More and more people in our affluent society are affected by metabolic disorders. Metabolic processes not only play a central role in the development of classic metabolic disorders such as diabetes, but are also causally involved in the development of other widespread diseases including infectious diseases, cancer, cardiovascular diseases and diseases of the immune system.
With a strictly interdisciplinary research approach, the Cori Institute of Molecular and Computational Metabolism in Graz aims to gain new insights into metabolic processes. Cellular metabolic processes are systematically, experimentally and molecularly examined and modeled with the help of mathematical methods. Specialists from different disciplines such as medicine, mathematics, computer science, biology, chemistry and engineering will work closely together in the research groups. These new approaches offer hope for the diagnosis and treatment of related diseases.
Cori Institute: Specific Goals
The Cori Institute of Molecular and Computational Metabolism in Graz pursues the following specific goals in combining excellent experimental metabolic research with mathematical modeling and simulation:
- Discovery of new metabolic processes in the development and course of environmental and age-related metabolic diseases.
- Clarification of the role of the metabolism of pathogenic microorganisms and their host cells in the pathogenesis of infectious diseases.
- Investigation of the role of metabolism in the development of cancer and cancer-associated cachexia.