List of Publications

YearTitleJournalAuthors
2021Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq.Nat CommunYelagandula, R., Bykov, A., Vogt, A., Heinen, R., Özkan, E., Strobl, MM., Baar, JC., Uzunova, K., Hajdusits, B., Kordic, D., Suljic, E., Kurtovic-Kozaric, A., Izetbegovic, S., Schaeffer, J., Hufnagl, P., Zoufaly, A., Seitz, T., Födinger, M., Allerberger, F., Stark, A., Cochella, L., Elling, U.
2021The BTB-domain transcription factor ZBTB2 recruits chromatin remodelers and a histone chaperone during the exit from pluripotency.J Biol ChemOlivieri, D., Paramanathan, S., Bardet, AF., Hess, D., Smallwood, SA., Elling, U., Betschinger, J.
2020A human tissue screen identifies a regulator of ER secretion as a brain-size determinant.ScienceEsk, C., Lindenhofer, D., Haendeler, S., Wester, RA., Pflug, F., Schroeder, B., Bagley, JA., Elling, U., Zuber, J., von Haeseler, A., Knoblich, JA.
2020Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles.Nat MethodsMichlits, G., Jude, J., Hinterndorfer, M., de Almeida, M., Vainorius, G., Hubmann, M., Neumann, T., Schleiffer, A., Burkard, TR., Fellner, M., Gijsbertsen, M., Traunbauer, A., Zuber, J., Elling, U.
2019Using Functional Genetics in Haploid Cells for Drug Target Identification.Methods Mol BiolVolz, JC., Schuller, N., Elling, U.
2019Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing.Nat CommunMoussa, HF., Bsteh, D., Yelagandula, R., Pribitzer, C., Stecher, K., Bartalska, K., Michetti, L., Wang, J., Zepeda-Martinez, JA., Elling, U., Stuckey, JI., James, LI., Frye, SV., Bell, O.
2019Derivation and maintenance of mouse haploid embryonic stem cells.Nat ProtocElling, U., Woods, M., Forment, JV., Fu, B., Yang, F., Ng, BL., Vicente, JR., Adams, DJ., Doe, B., Jackson, SP., Penninger, JM., Balmus, G.
2019CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci.Nat CommunChylinski, K., Hubmann, M., Hanna, RE., Yanchus, C., Michlits, G., Uijttewaal, ECH., Doench, J., Schramek, D., Elling, U.
2019The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders.ElifeAng, CE., Ma, Q., Wapinski, OL., Fan, S., Flynn, RA., Lee, QY., Coe, B., Onoguchi, M., Olmos, VH., Do, BT., Dukes-Rimsky, L., Xu, J., Tanabe, K., Wang, L., Elling, U., Penninger, JM., Zhao, Y., Qu, K., Eichler, EE., Srivastava, A., Wernig, M., Chang, HY.
2018Loss of function mutations in VARS encoding cytoplasmic valyl-tRNA synthetase cause microcephaly, seizures, and progressive cerebral atrophy.Hum GenetStephen, J., Nampoothiri, S., Banerjee, A., Tolman, NJ., Penninger, JM., Elling, U., Agu, CA., Burke, JD., Devadathan, K., Kannan, R., Huang, Y., Steinbach, PJ., Martinis, SA., Gahl, WA., Malicdan, MCV.
2018Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells.OncotargetHorn, M., Kroef, V., Allmeroth, K., Schuller, N., Miethe, S., Peifer, M., Penninger, JM., Elling, U., Denzel, MS.
2018Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency.Cell Stem CellMor, N., Rais, Y., Sheban, D., Peles, S., Aguilera-Castrejon, A., Zviran, A., Elinger, D., Viukov, S., Geula, S., Krupalnik, V., Zerbib, M., Chomsky, E., Lasman, L., Shani, T., Bayerl, J., Gafni, O., Hanna, S., Buenrostro, JD., Hagai, T., Masika, H., Vainorius, G., Bergman, Y., Greenleaf, WJ., Esteban, MA., Elling, U., Levin, Y., Massarwa, R., Merbl, Y., Novershtern, N., Hanna, JH.
2017Comparative glycoproteomics of stem cells identifies new players in ricin toxicity.NatureStadlmann, J., Taubenschmid, J., Wenzel, D., Gattinger, A., Dürnberger, G., Dusberger, F., Elling, U., Mach, L., Mechtler, K., Penninger, JM.
2017A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.NatureElling, U., Wimmer, RA., Leibbrandt, A., Burkard, T., Michlits, G., Leopoldi, A., Micheler, T., Abdeen, D., Zhuk, S., Aspalter, IM., Handl, C., Liebergesell, J., Hubmann, M., Husa, AM., Kinzer, M., Schuller, N., Wetzel, E., van de Loo, N., Martinez, JAZ., Estoppey, D., Riedl, R., Yang, F., Fu, B., Dechat, T., Ivics, Z., Agu, CA., Bell, O., Blaas, D., Gerhardt, H., Hoepfner, D., Stark, A., Penninger, JM.
2017CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.Nat MethodsMichlits, G., Hubmann, M., Wu, SH., Vainorius, G., Budusan, E., Zhuk, S., Burkard, TR., Novatchkova, M., Aichinger, M., Lu, Y., Reece-Hoyes, J., Nitsch, R., Schramek, D., Hoepfner, D., Elling, U.
2017A vital sugar code for ricin toxicity.Cell ResTaubenschmid, J., Stadlmann, J., Jost, M., Klokk, TI., Rillahan, CD., Leibbrandt, A., Mechtler, K., Paulson, JC., Jude, J., Zuber, J., Sandvig, K., Elling, U., Marquardt, T., Thiel, C., Koerner, C., Penninger, JM.
2017DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells.Cell Stem CellChoi, J., Clement, K., Huebner, AJ., Webster, J., Rose, CM., Brumbaugh, J., Walsh, RM., Lee, S., Savol, A., Etchegaray, JP., Gu, H., Boyle, P., Elling, U., Mostoslavsky, R., Sadreyev, R., Park, PJ., Gygi, SP., Meissner, A., Hochedlinger, K.
2016Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.DevelopmentBreuss, M., Fritz, T., Gstrein, T., Chan, K., Ushakova, L., Yu, N., Vonberg, FW., Werner, B., Elling, U., Keays, DA.
2016The mevalonate pathway regulates primitive streak formation via protein farnesylation.Sci RepOkamoto-Uchida, Y., Yu, R., Miyamura, N., Arima, N., Ishigami-Yuasa, M., Kagechika, H., Yoshida, S., Hosoya, T., Nawa, M., Kasama, T., Asaoka, Y., Alois, RW., Elling, U., Penninger, JM., Nishina, S., Azuma, N., Nishina, H.
2015The histone chaperone CAF-1 safeguards somatic cell identity.NatureCheloufi, S., Elling, U., Hopfgartner, B., Jung, YL., Murn, J., Ninova, M., Hubmann, M., Badeaux, AI., Euong Ang, C., Tenen, D., Wesche, DJ., Abazova, N., Hogue, M., Tasdemir, N., Brumbaugh, J., Rathert, P., Jude, J., Ferrari, F., Blanco, A., Fellner, M., Wenzel, D., Zinner, M., Vidal, SE., Bell, O., Stadtfeld, M., Chang, HY., Almouzni, G., Lowe, SW., Rinn, J., Wernig, M., Aravin, A., Shi, Y., Park, PJ., Penninger, JM., Zuber, J., Hochedlinger, K.