| 2023 | A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors. | EMBO Mol Med | Taubenschmid-Stowers, J., Orthofer, M., Laemmerer, A., Krauditsch, C., Rózsová, M., Studer, C., Lötsch, D., Gojo, J., Gabler, L., Dyczynski, M., Efferth, T., Hagelkruys, A., Widhalm, G., Peyrl, A., Spiegl-Kreinecker, S., Hoepfner, D., Bian, S., Berger, W., Knoblich, JA., Elling, U., Horn, M., Penninger, JM. |
| 2023 | ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers. | Nat Cell Biol | Yelagandula, R., Stecher, K., Novatchkova, M., Michetti, L., Michlits, G., Wang, J., Hofbauer, P., Vainorius, G., Pribitzer, C., Isbel, L., Mendjan, S., Schübeler, D., Elling, U., Brennecke, J., Bell, O. |
| 2023 | Low-density lipoprotein receptor-related protein 1 (LRP1) as an auxiliary host factor for RNA viruses. | Life Sci Alliance | Devignot, S., Sha, TW., Burkard, TR., Schmerer, P., Hagelkruys, A., Mirazimi, A., Elling, U., Penninger, JM., Weber, F. |
| 2023 | FAM3C/ILEI protein is elevated in psoriatic lesions and triggers psoriasiform hyperproliferation in mice. | EMBO Mol Med | Malik, B., Vokic, I., Mohr, T., Poppelaars, M., Holcmann, M., Novoszel, P., Timelthaler, G., Lendl, T., Krauss, D., Elling, U., Mildner, M., Penninger, JM., Petzelbauer, P., Sibilia, M., Csiszar, A. |
| 2022 | The HUSH complex controls brain architecture and protocadherin fidelity. | Sci Adv | Hagelkruys, A., Horrer, M., Taubenschmid-Stowers, J., Kavirayani, A., Novatchkova, M., Orthofer, M., Pai, TP., Cikes, D., Zhuk, S., Balmaña, M., Esk, C., Koglgruber, R., Moeseneder, P., Lazovic, J., Zopf, LM., Cronin, SJF., Elling, U., Knoblich, JA., Penninger, JM. |
| 2022 | Transient upregulation of IRF1 during exit from naive pluripotency confers viral protection. | EMBO Rep | Romeike, M., Spach, S., Huber, M., Feng, S., Vainorius, G., Elling, U., Versteeg, GA., Buecker, C. |
| 2022 | Redirecting Imipramine against Bluetongue Virus Infection: Insights from a Genome-wide Haploid Screening Study. | Pathogens | John, L., Vernersson, C., Kwon, H., Elling, U., Penninger, JM., Mirazimi, A. |
| 2022 | GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway. | Elife | Kroef, V., Ruegenberg, S., Horn, M., Allmeroth, K., Ebert, L., Bozkus, S., Miethe, S., Elling, U., Schermer, B., Baumann, U., Denzel, MS. |
| 2022 | DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions. | Nat Genet | Butz, S., Schmolka, N., Karemaker, ID., Villaseñor, R., Schwarz, I., Domcke, S., Uijttewaal, ECH., Jude, J., Lienert, F., Krebs, AR., de Wagenaar, NP., Bao, X., Zuber, J., Elling, U., Schübeler, D., Baubec, T. |
| 2021 | The BTB-domain transcription factor ZBTB2 recruits chromatin remodelers and a histone chaperone during the exit from pluripotency. | J Biol Chem | Olivieri, D., Paramanathan, S., Bardet, AF., Hess, D., Smallwood, SA., Elling, U., Betschinger, J. |
| 2021 | Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq. | Nat Commun | Yelagandula, R., Bykov, A., Vogt, A., Heinen, R., Özkan, E., Strobl, MM., Baar, JC., Uzunova, K., Hajdusits, B., Kordic, D., Suljic, E., Kurtovic-Kozaric, A., Izetbegovic, S., Schaeffer, J., Hufnagl, P., Zoufaly, A., Seitz, T., Födinger, M., Allerberger, F., Stark, A., Cochella, L., Elling, U. |
| 2020 | A human tissue screen identifies a regulator of ER secretion as a brain-size determinant. | Science | Esk, C., Lindenhofer, D., Haendeler, S., Wester, RA., Pflug, F., Schroeder, B., Bagley, JA., Elling, U., Zuber, J., von Haeseler, A., Knoblich, JA. |
| 2020 | Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles. | Nat Methods | Michlits, G., Jude, J., Hinterndorfer, M., de Almeida, M., Vainorius, G., Hubmann, M., Neumann, T., Schleiffer, A., Burkard, TR., Fellner, M., Gijsbertsen, M., Traunbauer, A., Zuber, J., Elling, U. |
| 2019 | The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders. | Elife | Ang, CE., Ma, Q., Wapinski, OL., Fan, S., Flynn, RA., Lee, QY., Coe, B., Onoguchi, M., Olmos, VH., Do, BT., Dukes-Rimsky, L., Xu, J., Tanabe, K., Wang, L., Elling, U., Penninger, JM., Zhao, Y., Qu, K., Eichler, EE., Srivastava, A., Wernig, M., Chang, HY. |
| 2019 | Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing. | Nat Commun | Moussa, HF., Bsteh, D., Yelagandula, R., Pribitzer, C., Stecher, K., Bartalska, K., Michetti, L., Wang, J., Zepeda-Martinez, JA., Elling, U., Stuckey, JI., James, LI., Frye, SV., Bell, O. |
| 2019 | CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci. | Nat Commun | Chylinski, K., Hubmann, M., Hanna, RE., Yanchus, C., Michlits, G., Uijttewaal, ECH., Doench, J., Schramek, D., Elling, U. |
| 2019 | Derivation and maintenance of mouse haploid embryonic stem cells. | Nat Protoc | Elling, U., Woods, M., Forment, JV., Fu, B., Yang, F., Ng, BL., Vicente, JR., Adams, DJ., Doe, B., Jackson, SP., Penninger, JM., Balmus, G. |
| 2019 | Using Functional Genetics in Haploid Cells for Drug Target Identification. | Methods Mol Biol | Volz, JC., Schuller, N., Elling, U. |
| 2018 | Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency. | Cell Stem Cell | Mor, N., Rais, Y., Sheban, D., Peles, S., Aguilera-Castrejon, A., Zviran, A., Elinger, D., Viukov, S., Geula, S., Krupalnik, V., Zerbib, M., Chomsky, E., Lasman, L., Shani, T., Bayerl, J., Gafni, O., Hanna, S., Buenrostro, JD., Hagai, T., Masika, H., Vainorius, G., Bergman, Y., Greenleaf, WJ., Esteban, MA., Elling, U., Levin, Y., Massarwa, R., Merbl, Y., Novershtern, N., Hanna, JH. |
| 2018 | Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells. | Oncotarget | Horn, M., Kroef, V., Allmeroth, K., Schuller, N., Miethe, S., Peifer, M., Penninger, JM., Elling, U., Denzel, MS. |
