List of Publications

2020Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses.mBioHosmillo, M., Chaudhry, Y., Nayak, K., Sorgeloos, F., Koo, BK., Merenda, A., Lillestol, R., Drumright, L., Zilbauer, M., Goodfellow, I.
2018DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.GastroenterologyHowell, KJ., Kraiczy, J., Nayak, KM., Gasparetto, M., Ross, A., Lee, C., Mak, TN., Koo, BK., Kumar, N., Lawley, T., Sinha, A., Rosenstiel, P., Heuschkel, R., Stegle, O., Zilbauer, M.
2015Modeling mouse and human development using organoid cultures.DevelopmentHuch, M., Koo, BK.
2009Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice.J Clin InvestJeong, HW., Jeon, US., Koo, BK., Kim, WY., Im, SK., Shin, J., Cho, Y., Kim, J., Kong, YY.
2018Morphological alterations of cultured human colorectal matched tumour and healthy organoids.OncotargetKashfi, SMH., Almozyan, S., Jinks, N., Koo, BK., Nateri, AS.
2012Notch1 counteracts WNT/β-catenin signaling through chromatin modification in colorectal cancer.J Clin InvestKim, HA., Koo, BK., Cho, JH., Kim, YY., Seong, J., Chang, HJ., Oh, YM., Stange, DE., Park, JG., Hwang, D., Kong, YY.
2020Human organoids: model systems for human biology and medicine.Nat Rev Mol Cell BiolKim, J., Koo, BK., Knoblich, JA.
2019Modeling Host-Virus Interactions in Viral Infectious Diseases Using Stem-Cell-Derived Systems and CRISPR/Cas9 Technology.VirusesKim, J., Koo, BK., Yoon, KJ.
2006Receptor activator of NF-kappaB ligand regulates the proliferation of mammary epithelial cells via Id2.Mol Cell BiolKim, NS., Kim, HJ., Koo, BK., Kwon, MC., Kim, YW., Cho, Y., Yokota, Y., Penninger, JM., Kong, YY.
2011Survival and differentiation of mammary epithelial cells in mammary gland development require nuclear retention of Id2 due to RANK signaling.Mol Cell BiolKim, NS., Kim, HT., Kwon, MC., Choi, SW., Kim, YY., Yoon, KJ., Koo, BK., Kong, MP., Shin, J., Cho, Y., Kong, YY.
2008Defective Notch activation in microenvironment leads to myeloproliferative disease.BloodKim, YW., Koo, BK., Jeong, HW., Yoon, MJ., Song, R., Shin, J., Jeong, DC., Kim, SH., Kong, YY.
2018Generation of FLIP and FLIP-FlpE Targeting Vectors for Biallelic Conditional and Reversible Gene Knockouts in Mouse and Human Cells.Methods Mol BiolKoo, BK.
2021Organoids: ready for the revolution?J Mol Med (Berl)Koo, BK., Bartfeld, S., Alev, C.
2014Stem cells marked by the R-spondin receptor LGR5.GastroenterologyKoo, BK., Clevers, H.
2016Organoids: A new in vitro model system for biomedical science and disease modelling and promising source for cell-based transplantation.Dev BiolKoo, BK., Huch, M.
2009Notch signaling promotes the generation of EphrinB1-positive intestinal epithelial cells.GastroenterologyKoo, BK., Lim, HS., Chang, HJ., Yoon, MJ., Choi, Y., Kong, MP., Kim, CH., Kim, JM., Park, JG., Kong, YY.
2005Mind bomb 1 is essential for generating functional Notch ligands to activate Notch.DevelopmentKoo, BK., Lim, HS., Song, R., Yoon, MJ., Yoon, KJ., Moon, JS., Kim, YW., Kwon, MC., Yoo, KW., Kong, MP., Lee, J., Chitnis, AB., Kim, CH., Kong, YY.
2013Retroviral gene expression control in primary organoid cultures.Curr Protoc Stem Cell BiolKoo, BK., Sasselli, V., Clevers, H.
2012Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.NatureKoo, BK., Spit, M., Jordens, I., Low, TY., Stange, DE., van de Wetering, M., van Es, JH., Mohammed, S., Heck, AJ., Maurice, MM., Clevers, H.
2011Controlled gene expression in primary Lgr5 organoid cultures.Nat MethodsKoo, BK., Stange, DE., Sato, T., Karthaus, W., Farin, HF., Huch, M., van Es, JH., Clevers, H.