Topics on Drug Metabolism / / edited by James Paxton.
In order to avoid late-stage drug failure due to factors such as undesirable metabolic instability, toxic metabolites, drug-drug interactions, and polymorphic metabolism, an enormous amount of effort has been expended by both the pharmaceutical industry and academia towards developing more powerful...
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| Place / Publishing House: | Croatia : : IntechOpen,, 2012. |
| Year of Publication: | 2012 |
| Language: | English |
| Physical Description: | 1 online resource (308 pages) |
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(CKB)3230000000077134 (NjHacI)993230000000077134 (oapen)https://directory.doabooks.org/handle/20.500.12854/61004 (EXLCZ)993230000000077134 |
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James Paxton auth Topics on Drug Metabolism / edited by James Paxton. IntechOpen 2012 Croatia : IntechOpen, 2012. 1 online resource (308 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier Description based on publisher supplied metadata and other sources. In order to avoid late-stage drug failure due to factors such as undesirable metabolic instability, toxic metabolites, drug-drug interactions, and polymorphic metabolism, an enormous amount of effort has been expended by both the pharmaceutical industry and academia towards developing more powerful techniques and screening assays to identify the metabolic profiles and enzymes involved in drug metabolism. This book presents some in-depth reviews of selected topics in drug metabolism. Among the key topics covered are: the interplay between drug transport and metabolism in oral bioavailability; the influence of genetic and epigenetic factors on drug metabolism; impact of disease on transport and metabolism; and the use of novel microdosing techniques and novel LC/MS and genomic technologies to predict the metabolic parameters and profiles of potential new drug candidates. English Drugs. Toxicology and Pharmaceutical Science Pharmacology Pharmacokinetics Health Sciences 953-51-0099-8 Paxton, James, editor. |
| language |
English |
| format |
eBook |
| author |
James Paxton |
| spellingShingle |
James Paxton Topics on Drug Metabolism / |
| author_facet |
James Paxton Paxton, James, |
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j p jp |
| author2 |
Paxton, James, |
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j p jp |
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TeilnehmendeR |
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James Paxton |
| title |
Topics on Drug Metabolism / |
| title_full |
Topics on Drug Metabolism / edited by James Paxton. |
| title_fullStr |
Topics on Drug Metabolism / edited by James Paxton. |
| title_full_unstemmed |
Topics on Drug Metabolism / edited by James Paxton. |
| title_auth |
Topics on Drug Metabolism / |
| title_new |
Topics on Drug Metabolism / |
| title_sort |
topics on drug metabolism / |
| publisher |
IntechOpen IntechOpen, |
| publishDate |
2012 |
| physical |
1 online resource (308 pages) |
| isbn |
953-51-4354-9 953-51-0099-8 |
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R - Medicine |
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RM - Therapeutics and Pharmacology |
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RM300 |
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RM 3300 T675 42012 |
| illustrated |
Not Illustrated |
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600 - Technology |
| dewey-tens |
610 - Medicine & health |
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615 - Pharmacology & therapeutics |
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615.1 |
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3615.1 |
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615.1 |
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615.1 |
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AT jamespaxton topicsondrugmetabolism AT paxtonjames topicsondrugmetabolism |
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(CKB)3230000000077134 (NjHacI)993230000000077134 (oapen)https://directory.doabooks.org/handle/20.500.12854/61004 (EXLCZ)993230000000077134 |
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Topics on Drug Metabolism / |
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