Study of intracellular signaling pathways in Chronic Myeloproliferative Neoplasms / / Serena Martinelli.
A gain-of-function mutation in Janus kinase 2 (JAK2V617F) is at the basis of the majority of chronic myeloproliferative neoplasms (MPN). Enhanced activation of other downstream pathways including the PI3K/mTOR pathway has been documented as well. In this study we evaluated the effects of JAK1/2 inhi...
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| Superior document: | Premio Tesi di Dottorato |
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| VerfasserIn: | |
| Place / Publishing House: | Florence : : Firenze University Press,, 2017. |
| Publicatiejaar: | 2017 |
| Taal: | English |
| Reeks: | Premio tesi di dottorato.
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| Fysieke beschrijving: | 1 online resource (80 pages). |
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