List of Publications

2015Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.Proc Natl Acad Sci U S AKoo, BK., van Es, JH., van den Born, M., Clevers, H.
2021Organoids: ready for the revolution?J Mol Med (Berl)Koo, BK., Bartfeld, S., Alev, C.
2016Organoids: A new in vitro model system for biomedical science and disease modelling and promising source for cell-based transplantation.Dev BiolKoo, BK., Huch, M.
2017One-step generation of conditional and reversible gene knockouts.Nat MethodsAndersson-Rolf, A., Mustata, RC., Merenda, A., Kim, J., Perera, S., Grego, T., Andrews, K., Tremble, K., Silva, JC., Fink, J., Skarnes, WC., Koo, BK.
2012Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer.J Clin InvestKim, HA., Koo, BK., Cho, JH., Kim, YY., Seong, J., Chang, HJ., Oh, YM., Stange, DE., Park, JG., Hwang, D., Kong, YY.
2009Notch signaling promotes the generation of EphrinB1-positive intestinal epithelial cells.GastroenterologyKoo, BK., Lim, HS., Chang, HJ., Yoon, MJ., Choi, Y., Kong, MP., Kim, CH., Kim, JM., Park, JG., Kong, YY.
2020Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses.mBioHosmillo, M., Chaudhry, Y., Nayak, K., Sorgeloos, F., Koo, BK., Merenda, A., Lillestol, R., Drumright, L., Zilbauer, M., Goodfellow, I.
2021Niche-specific MHC II and PD-L1 regulate CD4+CD8αα+ intraepithelial lymphocyte differentiation.J Exp MedMoon, S., Park, Y., Hyeon, S., Kim, YM., Kim, JH., Kim, H., Park, S., Lee, KJ., Koo, BK., Ha, SJ., Lee, SW.
2006Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1.J Biol ChemSong, R., Koo, BK., Yoon, KJ., Yoon, MJ., Yoo, KW., Kim, HT., Oh, HJ., Kim, YY., Han, JK., Kim, CH., Kong, YY.
2019Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations.GastroenterologySeidlitz, T., Chen, YT., Uhlemann, H., Schölch, S., Kochall, S., Merker, SR., Klimova, A., Hennig, A., Schweitzer, C., Pape, K., Baretton, GB., Welsch, T., Aust, DE., Weitz, J., Koo, BK., Stange, DE.
2018Morphological alterations of cultured human colorectal matched tumour and healthy organoids.OncotargetKashfi, SMH., Almozyan, S., Jinks, N., Koo, BK., Nateri, AS.
2015Modeling mouse and human development using organoid cultures.DevelopmentHuch, M., Koo, BK.
2019Modeling Host-Virus Interactions in Viral Infectious Diseases Using Stem-Cell-Derived Systems and CRISPR/Cas9 Technology.VirusesKim, J., Koo, BK., Yoon, KJ.
2005Mind bomb-2 is an E3 ligase for Notch ligand.J Biol ChemKoo, BK., Yoon, KJ., Yoo, KW., Lim, HS., Song, R., So, JH., Kim, CH., Kong, YY.
2008Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.Mol Cell BiolYoon, MJ., Koo, BK., Song, R., Jeong, HW., Shin, J., Kim, YW., Kong, YY., Suh, PG.
2008Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells.NeuronYoon, KJ., Koo, BK., Im, SK., Jeong, HW., Ghim, J., Kwon, MC., Moon, JS., Miyata, T., Kong, YY.
2005Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.DevelopmentKoo, BK., Lim, HS., Song, R., Yoon, MJ., Yoon, KJ., Moon, JS., Kim, YW., Kwon, MC., Yoo, KW., Kong, MP., Lee, J., Chitnis, AB., Kim, CH., Kong, YY.
2008Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell development.J Exp MedSong, R., Kim, YW., Koo, BK., Jeong, HW., Yoon, MJ., Yoon, KJ., Jun, DJ., Im, SK., Shin, J., Kong, MP., Kim, KT., Yoon, K., Kong, YY.
2017Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium.Nat Cell BiolTurco, MY., Gardner, L., Hughes, J., Cindrova-Davies, T., Gomez, MJ., Farrell, L., Hollinshead, M., Marsh, SGE., Brosens, JJ., Critchley, HO., Simons, BD., Hemberger, M., Koo, BK., Moffett, A., Burton, GJ.
2019Lineage Tracing: Computational Reconstruction Goes Beyond the Limit of Imaging.Mol CellsWu, SS., Lee, JH., Koo, BK.