Topics on Drug Metabolism / / edited by James Paxton.
In order to avoid late-stage drug failure due to factors such as undesirable metabolic instability, toxic metabolites, drug-drug interactions, and polymorphic metabolism, an enormous amount of effort has been expended by both the pharmaceutical industry and academia towards developing more powerful...
Saved in:
| : | |
|---|---|
| TeilnehmendeR: | |
| Place / Publishing House: | Croatia : : IntechOpen,, 2012. |
| Year of Publication: | 2012 |
| Language: | English |
| Physical Description: | 1 online resource (308 pages) |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| LEADER | 00847nam a2200277 i 4500 | ||
|---|---|---|---|
| 001 | 993547808404498 | ||
| 005 | 20221010153316.0 | ||
| 006 | m o d | ||
| 007 | cr ||||||||||| | ||
| 008 | 221010s2012 ci o 000 0 eng d | ||
| 020 | |a 953-51-4354-9 | ||
| 035 | |a (CKB)3230000000077134 | ||
| 035 | |a (NjHacI)993230000000077134 | ||
| 035 | |a (oapen)https://directory.doabooks.org/handle/20.500.12854/61004 | ||
| 035 | |a (EXLCZ)993230000000077134 | ||
| 040 | |a NjHacI |b eng |e rda |c NjHacl | ||
| 041 | 0 | |a eng | |
| 050 | 4 | |a RM300 |b .T675 2012 | |
| 082 | 0 | 4 | |a 615.1 |2 23 |
| 100 | 1 | |a James Paxton |4 auth | |
| 245 | 0 | 0 | |a Topics on Drug Metabolism / |c edited by James Paxton. |
| 260 | |b IntechOpen |c 2012 | ||
| 264 | 1 | |a Croatia : |b IntechOpen, |c 2012. | |
| 300 | |a 1 online resource (308 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 588 | |a Description based on publisher supplied metadata and other sources. | ||
| 520 | |a In order to avoid late-stage drug failure due to factors such as undesirable metabolic instability, toxic metabolites, drug-drug interactions, and polymorphic metabolism, an enormous amount of effort has been expended by both the pharmaceutical industry and academia towards developing more powerful techniques and screening assays to identify the metabolic profiles and enzymes involved in drug metabolism. This book presents some in-depth reviews of selected topics in drug metabolism. Among the key topics covered are: the interplay between drug transport and metabolism in oral bioavailability; the influence of genetic and epigenetic factors on drug metabolism; impact of disease on transport and metabolism; and the use of novel microdosing techniques and novel LC/MS and genomic technologies to predict the metabolic parameters and profiles of potential new drug candidates. | ||
| 546 | |a English | ||
| 650 | 0 | |a Drugs. | |
| 653 | |a Toxicology and Pharmaceutical Science | ||
| 653 | |a Pharmacology | ||
| 653 | |a Pharmacokinetics | ||
| 653 | |a Health Sciences | ||
| 776 | |z 953-51-0099-8 | ||
| 700 | 1 | |a Paxton, James, |e editor. | |
| 906 | |a BOOK | ||
| ADM | |b 2023-02-22 19:49:08 Europe/Vienna |f system |c marc21 |a 2012-12-09 08:17:33 Europe/Vienna |g false | ||
| AVE | |i DOAB Directory of Open Access Books |P DOAB Directory of Open Access Books |x https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5351640330004498&Force_direct=true |Z 5351640330004498 |b Available |8 5351640330004498 | ||