List of Publications

YearTitleJournalAuthors
2008Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.Mol Cell BiolYoon, MJ., Koo, BK., Song, R., Jeong, HW., Shin, J., Kim, YW., Kong, YY., Suh, PG.
2008Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells.NeuronYoon, KJ., Koo, BK., Im, SK., Jeong, HW., Ghim, J., Kwon, MC., Moon, JS., Miyata, T., Kong, YY.
2006Snx5, as a Mind bomb-binding protein, is expressed in hematopoietic and endothelial precursor cells in zebrafish.FEBS LettYoo, KW., Kim, EH., Jung, SH., Rhee, M., Koo, BK., Yoon, KJ., Kong, YY., Kim, CH.
2019Lineage Tracing: Computational Reconstruction Goes Beyond the Limit of Imaging.Mol CellsWu, SS., Lee, JH., Koo, BK.
2012A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.Mol Cell Biolvan Es, JH., Haegebarth, A., Kujala, P., Itzkovitz, S., Koo, BK., Boj, SF., Korving, J., van den Born, M., van Oudenaarden, A., Robine, S., Clevers, H.
2017Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium.Nat Cell BiolTurco, MY., Gardner, L., Hughes, J., Cindrova-Davies, T., Gomez, MJ., Farrell, L., Hollinshead, M., Marsh, SGE., Brosens, JJ., Critchley, HO., Simons, BD., Hemberger, M., Koo, BK., Moffett, A., Burton, GJ.
2020A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.Nat CommunTsukiyama, T., Zou, J., Kim, J., Ogamino, S., Shino, Y., Masuda, T., Merenda, A., Matsumoto, M., Fujioka, Y., Hirose, T., Terai, S., Takahashi, H., Ishitani, T., Nakayama, KI., Ohba, Y., Koo, BK., Hatakeyama, S.
2021Post-translational Wnt receptor regulation: Is the fog slowly clearing?BioessaysTsukiyama, T., Koo, BK., Hatakeyama, S.
2021Genetic engineering in organoids.J Mol Med (Berl)Teriyapirom, I., Batista-Rocha, AS., Koo, BK.
2020Human Microphysiological Models of Intestinal Tissue and Gut Microbiome.Front Bioeng BiotechnolSteinway, SN., Saleh, J., Koo, BK., Delacour, D., Kim, DH.
2013Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium.CellStange, DE., Koo, BK., Huch, M., Sibbel, G., Basak, O., Lyubimova, A., Kujala, P., Bartfeld, S., Koster, J., Geahlen, JH., Peters, PJ., van Es, JH., van de Wetering, M., Mills, JC., Clevers, H.
2010Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain.GutStange, DE., Engel, F., Longerich, T., Koo, BK., Koch, M., Delhomme, N., Aigner, M., Toedt, G., Schirmacher, P., Lichter, P., Weitz, J., Radlwimmer, B.
2018Tales from the crypt: intestinal niche signals in tissue renewal, plasticity and cancer.Open BiolSpit, M., Koo, BK., Maurice, MM.
2020RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.EMBO JSpit, M., Fenderico, N., Jordens, I., Radaszkiewicz, T., Lindeboom, RG., Bugter, JM., Cristobal, A., Ootes, L., van Osch, M., Janssen, E., Boonekamp, KE., Hanakova, K., Potesil, D., Zdrahal, Z., Boj, SF., Medema, JP., Bryja, V., Koo, BK., Vermeulen, M., Maurice, MM.
2006Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1.J Biol ChemSong, R., Koo, BK., Yoon, KJ., Yoon, MJ., Yoo, KW., Kim, HT., Oh, HJ., Kim, YY., Han, JK., Kim, CH., Kong, YY.
2008Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell development.J Exp MedSong, R., Kim, YW., Koo, BK., Jeong, HW., Yoon, MJ., Yoon, KJ., Jun, DJ., Im, SK., Shin, J., Kong, MP., Kim, KT., Yoon, K., Kong, YY.
2019Human gastric cancer modelling using organoids.GutSeidlitz, T., Merker, SR., Rothe, A., Zakrzewski, F., von Neubeck, C., Grützmann, K., Sommer, U., Schweitzer, C., Schölch, S., Uhlemann, H., Gaebler, AM., Werner, K., Krause, M., Baretton, GB., Welsch, T., Koo, BK., Aust, DE., Klink, B., Weitz, J., Stange, DE.
2020Gastric organoids-an in vitro model system for the study of gastric development and road to personalized medicine.Cell Death DifferSeidlitz, T., Koo, BK., Stange, DE.
2019Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations.GastroenterologySeidlitz, T., Chen, YT., Uhlemann, H., Schölch, S., Kochall, S., Merker, SR., Klimova, A., Hennig, A., Schweitzer, C., Pape, K., Baretton, GB., Welsch, T., Aust, DE., Weitz, J., Koo, BK., Stange, DE.
2013Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients.Cell Stem CellSchwank, G., Koo, BK., Sasselli, V., Dekkers, JF., Heo, I., Demircan, T., Sasaki, N., Boymans, S., Cuppen, E., van der Ent, CK., Nieuwenhuis, EE., Beekman, JM., Clevers, H.