Synthetic biology is one of the latest fields of modern life sciences. Its aim is to use genetic building blocks to engineer and programme (micro-)organisms. Alongside new applications, however, there are also risks and ethical questions. SYNBIOSAFE was one of the first projects in the EU on the ethical and safety aspects of synthetic biology.
Synthetic biology promises to provide useful applications in many fields of science and technology, such as in the production of specific pharmaceuticals or the generation of energy. It was clear from a very early stage that such technology has the potential to revolutionise not only biology.
However, there are also possible risks that might result from deliberate misuse or from accidents. As a result, it is even more important to develop bio-safety strategies. At European level, SYNBIOSAFE was one of the first EU projects on synthetic biology that focused on ethical and safety aspects and attempted to contribute to the development of socially acceptable solutions.
Course of action
The project initially comprised a documentation of the state of research and the then current discussion on risks and ethics, presented as part of the first conference on synthetic biology in Europe in June 2007 in Zurich. An open electronic forum and an international workshop were intended to further stimulate the debate in Europe.
In conjunction with an investigation of bio-safety awareness amongst European researchers, this provided the basis for a highly regarded list of priority topics. The list was drawn up in collaboration with leading scientists in the fields of synthetic biology and secondary research and was published in a specialist journal.
The development of an awareness of the potential for risks and the search for methods to assess risks must begin at an early stage in the training of young scientists
When many individual scientists work on the production of synthetic components, there is a need for quality standards that can also be checked
Ethical problems result not only from the fact that life can be created synthetically , but also if for instance access to new technical opportunities is seriously restricted by means of patents and licenses
The many still unanswered questions mean that communication on the topic of synthetic biology is limited. Unlike in the case of genetic engineering, NGOs have not started any large-scale public debate.