List of Publications

2012A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.Mol Cell Biolvan Es, JH., Haegebarth, A., Kujala, P., Itzkovitz, S., Koo, BK., Boj, SF., Korving, J., van den Born, M., van Oudenaarden, A., Robine, S., Clevers, H.
2008A crucial role of WW45 in developing epithelial tissues in the mouse.EMBO JLee, JH., Kim, TS., Yang, TH., Koo, BK., Oh, SP., Lee, KP., Oh, HJ., Lee, SH., Kong, YY., Kim, JM., Lim, DS.
2020A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.Nat CommunTsukiyama, T., Zou, J., Kim, J., Ogamino, S., Shino, Y., Masuda, T., Merenda, A., Matsumoto, M., Fujioka, Y., Hirose, T., Terai, S., Takahashi, H., Ishitani, T., Nakayama, KI., Ohba, Y., Koo, BK., Hatakeyama, S.
2017A Protocol for Multiple Gene Knockout in Mouse Small Intestinal Organoids Using a CRISPR-concatemer.J Vis ExpMerenda, A., Andersson-Rolf, A., Mustata, RC., Li, T., Kim, H., Koo, BK.
2014A video protocol of retroviral infection in primary intestinal organoid culture.J Vis ExpAndersson-Rolf, A., Fink, J., Mustata, RC., Koo, BK.
2019A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis.Genes DevBasham, KJ., Rodriguez, S., Turcu, AF., Lerario, AM., Logan, CY., Rysztak, MR., Gomez-Sanchez, CE., Breault, DT., Koo, BK., Clevers, H., Nusse, R., Val, P., Hammer, GD.
2017Adult gastric stem cells and their niches.Wiley Interdiscip Rev Dev BiolBartfeld, S., Koo, BK.
2015Adult stem cell lineage tracing and deep tissue imaging.BMB RepFink, J., Andersson-Rolf, A., Koo, BK.
2007An obligatory role of mind bomb-1 in notch signaling of mammalian development.PLoS OneKoo, BK., Yoon, MJ., Yoon, KJ., Im, SK., Kim, YY., Kim, CH., Suh, PG., Jan, YN., Kong, YY.
2015Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.Cell Stem CellSchuijers, J., Junker, JP., Mokry, M., Hatzis, P., Koo, BK., Sasselli, V., van der Flier, LG., Cuppen, E., van Oudenaarden, A., Clevers, H.
2016Clonal Evolution of Stem Cells in the Gastrointestinal Tract.Adv Exp Med BiolFink, J., Koo, BK.
2011Controlled gene expression in primary Lgr5 organoid cultures.Nat MethodsKoo, BK., Stange, DE., Sato, T., Karthaus, W., Farin, HF., Huch, M., van Es, JH., Clevers, H.
2008Crif1 is a novel transcriptional coactivator of STAT3.EMBO JKwon, MC., Koo, BK., Moon, JS., Kim, YY., Park, KC., Kim, NS., Kwon, MY., Kong, MP., Yoon, KJ., Im, SK., Ghim, J., Han, YM., Jang, SK., Shong, M., Kong, YY.
2016Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation.Nat ProtocBroutier, L., Andersson-Rolf, A., Hindley, CJ., Boj, SF., Clevers, H., Koo, BK., Huch, M.
2008Defective Notch activation in microenvironment leads to myeloproliferative disease.BloodKim, YW., Koo, BK., Jeong, HW., Yoon, MJ., Song, R., Shin, J., Jeong, DC., Kim, SH., Kong, YY.
2020Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss.Sci RepMorkmued, S., Clauss, F., Schuhbaur, B., Fraulob, V., Mathieu, E., Hemmerlé, J., Clevers, H., Koo, BK., Dollé, P., Bloch-Zupan, A., Niederreither, K.
2019Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells.Cell Stem CellHan, S., Fink, J., Jörg, DJ., Lee, E., Yum, MK., Chatzeli, L., Merker, SR., Josserand, M., Trendafilova, T., Andersson-Rolf, A., Dabrowska, C., Kim, H., Naumann, R., Lee, JH., Sasaki, N., Mort, RL., Basak, O., Clevers, H., Stange, DE., Philpott, A., Kim, JK., Simons, BD., Koo, BK.
2013Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium.CellStange, DE., Koo, BK., Huch, M., Sibbel, G., Basak, O., Lyubimova, A., Kujala, P., Bartfeld, S., Koster, J., Geahlen, JH., Peters, PJ., van Es, JH., van de Wetering, M., Mills, JC., Clevers, H.
2018Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis.CellNanki, K., Toshimitsu, K., Takano, A., Fujii, M., Shimokawa, M., Ohta, Y., Matano, M., Seino, T., Nishikori, S., Ishikawa, K., Kawasaki, K., Togasaki, K., Takahashi, S., Sukawa, Y., Ishida, H., Sugimoto, S., Kawakubo, H., Kim, J., Kitagawa, Y., Sekine, S., Koo, BK., Kanai, T., Sato, T.
2018DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.GastroenterologyHowell, KJ., Kraiczy, J., Nayak, KM., Gasparetto, M., Ross, A., Lee, C., Mak, TN., Koo, BK., Kumar, N., Lawley, T., Sinha, A., Rosenstiel, P., Heuschkel, R., Stegle, O., Zilbauer, M.