List of Publications

YearTitleJournalAuthors
2005Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.DevelopmentKoo, BK., Lim, HS., Song, R., Yoon, MJ., Yoon, KJ., Moon, JS., Kim, YW., Kwon, MC., Yoo, KW., Kong, MP., Lee, J., Chitnis, AB., Kim, CH., Kong, YY.
2009Notch signaling promotes the generation of EphrinB1-positive intestinal epithelial cells.GastroenterologyKoo, BK., Lim, HS., Chang, HJ., Yoon, MJ., Choi, Y., Kong, MP., Kim, CH., Kim, JM., Park, JG., Kong, YY.
2016Organoids: A new in vitro model system for biomedical science and disease modelling and promising source for cell-based transplantation.Dev BiolKoo, BK., Huch, M.
2014Stem cells marked by the R-spondin receptor LGR5.GastroenterologyKoo, BK., Clevers, H.
2021Organoids: ready for the revolution?J Mol Med (Berl)Koo, BK., Bartfeld, S., Alev, C.
2018Generation of FLIP and FLIP-FlpE Targeting Vectors for Biallelic Conditional and Reversible Gene Knockouts in Mouse and Human Cells.Methods Mol BiolKoo, BK.
2008Defective Notch activation in microenvironment leads to myeloproliferative disease.BloodKim, YW., Koo, BK., Jeong, HW., Yoon, MJ., Song, R., Shin, J., Jeong, DC., Kim, SH., Kong, YY.
2011Survival and differentiation of mammary epithelial cells in mammary gland development require nuclear retention of Id2 due to RANK signaling.Mol Cell BiolKim, NS., Kim, HT., Kwon, MC., Choi, SW., Kim, YY., Yoon, KJ., Koo, BK., Kong, MP., Shin, J., Cho, Y., Kong, YY.
2006Receptor activator of NF-kappaB ligand regulates the proliferation of mammary epithelial cells via Id2.Mol Cell BiolKim, NS., Kim, HJ., Koo, BK., Kwon, MC., Kim, YW., Cho, Y., Yokota, Y., Penninger, JM., Kong, YY.
2019Modeling Host-Virus Interactions in Viral Infectious Diseases Using Stem-Cell-Derived Systems and CRISPR/Cas9 Technology.VirusesKim, J., Koo, BK., Yoon, KJ.
2020Human organoids: model systems for human biology and medicine.Nat Rev Mol Cell BiolKim, J., Koo, BK., Knoblich, JA.
2012Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer.J Clin InvestKim, HA., Koo, BK., Cho, JH., Kim, YY., Seong, J., Chang, HJ., Oh, YM., Stange, DE., Park, JG., Hwang, D., Kong, YY.
2018Morphological alterations of cultured human colorectal matched tumour and healthy organoids.OncotargetKashfi, SMH., Almozyan, S., Jinks, N., Koo, BK., Nateri, AS.
2009Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice.J Clin InvestJeong, HW., Jeon, US., Koo, BK., Kim, WY., Im, SK., Shin, J., Cho, Y., Kim, J., Kong, YY.
2015Modeling mouse and human development using organoid cultures.DevelopmentHuch, M., Koo, BK.
2018DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.GastroenterologyHowell, KJ., Kraiczy, J., Nayak, KM., Gasparetto, M., Ross, A., Lee, C., Mak, TN., Koo, BK., Kumar, N., Lawley, T., Sinha, A., Rosenstiel, P., Heuschkel, R., Stegle, O., Zilbauer, M.
2020Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses.mBioHosmillo, M., Chaudhry, Y., Nayak, K., Sorgeloos, F., Koo, BK., Merenda, A., Lillestol, R., Drumright, L., Zilbauer, M., Goodfellow, I.
2013ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response.Cell RepHeijmans, J., van Lidth de Jeude, JF., Koo, BK., Rosekrans, SL., Wielenga, MC., van de Wetering, M., Ferrante, M., Lee, AS., Onderwater, JJ., Paton, JC., Paton, AW., Mommaas, AM., Kodach, LL., Hardwick, JC., Hommes, DW., Clevers, H., Muncan, V., van den Brink, GR.
2018ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling.Proc Natl Acad Sci U S AHarris, A., Siggers, P., Corrochano, S., Warr, N., Sagar, D., Grimes, DT., Suzuki, M., Burdine, RD., Cong, F., Koo, BK., Clevers, H., Stévant, I., Nef, S., Wells, S., Brauner, R., Ben Rhouma, B., Belguith, N., Eozenou, C., Bignon-Topalovic, J., Bashamboo, A., McElreavey, K., Greenfield, A.
2019Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.Cell Stem CellHan, S., Fink, J., Jörg, DJ., Lee, E., Yum, MK., Chatzeli, L., Merker, SR., Josserand, M., Trendafilova, T., Andersson-Rolf, A., Dabrowska, C., Kim, H., Naumann, R., Lee, JH., Sasaki, N., Mort, RL., Basak, O., Clevers, H., Stange, DE., Philpott, A., Kim, JK., Simons, BD., Koo, BK.