2021 | Niche-specific MHC II and PD-L1 regulate CD4+CD8αα+ intraepithelial lymphocyte differentiation. | J Exp Med | Moon, S., Park, Y., Hyeon, S., Kim, YM., Kim, JH., Kim, H., Park, S., Lee, KJ., Koo, BK., Ha, SJ., Lee, SW. |
2021 | Genetic engineering in organoids. | J Mol Med (Berl) | Teriyapirom, I., Batista-Rocha, AS., Koo, BK. |
2021 | Post-translational Wnt receptor regulation: Is the fog slowly clearing? | Bioessays | Tsukiyama, T., Koo, BK., Hatakeyama, S. |
2021 | Wnt/β-catenin signaling: structure, assembly and endocytosis of the signalosome. | Dev Growth Differ | Colozza, G., Koo, BK. |
2021 | Organoids: ready for the revolution? | J Mol Med (Berl) | Koo, BK., Bartfeld, S., Alev, C. |
2020 | Human organoids: model systems for human biology and medicine. | Nat Rev Mol Cell Biol | Kim, J., Koo, BK., Knoblich, JA. |
2020 | Human Microphysiological Models of Intestinal Tissue and Gut Microbiome. | Front Bioeng Biotechnol | Steinway, SN., Saleh, J., Koo, BK., Delacour, D., Kim, DH. |
2020 | Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses. | mBio | Hosmillo, M., Chaudhry, Y., Nayak, K., Sorgeloos, F., Koo, BK., Merenda, A., Lillestol, R., Drumright, L., Zilbauer, M., Goodfellow, I. |
2020 | Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration. | Cell Stem Cell | Choi, J., Park, JE., Tsagkogeorga, G., Yanagita, M., Koo, BK., Han, N., Lee, JH. |
2020 | Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss. | Sci Rep | Morkmued, S., Clauss, F., Schuhbaur, B., Fraulob, V., Mathieu, E., Hemmerlé, J., Clevers, H., Koo, BK., Dollé, P., Bloch-Zupan, A., Niederreither, K. |
2020 | A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis. | Nat Commun | Tsukiyama, T., Zou, J., Kim, J., Ogamino, S., Shino, Y., Masuda, T., Merenda, A., Matsumoto, M., Fujioka, Y., Hirose, T., Terai, S., Takahashi, H., Ishitani, T., Nakayama, KI., Ohba, Y., Koo, BK., Hatakeyama, S. |
2020 | RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer. | EMBO J | Spit, M., Fenderico, N., Jordens, I., Radaszkiewicz, T., Lindeboom, RG., Bugter, JM., Cristobal, A., Ootes, L., van Osch, M., Janssen, E., Boonekamp, KE., Hanakova, K., Potesil, D., Zdrahal, Z., Boj, SF., Medema, JP., Bryja, V., Koo, BK., Vermeulen, M., Maurice, MM. |
2020 | Gastric organoids-an in vitro model system for the study of gastric development and road to personalized medicine. | Cell Death Differ | Seidlitz, T., Koo, BK., Stange, DE. |
2019 | Defining the Identity and Dynamics of Adult Gastric Isthmus Stem Cells. | Cell Stem Cell | Han, S., Fink, J., Jörg, DJ., Lee, E., Yum, MK., Chatzeli, L., Merker, SR., Josserand, M., Trendafilova, T., Andersson-Rolf, A., Dabrowska, C., Kim, H., Naumann, R., Lee, JH., Sasaki, N., Mort, RL., Basak, O., Clevers, H., Stange, DE., Philpott, A., Kim, JK., Simons, BD., Koo, BK. |
2019 | Lineage Tracing: Computational Reconstruction Goes Beyond the Limit of Imaging. | Mol Cells | Wu, SS., Lee, JH., Koo, BK. |
2019 | Human gastric cancer modelling using organoids. | Gut | Seidlitz, T., Merker, SR., Rothe, A., Zakrzewski, F., von Neubeck, C., Grützmann, K., Sommer, U., Schweitzer, C., Schölch, S., Uhlemann, H., Gaebler, AM., Werner, K., Krause, M., Baretton, GB., Welsch, T., Koo, BK., Aust, DE., Klink, B., Weitz, J., Stange, DE. |
2019 | Modeling Host-Virus Interactions in Viral Infectious Diseases Using Stem-Cell-Derived Systems and CRISPR/Cas9 Technology. | Viruses | Kim, J., Koo, BK., Yoon, KJ. |
2019 | Mouse Models of Human Gastric Cancer Subtypes With Stomach-Specific CreERT2-Mediated Pathway Alterations. | Gastroenterology | Seidlitz, T., Chen, YT., Uhlemann, H., Schölch, S., Kochall, S., Merker, SR., Klimova, A., Hennig, A., Schweitzer, C., Pape, K., Baretton, GB., Welsch, T., Aust, DE., Weitz, J., Koo, BK., Stange, DE. |
2019 | DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development. | Gut | Kraiczy, J., Nayak, KM., Howell, KJ., Ross, A., Forbester, J., Salvestrini, C., Mustata, R., Perkins, S., Andersson-Rolf, A., Leenen, E., Liebert, A., Vallier, L., Rosenstiel, PC., Stegle, O., Dougan, G., Heuschkel, R., Koo, BK., Zilbauer, M. |
2019 | A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis. | Genes Dev | Basham, KJ., Rodriguez, S., Turcu, AF., Lerario, AM., Logan, CY., Rysztak, MR., Gomez-Sanchez, CE., Breault, DT., Koo, BK., Clevers, H., Nusse, R., Val, P., Hammer, GD. |