Lymphocyte Activation and Differentiation : : Fundamental and Clinical Aspects. Proceedings of the 18th International Leucocyte Culture Conference. La Grande Motte, France, June 19–24, 1987 / / ed. by J. Dornand, J. C. Mani.
Saved in:
| Other title: | Frontmatter -- PREFACE -- CONTENTS -- INTRODUCTION -- Fundamental and Clinical Aspects of Lymphocyte Activation and Differentiation -- PLENARY LECTURE -- Oncogenes and Multistep Carcinogenesis -- SYMPOSIA BIOCHEMICAL AND CELLULAR ASPECTS OF LYMPHOCYTE ACTIVATION -- Biochemical and Molecular Events Controlled by Lymphoid and Myeloid Growth Factors -- PGE2 Inhibition of Human T Lymphocytes Proliferation: Regulatory Effect of PGE2 on the Intra-Cellular Signaling Pathways -- Structure-Function Relationships for the Interleukin 2 Receptor -- Monovalent Cation Fluxes as Regulators of Critical Nuclear Events in Lymphocyte Activation: Mirror Image Processes in Differentiation and Proliferation -- Diacylglycerol, Calcium, cAMP and cGMP Mediate Qualitatively Distinct Protein Kinase C Translocation Events in Normal B Lymphocytes -- Phosphorylation of Prosolin and Leucocyte Growth Regulation -- DIFFERENTIATION OF T AND B LYMPHOCYTES -- Regulation of Human B Cell Function -- The Role of Lymphokines in the Immunoglobulin Class Switch -- Mouse and Human B Cell Activating Factors -- Molecular Cloning of the Murine T11 (CD2) cDNA -- Antigen Expression and Proliferative Activity during B and T Cell Development -- MOLECULAR BIOLOGY OF LEUCOCYTES (ANTIGENS, RECEPTORS, INTERLEUKINS) -- The Molecular Biology of the Multisubunit Interleukin-2 Receptor -- Expression and Rearrangement of T Cell Receptor Genes in Human Leukemic T Cell Lines -- The Human T-Cell Rearranging γ Genes (TRGγ) -- Immunoglobulin Gene Expression -- Structure and Expression of Mouse Fcy Receptor II (FcyRII) -- VIRUS-INDUCED LYMPHOCYTE DYSFUNCTIONS -- The Impact of the Presence of EBV on the Interaction of B Cell Lines with T Lymphocytes -- Induction of B Cell Activation Markers by Epstein-Barr Virus -- Production of Interleukin-1 (IL1) by EBV-Infected Cells -- DNA-Mediated Gene Transfer of Epstein-Barr Virus Receptor onto Murine Fibroblasts -- ACCESSORY CELL FUNCTIONS -- Modulation of IL1 Receptor Expression by IL1, Prostaglandins and Glucocorticoids -- Tumor Necrosis Factors: Modulation of Synthesis and Biological Activities -- Analysis of the Structure and Function of Immunectin -- Natural Effector Cells of the Intestinal Epithelium: Ontogeny, Function, and Regulation -- Analysis of Ia-Transfected Fibroblasts: Antibody and T Cell Recognition Sites Segregate with the 31 Domain of the E3 Polypeptide Chain -- WORKSHOPS WORKSHOP A. GROWTH AND DIFFERENTIATION FACTORS -- Inhibition by Cyclosporin A of the IL2 Dependent Autocrine Growth in a Human Tumor T Cell Line and Fate of IL2 Receptors after Endocytosis -- Interleukin B, a B Cell-Derived Lymphokine -- Induction and Enhancement of Lymphokine Gene Expression in Human T Cell Clones Transfected with HTLV-I pX cDNA -- Evidence for a Human B Cell Activating Factor Acting on Resting B Lymphocytes -- Splicing Intermediates of the IL-2 Receptor (p55 Subunit) -- The Role of Plasminogen Activator in Regulating T Cell Proliferation and Interferon Production -- Membrane and Soluble IL2-R Produced by Human T Cell Clones: A Comparative Study -- Phenotype and Cytokines Production by Human Myeloma Cell Lines -- B + Null Cell-Derived Prothymocyte Differentiating Activity (PTDA): Biological Properties and Physicochemical Characterization -- TDM-Activated Macrophages Produce a Cytostatic Factor Distinct from TNFα, IFNα,β, and IL-1 -- Characterization of a Factor Produced by Human Alloreactive T Cell Clones -- WORKSHOP B. MECHANISMS OF AUTOIMMUNITY -- Effector Mechanisms of Autoimmune Diseases -- T Cell Response to Myelin Basic Protein in Healthy Subjects and Multiple Sclerosis Patients -- Active T Cell Regulation of Autoimmune Responses in Autoimmune and "Nonautoimmune" Spleen Cell Populations -- Interleukin-2 Receptor Targeted Immunotherapy of Autoimmune Diseases: Treatment Strategies for Type I Diabetes -- Protection of Non-Obese Diabetic (NOD) Mice from Insulitis by Neonatal Injection of F1 Spleen Cells -- WORKSHOP C. ONCOGENES AND LEUCOCYTE TRANSFORMATION -- Complex Transcriptional Regulation of Nuclear Proto Oncogenes: Existence of a Block to Elongation in C-Myc and C-Fos Genes -- Determinants of C-Fos and C-Myc mRNAs Instability -- Cloning and Functional Analysis of the Human C-fms Gene -- Effects of Proliferative (Interleukin, Colony Stimulating Factors) and Antiproliferative (Cyclic AMP, Interferon) Signals on Gene Expression in Myeloid and Lymphoid Cell Lines -- The Progession to Tumourigenes is Following Transformation of Murine Myelomonocytic Cell by V-Myc -- HTLV-I Infection of a Human Antigen Specific Proliferating/Cytotoxic T Cell Clone Results in a Loss of Cytotoxicity but does not Affect the T Cell Receptor -- WORKSHOP D. EXPERIMENTAL MODELS OF IMMUNOMODULATION -- Roles of Monokines in the Nonspecific Host Defence Stimulated by Exogenous Agents -- Enhancement of the Immune Response Using a Synthetic B-Lymphocyte Mitogen Covalently Linked to Antigens -- Effects of in vivo Treatment of Mice with Anti-Murine T3 Antibody: Suppression of Transplantation Responses -- Gamma-Interferon Protects Listeria-Susceptible BALB/c Mice from Lethal Listeriosis without Affecting the Development of Protective Immunity -- Effect of a Lipophilic Muramylitri peptide on Gamma-Interferon Induced Major Histocompatibility Antigen (MHC) and Leu-M3 Antigen Changes in Human Monocytes -- Effect of Cyclosporin A (CsA) on the Induction of Memory T Lymphocytes -- Modulation by Cyclosporin A (CsA) of the Immune System of Mice Infected with Lymphocytic Choriomeningitis Virus (LCMV) -- Modulation of Lymphocyte Activation in vitro by a Soluble Placental Factor -- The Role of Interleukins and the Interleukin-2 Receptor in the Pathogenesis of Murine Cutaneous Leishmaniasis -- In vitro Studies of Synthetic Glycolipids: A New Class of Compounds with Immunomodulating Activity -- Immunotoxicity Studies of PCB (Aroclor 1254) in the Adult Rhesus (Macaca mulatta) Monkey -- Human Cytomegalovirus Induces Alterations in Mixed Lymphocyte Reactions -- WORKSHOP E. IMMUNODEFICIENCIES -- Immunological Aspects of AIDS and HIV Infection -- Studies Regarding the Interaction of the T4 (CD4) Molecule with the Envelope Protein gp120 of the Human Immunodeficiency Virus (HIV) -- Low Level Re-Expression of the Silent MHC Class-II Genes in the Lymphoblasts from Patients with the HLA-Class II Deficient SCID -- Adenylate Cyclase and 5'Nucleotidase Activities of Peripheral Blood Mononuclear Cells is Psoriasis -- WORKSHOP F. NATURAL KILLER CELLS -- Natural Killer Cells -- Characterization and Population Kinetics of Liver-Associàted Large Granular Lymphocytes (Natural Killer Cells) -- Modulation of Lymphonkine Activated Killer Activity of Lymphocytes Isolated from Human Peripheral Blood and Bone Marrow by Recombinant IL4 -- Inhibition of Human Natural Killer Cells by Resistant Target Cells -- Changes in Gene Expression Associated with Activation or Inhibition of Natural Killer Function -- Fibronectin Expression by Endogenous and Activated NK Cells -- Cytolytic Potential of CD3+4-8- T Cells with Differently Organized T Cell Receptor Y Chains -- WORKSHOP G, DIFFERENTIATION AND ACTIVATION OF T LYMPHOCYTES -- CD1a Molecules Form Intermolecular Complexes with HLA Class I Molecules or Other CD1 Molecules on Normal Human Thymus Cells -- The CD2 Pathway of Activation. Epitope Requirements, Linkage to Other Surface Molecules and Early Biochemical Events -- A T-Cell Surface Molecule Different from CD2 is Involved in Spontaneous Rosette Formation with Erythrocytes -- A Dual Function of the T4 Molecule in the Cytolytic Activity of Human T Cell Clones -- Role of Antigen-Specific T Cell Receptor and Associated Proteins in the Activation of a Cytolytic T Cell Clone Analysed by Protein Phosphorylation and by T Cell Receptor Negative Variants -- Y-Chain T Cell Receptors on Denoritic Epidermal Cells -- Stimulation of T Cells via LY-6C: A Phssphatidylinositol-Anchored Cell Surface Molecule which Generates Intracellular Calcium Mobilization upon Cross-Linking -- New Subgroups in the Human T Cell Rearranging VΓ Gene Locus -- Genomic Organisation of the Constant Regions of the Human T-Cell Rearranging Gene Γ -- Second Signals for T Cell Mitogenesis Provided by a MAbs CD45 (T200) and CD5 (T1) -- WORKSHOP H. DIFFERENTIATION AND ACTIVATION OF B LYMPHOCYTES -- Immunobiology of B Lymphocytes -- Regulation of B Lymphocyte Responsiveness by Multiple Cytokines -- Influence of IL4 on the Induction of Immunoglobulin Secretion by BCAF-Containing Supernatant -- Early B Cells Immortalized by Epstein-Barr Virus (EBV) - A Phenotypic Study -- The Human B Cell Repertoire: Multispecificity as a Major Characteristic of Antibodies Secreted by Human EBV-Transformable Cord Blood B Cells -- Analysis of Excessive B Cell Growth in Lymph Nodes of L. major Infected Mice: The Effect of L. major Specific T-Cell Clones -- Antibody Response in vitro of Human Peripheral Blood Lymphocytes: Application of a Limiting Dilution Method -- Frequency Analysis of Functional Immunoglobulin CE Gene Expression in LPS-Reactive Murine B Cells -- Changes in Gene Expression in Differentiating B Lymphocytes -- Regulation of Lipopolysaccharide (LPS)-Induced B Cell Differentiation by Ly-5 and Uyb-2 Molecules -- WORKSHOP I. LIPIDIC MEDIATORS OF THE IMMUNE RESPONSE -- Phospholipid-Derived Mediators and the Immune Response -- Anti-Oxidants and IL2 Synthesis -- Role of Lipoxygenase Pathway Products in IL2 Synthesis -- Platelet Activating Factor (PAF) Induces Human Suppressor Cell Activity -- PAF-Acether Induces an Enhanced Release of Interleukin-1 (IL-1) from Human Monocytes -- Down-Regulation of CD2 and CD3 Antigen Expression by PAF-Acether -- WORKSHOP J. NEURAL MODULATION OF IMMUNITY -- Neuroendocrine Modulation of Immunity -- Cyclic AMP Response to Dopamine in the Human Monocyte-Like Cell Line U-937 -- ß-Endorphin Inhibits Thy-1 Antigen Expression on Murine Thymocytes and Antagonizes Thymosin Fraction V Action -- WORKSHOP K. BIOCHEMISTRY OF LEUCOCYTE STIMULATION AND EFFECTOR MECHANISMS -- Genes Preferentially Expressed in Cytolytic T Cells -- Signal Transduction in Lymphocyte Activation -- IL-2 Mediated Induction of Lytic Granules, Perforin, and BLT-Esterase in Potent, Granule-Free Cytolytic T Lymphocytes Indicates an Alternative Function of Lytic Granules -- Extracel1ular ATP Initiates the Proliferative Response of PMA-Activated Medullary Thymocytes by Increasing their Cytosolic Free Calcium Concentration -- Evidence for a Kinase Cascade Stimulated by Interleukin 2 in Cytotoxic T Cell Clones -- The Regulation of Cytoskeletal Protein Gene Expression in Lymphocytes -- Protein Phosphorylation During T Cell Activation -- Clues to Mechanisms of Activation for Killing from the Observations of Changes in Intracellular (Ca++) in Individual Cytolytic T Cells and Targets -- Induction of Activation Signals in Human T Lymphocytes -- Both Lyt2+ and L3T4+ Cell Subsets Secrete the Serine Esterase Granzyme A in Response to a Specific Antigenic Stimulus -- WORKSHOP L. ACCESSORY CELLS-LYMPHOCYTE INTERACTIONS -- Accessory Cells-Lymphocyte Interactions -- A Role for HLA-Class I Molecules from Accessory Cells in T-Cell Activation -- Adhesion Molecules of Monocytes -- Cellular and Molecular Basis of Self-Induced Proliferation of T Lymphocytes (SIPofT) -- Human T Cell Activation: Participation of T Cell Differentiation Antigen Cluster 2 (CD2) in the Generation and/or Transduction of Accessory Cell Signals -- WORKSHOP PI. IDIOTYPIC REGULATION -- The Influence of Vk Gene Polymorphism on the Induction of Silent Idiotypes in the Arsonate System -- Allogeneic Manipulation of the "GAT" Idiotypic Cascade does not Influence the VH Gene Usage -- Specific Suppression of the Primary Antibody Response with Immune Complexes Formed in Antibody Excess Depends on the Idiotype and the Isotype of the Antibody Forming the Complex -- The HLA-Restricted Presentation of Idiotype to Human Anti-Idiotypic T Cell Clones does not Require Processing by Antigen Presenting Cells -- Idiotypic Predominance Alteration in Anti-Arsonate Response by Priming with Anti-Idiotypic Antibodies -- Anti-Idiotype Induction of Humoral Immunity in Cattle -- Anti MHC-Receptor Cytotoxic T Lymphocytes: Their Role in the Specific Resistance to Graft-Versus-Host Reaction -- Altered Anti-Idiotype Response to a(1-3)Dextran-Associated Idiotypes in Mice Bearing an X-Linked Immune Defect -- WORKSHOP N. COMPLEMENT RECEPTORS -- Human CD3 Complement Receptors -- Influence of Antigen-Bound Complement Components C3b and C4b in Activation of Human T-Cell Clones -- Human C3 and C3dg Stimulate Proliferation of a Pre-B Lymphoblastoid Cell Line via CR2 Complement Receptor -- Activation of B Lymphocytes by Zymosan-Bound C3 Fragments -- Contribution of C3 Fragments to Lymphocyte Mediated Lysis of CR2 Carrying Cells -- "In vivo" and "in vitro" Modulation of CR1 (C3b Receptor) Expression by its Ligand C3b -- WORKSHOP O. MAJOR HISTOCOMPATIBILITY COMPLEX -- MHC in Leucocyte Biology -- HLA Class I α1, α2, and ß2-Microglobulin Domain Interactions -- Diversity and Function of Human Class II MHC Antigens -- DRα-DQß Mismatched Isotype Pairing Occurs in EBV Transformed B Cell Lines -- Distinct Epitopes for Kd-Restricted Cytolytic T Cells Specific for HLA-CW3 or HLA-A24 Map to the same Region of HLA -- Resistance or Susceptibility of Human Target Cells to NK Lysis: Correlation with the Surface Expression of HLA Class I Molecules and Induction of Susceptibility by Monoclonal Anti Class I Antibodies -- WORKSHOP P (SANOFI). CLINICAL APPLICATIONS OF ANTILEUCOCYTE MONOCLONAL ANTIBODIES -- Anti-Leucocyte Monoclonal Antibodies: From Laboratory Reagents to Therapeutic Agents -- Treatment of Donor Bone Marrow with FabT101 Ricin A-Chain Immunotoxin for the Prevention of Graft-versus-Host Disease after Allogeneic Bone Marrow Transplantation -- Monoclonal Antibodies for Bone Marrow Purging before Transplantation: A Brief Review -- Comparative Efficiency of an Immunomagnetic Purging Procedure and a Rabbit Complement Lysis to Eliminate BL Cells from the Bone Marrow -- In vivo Antigenic Modulation of CD5+ Cells in Renal Transplanted Patients Receiving Anti-CD5 Antibody Infusions -- In vivo Therapy by CD8 Monoclonal Antibody for Delays to Hematological Recovery after Autologous Bone Marrow Transplantation -- Autologous Bone Marrow Transplantation for Acute Lymphoblastic Leukemia in Remission. In vitro Purging of Inoculum with Monoclonal Antibodies and Complement -- Immunosuppression by Murine Monoclonal Antibodies: The Rhesus Monkey Used for Preclinical Testing -- Therapeutic Applications of Monoclonal Antibodies for Lymphoma and Leukemia -- BMA 031 - The TCR Specific Monoclonal Antibody for Clinical Applications -- Immunoassays for the Monitoring of Kidney Graft's Transplanted Patients under 33B3.1 MOAB Therapy -- Prospective Randomized Studies of T Cell Depletion in HLA Matched Bone Marrow Transplantation (BMT) for Leukemia: 2 Studies of the GEGMO in 92 Patients -- A Monoclonal Anti Interleukin 2 Receptor Prevents Human Kidney Graft Rejection -- Clinical Pharmacology of 0KT3 -- Introduction to the Clinical Use of Monoclonal Antibodies as Immunosuppressive Agents -- General Considerations on the Quality Control of Monoclonal Antibodies before Therapeutic Use in Man -- Immunotoxins with Therapeutic Use in Man -- AUTHOR INDEX -- SUBJECT INDEX -- Backmatter |
|---|---|
| Format: | Mode of access: Internet via World Wide Web. |
| ISBN: | 9783110850253 9783110637243 |
| DOI: | 10.1515/9783110850253 |
| Access: | restricted access |
| Hierarchical level: | Monograph |
| Statement of Responsibility: | ed. by J. Dornand, J. C. Mani. |
Similar Items
-
B lymphocyte adhesion and activation / by Pia Björck
by: Björck, Pia
Published: (1994) -
The leucocyte antigen factsbook / A. Neil Barclay ... [et al.].
Published: (c1997.) -
The polymorphic CD3 differentiation antigen of rhesus monkey lymphocytes / door Franciscus Joannes Maria Nooij
by: Nooij, Franciscus Joannes Maria
Published: (1988) -
Differentiation and Mechanisms of Activation of Innate Lymphoid Cells
by: Cella, Marina
Published: (2019) -
Lucretia Mott / / Otelia Cromwell.
by: Cromwell, Otelia,
Published: ([2013])