List of Publications

YearTitleJournalAuthors
2022GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway.ElifeKroef, V., Ruegenberg, S., Horn, M., Allmeroth, K., Ebert, L., Bozkus, S., Miethe, S., Elling, U., Schermer, B., Baumann, U., Denzel, MS.
2022Redirecting Imipramine against Bluetongue Virus Infection: Insights from a Genome-wide Haploid Screening Study.PathogensJohn, L., Vernersson, C., Kwon, H., Elling, U., Penninger, JM., Mirazimi, A.
2022Transient upregulation of IRF1 during exit from naive pluripotency confers viral protection.EMBO RepRomeike, M., Spach, S., Huber, M., Feng, S., Vainorius, G., Elling, U., Versteeg, GA., Buecker, C.
2022DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions.Nat GenetButz, S., Schmolka, N., Karemaker, ID., Villaseñor, R., Schwarz, I., Domcke, S., Uijttewaal, ECH., Jude, J., Lienert, F., Krebs, AR., de Wagenaar, NP., Bao, X., Zuber, J., Elling, U., Schübeler, D., Baubec, T.
2022The HUSH complex controls brain architecture and protocadherin fidelity.Sci AdvHagelkruys, A., Horrer, M., Taubenschmid-Stowers, J., Kavirayani, A., Novatchkova, M., Orthofer, M., Pai, TP., Cikes, D., Zhuk, S., Balmaña, M., Esk, C., Koglgruber, R., Moeseneder, P., Lazovic, J., Zopf, LM., Cronin, SJF., Elling, U., Knoblich, JA., Penninger, JM.
2021The BTB-domain transcription factor ZBTB2 recruits chromatin remodelers and a histone chaperone during the exit from pluripotency.J Biol ChemOlivieri, D., Paramanathan, S., Bardet, AF., Hess, D., Smallwood, SA., Elling, U., Betschinger, J.
2021Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq.Nat CommunYelagandula, R., Bykov, A., Vogt, A., Heinen, R., Özkan, E., Strobl, MM., Baar, JC., Uzunova, K., Hajdusits, B., Kordic, D., Suljic, E., Kurtovic-Kozaric, A., Izetbegovic, S., Schaeffer, J., Hufnagl, P., Zoufaly, A., Seitz, T., Födinger, M., Allerberger, F., Stark, A., Cochella, L., Elling, U.
2020Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles.Nat MethodsMichlits, G., Jude, J., Hinterndorfer, M., de Almeida, M., Vainorius, G., Hubmann, M., Neumann, T., Schleiffer, A., Burkard, TR., Fellner, M., Gijsbertsen, M., Traunbauer, A., Zuber, J., Elling, U.
2020A human tissue screen identifies a regulator of ER secretion as a brain-size determinant.ScienceEsk, C., Lindenhofer, D., Haendeler, S., Wester, RA., Pflug, F., Schroeder, B., Bagley, JA., Elling, U., Zuber, J., von Haeseler, A., Knoblich, JA.
2019Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing.Nat CommunMoussa, HF., Bsteh, D., Yelagandula, R., Pribitzer, C., Stecher, K., Bartalska, K., Michetti, L., Wang, J., Zepeda-Martinez, JA., Elling, U., Stuckey, JI., James, LI., Frye, SV., Bell, O.
2019The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders.ElifeAng, CE., Ma, Q., Wapinski, OL., Fan, S., Flynn, RA., Lee, QY., Coe, B., Onoguchi, M., Olmos, VH., Do, BT., Dukes-Rimsky, L., Xu, J., Tanabe, K., Wang, L., Elling, U., Penninger, JM., Zhao, Y., Qu, K., Eichler, EE., Srivastava, A., Wernig, M., Chang, HY.
2019Derivation and maintenance of mouse haploid embryonic stem cells.Nat ProtocElling, U., Woods, M., Forment, JV., Fu, B., Yang, F., Ng, BL., Vicente, JR., Adams, DJ., Doe, B., Jackson, SP., Penninger, JM., Balmus, G.
2019CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci.Nat CommunChylinski, K., Hubmann, M., Hanna, RE., Yanchus, C., Michlits, G., Uijttewaal, ECH., Doench, J., Schramek, D., Elling, U.
2019Using Functional Genetics in Haploid Cells for Drug Target Identification.Methods Mol BiolVolz, JC., Schuller, N., Elling, U.
2018Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum GenetStephen, J., Nampoothiri, S., Banerjee, A., Tolman, NJ., Penninger, JM., Elling, U., Agu, CA., Burke, JD., Devadathan, K., Kannan, R., Huang, Y., Steinbach, PJ., Martinis, SA., Gahl, WA., Malicdan, MCV.
2018Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells.OncotargetHorn, M., Kroef, V., Allmeroth, K., Schuller, N., Miethe, S., Peifer, M., Penninger, JM., Elling, U., Denzel, MS.
2018Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency.Cell Stem CellMor, N., Rais, Y., Sheban, D., Peles, S., Aguilera-Castrejon, A., Zviran, A., Elinger, D., Viukov, S., Geula, S., Krupalnik, V., Zerbib, M., Chomsky, E., Lasman, L., Shani, T., Bayerl, J., Gafni, O., Hanna, S., Buenrostro, JD., Hagai, T., Masika, H., Vainorius, G., Bergman, Y., Greenleaf, WJ., Esteban, MA., Elling, U., Levin, Y., Massarwa, R., Merbl, Y., Novershtern, N., Hanna, JH.
2017DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells.Cell Stem CellChoi, J., Clement, K., Huebner, AJ., Webster, J., Rose, CM., Brumbaugh, J., Walsh, RM., Lee, S., Savol, A., Etchegaray, JP., Gu, H., Boyle, P., Elling, U., Mostoslavsky, R., Sadreyev, R., Park, PJ., Gygi, SP., Meissner, A., Hochedlinger, K.
2017CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.Nat MethodsMichlits, G., Hubmann, M., Wu, SH., Vainorius, G., Budusan, E., Zhuk, S., Burkard, TR., Novatchkova, M., Aichinger, M., Lu, Y., Reece-Hoyes, J., Nitsch, R., Schramek, D., Hoepfner, D., Elling, U.
2017Comparative glycoproteomics of stem cells identifies new players in ricin toxicity.NatureStadlmann, J., Taubenschmid, J., Wenzel, D., Gattinger, A., Dürnberger, G., Dusberger, F., Elling, U., Mach, L., Mechtler, K., Penninger, JM.