2023 | A cellular hierarchy of Notch and Kras signaling controls cell fate specification in the developing mouse salivary gland. | Dev Cell | Chatzeli, L., Bordeu, I., Han, S., Bisetto, S., Waheed, Z., Koo, BK., Alcolea, MP., Simons, BD. |
2022 | Sensitivity towards HDAC inhibition is associated with RTK/MAPK pathway activation in gastric cancer. | EMBO Mol Med | Seidlitz, T., Schmäche, T., Garcίa, F., Lee, JH., Qin, N., Kochall, S., Fohgrub, J., Pauck, D., Rothe, A., Koo, BK., Weitz, J., Remke, M., Muñoz, J., Stange, DE. |
2022 | Clone wars: From molecules to cell competition in intestinal stem cell homeostasis and disease. | Exp Mol Med | Colozza, G., Park, SY., Koo, BK. |
2022 | Organoid Studies in COVID-19 Research. | Int J Stem Cells | Kim, J., Koo, BK., Clevers, H. |
2022 | Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses. | Adv Sci (Weinh) | Kim, SC., Park, JW., Seo, HY., Kim, M., Park, JH., Kim, GH., Lee, JO., Shin, YK., Bae, JM., Koo, BK., Jeong, SY., Ku, JL. |
2022 | p57Kip2 imposes the reserve stem cell state of gastric chief cells. | Cell Stem Cell | Lee, JH., Kim, S., Han, S., Min, J., Caldwell, B., Bamford, AD., Rocha, ASB., Park, J., Lee, S., Wu, SS., Lee, H., Fink, J., Pilat-Carotta, S., Kim, J., Josserand, M., Szep-Bakonyi, R., An, Y., Ju, YS., Philpott, A., Simons, BD., Stange, DE., Choi, E., Koo, BK., Kim, JK. |
2022 | RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state. | Nat Commun | Belenguer, G., Mastrogiovanni, G., Pacini, C., Hall, Z., Dowbaj, AM., Arnes-Benito, R., Sljukic, A., Prior, N., Kakava, S., Bradshaw, CR., Davies, S., Vacca, M., Saeb-Parsy, K., Koo, BK., Huch, M. |
2022 | A pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression. | Development | Vrij, EJ., Scholte Op Reimer, YS., Fuentes, LR., Guerreiro, IM., Holzmann, V., Aldeguer, JF., Sestini, G., Koo, BK., Kind, J., van Blitterswijk, CA., Rivron, NC. |
2021 | Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration. | Nat Cell Biol | Choi, J., Jang, YJ., Dabrowska, C., Iich, E., Evans, KV., Hall, H., Janes, SM., Simons, BD., Koo, BK., Kim, J., Lee, JH. |
2021 | Methods in organoids: a model that goes beyond our imagination. | Exp Mol Med | Koo, BK. |
2021 | Gastric organoids-an in vitro model system for the study of gastric development and road to personalized medicine. | Cell Death Differ | Seidlitz, T., Koo, BK., Stange, DE. |
2021 | Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway. | EMBO Rep | Colozza, G., Koo, BK. |
2021 | Correction: Gastric organoids-an in vitro model system for the study of gastric development and road to personalized medicine. | Cell Death Differ | Seidlitz, T., Koo, BK., Stange, DE. |
2021 | RNF43/ZNRF3 negatively regulates taste tissue homeostasis and positively regulates dorsal lingual epithelial tissue homeostasis. | Stem Cell Reports | Lu, C., Lin, X., Yamashita, J., Xi, R., Zhou, M., Zhang, YV., Wang, H., Margolskee, RF., Koo, BK., Clevers, H., Matsumoto, I., Jiang, P. |
2021 | Post-translational Wnt receptor regulation: Is the fog slowly clearing?: The molecular mechanism of RNF43/ZNRF3 ubiquitin ligases is not yet fully elucidated and still controversial. | Bioessays | Tsukiyama, T., Koo, BK., Hatakeyama, S. |
2021 | Tracing oncogene-driven remodelling of the intestinal stem cell niche. | Nature | Yum, MK., Han, S., Fink, J., Wu, SS., Dabrowska, C., Trendafilova, T., Mustata, R., Chatzeli, L., Azzarelli, R., Pshenichnaya, I., Lee, E., England, F., Kim, JK., Stange, DE., Philpott, A., Lee, JH., Koo, BK., Simons, BD. |
2021 | Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries. | Proc Natl Acad Sci U S A | Le Rolle, M., Massa, F., Siggers, P., Turchi, L., Loubat, A., Koo, BK., Clevers, H., Greenfield, A., Schedl, A., Chaboissier, MC., Chassot, AA. |
2021 | Genetic engineering in organoids. | J Mol Med (Berl) | Teriyapirom, I., Batista-Rocha, AS., Koo, BK. |
2021 | Organoids: ready for the revolution? | J Mol Med (Berl) | Koo, BK., Bartfeld, S., Alev, C. |
2021 | Niche-specific MHC II and PD-L1 regulate CD4+CD8αα+ intraepithelial lymphocyte differentiation. | J Exp Med | Moon, S., Park, Y., Hyeon, S., Kim, YM., Kim, JH., Kim, H., Park, S., Lee, KJ., Koo, BK., Ha, SJ., Lee, SW. |