List of Publications

YearTitleJournalAuthors
2018ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling.Proc Natl Acad Sci U S AHarris, A., Siggers, P., Corrochano, S., Warr, N., Sagar, D., Grimes, DT., Suzuki, M., Burdine, RD., Cong, F., Koo, BK., Clevers, H., Stévant, I., Nef, S., Wells, S., Brauner, R., Ben Rhouma, B., Belguith, N., Eozenou, C., Bignon-Topalovic, J., Bashamboo, A., McElreavey, K., Greenfield, A.
2021Wnt/β-catenin signaling: structure, assembly and endocytosis of the signalosome.Dev Growth DifferColozza, G., Koo, BK.
2021Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway.EMBO RepColozza, G., Koo, BK.
2012Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.NatureKoo, BK., Spit, M., Jordens, I., Low, TY., Stange, DE., van de Wetering, M., van Es, JH., Mohammed, S., Heck, AJ., Maurice, MM., Clevers, H.
2011The WNT antagonist Dickkopf2 promotes angiogenesis in rodent and human endothelial cells.J Clin InvestMin, JK., Park, H., Choi, HJ., Kim, Y., Pyun, BJ., Agrawal, V., Song, BW., Jeon, J., Maeng, YS., Rho, SS., Shim, S., Chai, JH., Koo, BK., Hong, HJ., Yun, CO., Choi, C., Kim, YM., Hwang, KC., Kwon, YG.
2012The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.EMBO JMuñoz, J., Stange, DE., Schepers, AG., van de Wetering, M., Koo, BK., Itzkovitz, S., Volckmann, R., Kung, KS., Koster, J., Radulescu, S., Myant, K., Versteeg, R., Sansom, OJ., van Es, JH., Barker, N., van Oudenaarden, A., Mohammed, S., Heck, AJ., Clevers, H.
2018Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer.Open BiolSpit, M., Koo, BK., Maurice, MM.
2011Survival and differentiation of mammary epithelial cells in mammary gland development require nuclear retention of Id2 due to RANK signaling.Mol Cell BiolKim, NS., Kim, HT., Kwon, MC., Choi, SW., Kim, YY., Yoon, KJ., Koo, BK., Kong, MP., Shin, J., Cho, Y., Kong, YY.
2014Stem cells marked by the R-spondin receptor LGR5.GastroenterologyKoo, BK., Clevers, H.
2017Stem Cells in Repair of Gastrointestinal Epithelia.Physiology (Bethesda)Andersson-Rolf, A., Zilbauer, M., Koo, BK., Clevers, H.
2015 Stem cell-derived organoid cultures and genome editing tools. Cell Gene Therapy InsightsAndersson-Rolf A, Koo BK
2006Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish.FEBS LettYoo, KW., Kim, EH., Jung, SH., Rhee, M., Koo, BK., Yoon, KJ., Kong, YY., Kim, CH.
2016Simultaneous paralogue knockout using a CRISPR-concatemer in mouse small intestinal organoids.Dev BiolAndersson-Rolf, A., Merenda, A., Mustata, RC., Li, T., Dietmann, S., Koo, BK.
2020RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.EMBO JSpit, M., Fenderico, N., Jordens, I., Radaszkiewicz, T., Lindeboom, RG., Bugter, JM., Cristobal, A., Ootes, L., van Osch, M., Janssen, E., Boonekamp, KE., Hanakova, K., Potesil, D., Zdrahal, Z., Boj, SF., Medema, JP., Bryja, V., Koo, BK., Vermeulen, M., Maurice, MM.
2013Retroviral gene expression control in primary organoid cultures.Curr Protoc Stem Cell BiolKoo, BK., Sasselli, V., Clevers, H.
2006Receptor activator of NF-kappaB ligand regulates the proliferation of mammary epithelial cells via Id2.Mol Cell BiolKim, NS., Kim, HJ., Koo, BK., Kwon, MC., Kim, YW., Cho, Y., Yokota, Y., Penninger, JM., Kong, YY.
2016Rapid, one-step generation of biallelic conditional gene knockouts.BioRxivAndersson-Rolf A, Mustata RC, Merenda A, Perera S, Grego T, Kim J, Andrews K, Fink J, Skarnes WC, Koo BK.
2021Post-translational Wnt receptor regulation: Is the fog slowly clearing?BioessaysTsukiyama, T., Koo, BK., Hatakeyama, S.
2015Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.Proc Natl Acad Sci U S AKoo, BK., van Es, JH., van den Born, M., Clevers, H.
2021Organoids: ready for the revolution?J Mol Med (Berl)Koo, BK., Bartfeld, S., Alev, C.