List of Publications

2021Niche-specific MHC II and PD-L1 regulate CD4+CD8αα+ intraepithelial lymphocyte differentiation.J Exp MedMoon, S., Park, Y., Hyeon, S., Kim, YM., Kim, JH., Kim, H., Park, S., Lee, KJ., Koo, BK., Ha, SJ., Lee, SW.
2021Wnt/β-catenin signaling: Structure, assembly and endocytosis of the signalosome.Dev Growth DifferColozza, G., Koo, BK.
2021Genetic engineering in organoids.J Mol Med (Berl)Teriyapirom, I., Batista-Rocha, AS., Koo, BK.
2021Correction: Gastric organoids-an in vitro model system for the study of gastric development and road to personalized medicine.Cell Death DifferSeidlitz, T., Koo, BK., Stange, DE.
2021Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration.Nat Cell BiolChoi, J., Jang, YJ., Dabrowska, C., Iich, E., Evans, KV., Hall, H., Janes, SM., Simons, BD., Koo, BK., Kim, J., Lee, JH.
2021SCON - A Short Conditional intrON for conditional knockout with one-step zygote injectionbioRxivWu, S-HS, Szep-Bakonyi R, Lee H, Colozza G, Boese A, Gert KR, Hallay N, Kim J, Zhu Y, Pilat-Carotta S, Theussl H-C, Pauli A, Koo B-K.
2021Methods in organoids: a model that goes beyond our imagination.Exp Mol MedKoo, BK.
2021Tracing oncogene-driven remodelling of the intestinal stem cell niche.NatureYum, MK., Han, S., Fink, J., Wu, SS., Dabrowska, C., Trendafilova, T., Mustata, R., Chatzeli, L., Azzarelli, R., Pshenichnaya, I., Lee, E., England, F., Kim, JK., Stange, DE., Philpott, A., Lee, JH., Koo, BK., Simons, BD.
2021Post-translational Wnt receptor regulation: Is the fog slowly clearing?: The molecular mechanism of RNF43/ZNRF3 ubiquitin ligases is not yet fully elucidated and still controversial.BioessaysTsukiyama, T., Koo, BK., Hatakeyama, S.
2021Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries.Proc Natl Acad Sci U S ALe Rolle, M., Massa, F., Siggers, P., Turchi, L., Loubat, A., Koo, BK., Clevers, H., Greenfield, A., Schedl, A., Chaboissier, MC., Chassot, AA.
2021Organoids: ready for the revolution?J Mol Med (Berl)Koo, BK., Bartfeld, S., Alev, C.
2021Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway.EMBO RepColozza, G., Koo, BK.
2021Gastric organoids-an in vitro model system for the study of gastric development and road to personalized medicine.Cell Death DifferSeidlitz, T., Koo, BK., Stange, DE.
2020Deficiency of the SMOC2 matricellular protein impairs bone healing and produces age-dependent bone loss.Sci RepMorkmued, S., Clauss, F., Schuhbaur, B., Fraulob, V., Mathieu, E., Hemmerlé, J., Clevers, H., Koo, BK., Dollé, P., Bloch-Zupan, A., Niederreither, K.
2020RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.EMBO JSpit, M., Fenderico, N., Jordens, I., Radaszkiewicz, T., Lindeboom, RG., Bugter, JM., Cristobal, A., Ootes, L., van Osch, M., Janssen, E., Boonekamp, KE., Hanakova, K., Potesil, D., Zdrahal, Z., Boj, SF., Medema, JP., Bryja, V., Koo, BK., Vermeulen, M., Maurice, MM.
2020A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.Nat CommunTsukiyama, T., Zou, J., Kim, J., Ogamino, S., Shino, Y., Masuda, T., Merenda, A., Matsumoto, M., Fujioka, Y., Hirose, T., Terai, S., Takahashi, H., Ishitani, T., Nakayama, KI., Ohba, Y., Koo, BK., Hatakeyama, S.
2020Human Microphysiological Models of Intestinal Tissue and Gut Microbiome.Front Bioeng BiotechnolSteinway, SN., Saleh, J., Koo, BK., Delacour, D., Kim, DH.
2020Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration.Cell Stem CellChoi, J., Park, JE., Tsagkogeorga, G., Yanagita, M., Koo, BK., Han, N., Lee, JH.
2020Human organoids: model systems for human biology and medicine.Nat Rev Mol Cell BiolKim, J., Koo, BK., Knoblich, JA.
2020Norovirus Replication in Human Intestinal Epithelial Cells Is Restricted by the Interferon-Induced JAK/STAT Signaling Pathway and RNA Polymerase II-Mediated Transcriptional Responses.mBioHosmillo, M., Chaudhry, Y., Nayak, K., Sorgeloos, F., Koo, BK., Merenda, A., Lillestol, R., Drumright, L., Zilbauer, M., Goodfellow, I.