Niederwieser, D.,; Noël, C.,; Okano, Y.,; Oura, T.,; Oura, Toshiaki,; Pfleiderer, Wolfgang,; Pheasant, A.E.,; Piechowiak, H.,; Pohanka, E.,; Porcher, H.,; Primus, J.P.,; Prior, Ch.,; Redweik, Udo,; Reibnegger, G.,; Reibnegger, Gilbert,; Rokos, H.,; Rokos, K.,; Rosenblatt, David,; Rotthauwe, H. W.,; Róhrer, H.,; Salzer, G.M.,; Sawada, Y.,; Sawada, Yoshitomo,; Schloz, H.,; Schmiedmeier, W.,; Schoedon, G.,; Schoedon, Gabriele,; Schwarz, M.,; Schwarzinger, I.,; Shintaku, Haruo,; Shintuku, H.,; Smith, Gary K.,; Smith, I.,; Soyka, Rainer,; Speck, B.,; Stiefel, Th.,; Stockhausen, H.,; Stockhausen, W.,; Switchenko, A.C.,; Takahashi, S.,; Tanaka, Mitsuru,; Tocco, M.,; Traub, Herman,; Traub, Hermann,; Troppmair, J.,; Troppmair, Jacob,; Troppmair, Jakob,; Tsuruhara, T.,; Tsuruhara, Tsuneo,; Viscontini, Max,; Viveros, O. Humberto,; Voelter, W.,; Volc-Platzer, B.,; Wachter, H.,; Wachter, Helmut,; Werner, E. R.,; Werner, E.R.,; Werner, Ernst R.,; Wildgrube, H.J.,; Woloszczuk, W.,; Woolf, Jeffrey H.,; Wächter, H.,; Wächter, Helmut,; Würsch, A.,; Yamato, Kazumi,; Zagalak, B.,; Zeitler, H.-J.,; Ziegler, I.,; Zimmerman, Thomas P.,; Zoephel, Gerd Peter,
• HerausgeberIn: Curtius, H. Ch.,; Pfleiderer, W.,; Wachter, Helmut,
• Place / Publishing House: Berlin ;, Boston : : De Gruyter, , [2019]; ©1985
• Publicatiejaar: 2019
• Editie: Reprint 2019
• Taal: English
• Reeks: Biochemical and Clinical Aspects of Pteridines. Cancer - Immunology - Metabolic Diseases ; Vol. 4
• Fysieke beschrijving: 1 online resource (686 p.) :; Num. figs., tabs

Table of Contents

Frontmatter -- PREFACE -- LIST OF PARTICIPANTS -- CONTENTS -- 1. CHEMISTRY AND ANALYSIS OF PTERIDINES -- ELECTROLYSIS OF PTERIDINES -- NITRITE OXIDATION OF TETRAHYDROPTERINS -- ACYLATION OF TETRAHYDROPTERINS -- SYNTHESIS AND PROPERTIES OF 5,6-DIHYDROPTERIDINES -- SYNTHESIS AND PROPERTIES OF NEW TETRAHYDROPTERIDINES -- INTER- AND INTRAMOLECULAR REDOX-REACTIONS BY 5,6- RESP. 7,8-DIHYDROPTERINES; DO THESE COMPOUNDS BEHAVE AS REDOX COFACTORS DURING THE BIOSYNTHESIS OF 5,6,7,8-TETRAHYDRO-L-BIOPTERIN ? -- DETERMINATION OF NEOPTERIN AND REDUCED NEOPTERINS BY RADIOIMMUNOASSAY -- THE DETERMINATION OF PTERINS, BIOGENIC AMINE METABOLITES, AND AROMATIC AMINO ACIDS IN CEREBROSPINAL FLUID USING ISOCRATIC REVERSE PHASE LIQUID CHROMATOGRAPHY WITH IN SERIES DUAL CELL COULOMETRIC ELECTROCHEMICAL AND FLUORESCENCE DETECTION:- USE IN THE STUDY OF INBORN ERRORS OF DIHYDROPTERIDINE REDUCTASE AND 5,lO-METHYLENETETRAHYDROFOLATE REDUCTASE -- 2. BIOCHEMISTRY AND METABOLISM OF PTERIDINES -- TETRAHYDROBIOPTERIN METABOLISM IN THE CENTRAL NERVOUS SYSTEM -- ENZYMATIC FORMATION OF H4-BIOPTERIN IN DROSOPHILA MELANOGASTER -- TETRAHYDROBIOPTERIN BIOSYNTHESIS. STUDIES ON THE REACTION OF DIHYDRONEOPTERIN TRIPHOSPHATE IN THE PRESENCE OF PHOSPHATE-ELIMINATING ENZYME FROM HUMAN LIVER -- BIOSYNTHESIS OF TETRAHYDROBIOPTERIN: INCORPORATION OF LABEL FROM REDUCED PYRIDINE NUCLEOTIDE DURING FORMATION FROM DIHYDRONEOPTERIN TRIPHOSPHATE -- TETRAHYDROBIOPTERIN BIOSYNTHESIS IN MAN -- PHOSPHORYLATION OF UNPROTECTED D-NEOPTERIN -- MEASUREMENT OF PHOSPHATE-ELIMINATING ENZYME (PEE) ACTIVITY IN LIVER BIOPSIES -- INHIBITION OF THE TETRAHYDROPTERIN PATHWAY FOR BIOPTERIN COFACTOR BIOSYNTHESIS BY N-ACETYLSEROTONIN IN CELL CULTURES AND IN ENZYME PREPARATIONS AND STUDIES ON THE MECHANISM OF TETRAHYDROPTERIN FORMATION -- ACTH STIMULATION OF TETRAHYDROBIOPTERIN BIOSYNTHESIS AND STEROIDOGENESIS IN ADRENAL CORTICAL TUMOR CELLS IN CULTURE -- ENDOCRINE AND METABOLIC REGULATION OF GTP-CYCLOHYDROLASE ACTIVITY AND TETRAHYDROBIOPTERIN LEVELS IN RAT LIVER -- TETRAHYDROBIOPTERIN SYNTHESIS AND THE ROLE OF THE COFACTOR IN THE REGULATION OF TYROSINE HYDROXYLATION IN ADRENOMEDULLARY CHROMAFFIN CELLS -- BIOPTERIN METABOLISM IN HEPATOMA CELLS -- HIGH BIOPTERIN CONCENTRATION IN NUCLEAR FRACTIONS OF REGIONAL RAT-BRAIN PREPARATIONS -- 3. TETRAHYDROBIOPTERIN DEFICIENCIES, DIAGNOSIS AND THERAPY -- TRANSIENT NEONATAL HYPERPHENYLALANINEMIA DUE TO DEFECTIVE SYNTHESIS OF 7,8-DIHYDROBIOPTERIN -- TETRAHYDROBIOPTERIN ANALOGUES AND THEIR ABILITY TO ENTER THE RAT STRIATUM AFTER PERIPHERAL ADMINISTRATION -- 4. PTERIDINES IN IMMUNOLOGY -- IMMUNE RESPONSE- ASSOCIATED NEOPTERIN RELEASE: AN OVERVIEW -- NEOPTERIN ESTIMATION an in vivo test measuring the cell mediated immune status -- NEOPTERIN IN SERUM OF MAMMALS? -- The Relations of HTLV-III antibodies to Neopterin and Beta-2- Microglobulin in the Serum of Patients with AIDS or Persons at Risk -- INCREASE IN SERUM NEOPTERIN LEVELS IN PATIENTS RECEIVING RECOMBINANT INTE RLE UK IN-2 AND RECOMBINANT INTERFERON CC A -- CLINICAL RESOLVEMENT OF MALARIA INFECTION PARALLELS DECREASE OF HIGHLY ELEVATED SERUM NEOPTERIN LEVEL -- ACCUMULATION AND RELEASE OF PTERIDINES DURING STIMULATION OF HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS: PARTICIPATION IN THE CONTROL OF ANTIGEN INDUCED T-CELL EXPANSION -- INTRACELLULAR CHANGES IN PTERIN RELEASING PERIPHERAL BLOOD MONONUCLEAR CELLS AFTER STIMULATION WITH INTERFERON-GAMMA -- METABOLISM OF PTERINS IN HUMAN PERIPHERAL BLOOD MONONUCLEAR -- URINARY NEOPTERIN EXCRETION IN THE FOLLOW UP OF BONE MARROW TRANSPLANT RECIPIENTS -- PTERIDINES IN BONE MARROW TRANSPLANTATION: THE PROBLEM OF PHARMACOLOGICAL. INTERACTIONS -- SERUM NEOPTERIN DETERMINATION IN BONE MARROW TRANSPLANTATION IN CHILDHOOD -- RADIOIMMUNOLOGICAL DETERMINATION OF SERUM NEOPTERIN IN PATIENTS FOLLOWING BONE MARROW TRANSPLANTATION - FIRST RESULTS -- PTERIDINES IN URINE AND SERUM IN KIDNEY ALLOGRAFT RECIPIENTS -- RELATION OF NEOPTERIN TO INTERFERON GAMMA SERUM LEVELS IN PATIENTS WITH KIDNEY TRANSPLANTS -- SERUM NEOPTERIN IN PATIENTS WITH KIDNEY ALLOGRAFTS: CLINICAL IMPLICATIONS -- URINARY NEOPTERIN IN ACUTE AND CHRONIC LIVER DISEASES -- URINARY NEOPTERIN EXCRETION AS AN ACTIVITY PARAMETER IN CROHN'S DISEASE -- INTERFERON-GAMMA-INDUCED IN VITRO-EXCRETION OF NEOPTERIN AND 3-HYDROXYANTHRANILIC ACID BY HUMAN MACROPHAGES -- 5. PTERIDINES IN CANCER AND OTHER DISEASES -- INTERPRETATION OF THE VARIABLE NEOPTERIN EXCRETION IN PATIENTS WITH DIFFERENT TUMOR TYPES - A HYPOTHESIS -- URINARY NEOPTERIN IN CHILDREN WITH MALIGNANT NEOPLASM -- THE CLINICAL RELEVANCE OF THE NEOPTERIN-DETERMINATION IN PATIENTS WITH CERVICAL AND OVARIAN CANCER -- DETERMINATION OF SERUM NEOPTERIN IN PATIENTS WITH ACUTE LEUKEMIA AND MALIGNANT LYMPHOMAS -- NEOPTERIN - A MARKER OF THE CELLULAR IMMUNE RESPONSE IN PATIENTS WITH LUNG CANCER -- Neopterin levels in different human tumors under treatment with antitumoral peptides (Factor AF2), course, response rate, prognosis -- PTERIDINES IN PLASMA AND IN BLOOD CELLS FROM LEUKAEMIA PATIENTS -- PTERIDINES FROM BONE MARROW AND BODY FLUIDS FROM HEALTHY DONORS AND FROM DIFFERENT PATIENTS -- PTERIDINE LEVELS IN PATIENTS WITH AIDS (ACQUIRED IMMUNODEFICIENCY SYNDROME) AND WITH KAPOSI'S SARCOMA -- Comparative Studies on Urinary Neopterin Excretion and other Laboratory Parameters -- 6. MISCELLANEOUS -- EFFECT OF PTERIDINES ON HYDROXY-INDOLE-O-METHYLTRANSFERASE HIOMT) -- PTERIDINE VALUES IN CEREBROSPINAL FLUID IN SICK CHILDREN -- EXOGENOUS FACTORS INFLUENCING THE EXCRCETION OF NEOPTERIN -- NEONATAL MEGALOBLASTIC ANEMIA CAUSED BY AN INHERITED DEFECT IN THE METHIONINE SYNTHETASE REACTION IN VIVO -- AUTHOR INDEX -- SUBJECT INDEX -- Backmatter