List of Publications

YearTitleJournalAuthors
2022Organoid Studies in COVID-19 Research.Int J Stem CellsKim, J., Koo, BK., Clevers, H.
2022RNF43/ZNRF3 loss predisposes to hepatocellular-carcinoma by impairing liver regeneration and altering the liver lipid metabolic ground-state.Nat CommunBelenguer, G., Mastrogiovanni, G., Pacini, C., Hall, Z., Dowbaj, AM., Arnes-Benito, R., Sljukic, A., Prior, N., Kakava, S., Bradshaw, CR., Davies, S., Vacca, M., Saeb-Parsy, K., Koo, BK., Huch, M.
2022Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses.Adv Sci (Weinh)Kim, SC., Park, JW., Seo, HY., Kim, M., Park, JH., Kim, GH., Lee, JO., Shin, YK., Bae, JM., Koo, BK., Jeong, SY., Ku, JL.
2022p57Kip2 imposes the reserve stem cell state of gastric chief cells.Cell Stem CellLee, JH., Kim, S., Han, S., Min, J., Caldwell, B., Bamford, AD., Rocha, ASB., Park, J., Lee, S., Wu, SS., Lee, H., Fink, J., Pilat-Carotta, S., Kim, J., Josserand, M., Szep-Bakonyi, R., An, Y., Ju, YS., Philpott, A., Simons, BD., Stange, DE., Choi, E., Koo, BK., Kim, JK.
2022A pendulum of induction between the epiblast and extra-embryonic endoderm supports post-implantation progression.DevelopmentVrij, EJ., Scholte Op Reimer, YS., Fuentes, LR., Guerreiro, IM., Holzmann, V., Aldeguer, JF., Sestini, G., Koo, BK., Kind, J., van Blitterswijk, CA., Rivron, NC.
2022Sensitivity towards HDAC inhibition is associated with RTK/MAPK pathway activation in gastric cancer.EMBO Mol MedSeidlitz, T., Schmäche, T., Garcίa, F., Lee, JH., Qin, N., Kochall, S., Fohgrub, J., Pauck, D., Rothe, A., Koo, BK., Weitz, J., Remke, M., Muñoz, J., Stange, DE.
2022Clone wars: From molecules to cell competition in intestinal stem cell homeostasis and disease.Exp Mol MedColozza, G., Park, SY., Koo, BK.
2021Methods in organoids: a model that goes beyond our imagination.Exp Mol MedKoo, BK.
2021Tracing oncogene-driven remodelling of the intestinal stem cell niche.NatureYum, MK., Han, S., Fink, J., Wu, SS., Dabrowska, C., Trendafilova, T., Mustata, R., Chatzeli, L., Azzarelli, R., Pshenichnaya, I., Lee, E., England, F., Kim, JK., Stange, DE., Philpott, A., Lee, JH., Koo, BK., Simons, BD.
2021Post-translational Wnt receptor regulation: Is the fog slowly clearing?: The molecular mechanism of RNF43/ZNRF3 ubiquitin ligases is not yet fully elucidated and still controversial.BioessaysTsukiyama, T., Koo, BK., Hatakeyama, S.
2021Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries.Proc Natl Acad Sci U S ALe Rolle, M., Massa, F., Siggers, P., Turchi, L., Loubat, A., Koo, BK., Clevers, H., Greenfield, A., Schedl, A., Chaboissier, MC., Chassot, AA.
2021Organoids: ready for the revolution?J Mol Med (Berl)Koo, BK., Bartfeld, S., Alev, C.
2021Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway.EMBO RepColozza, G., Koo, BK.
2021RNF43/ZNRF3 negatively regulates taste tissue homeostasis and positively regulates dorsal lingual epithelial tissue homeostasis.Stem Cell ReportsLu, C., Lin, X., Yamashita, J., Xi, R., Zhou, M., Zhang, YV., Wang, H., Margolskee, RF., Koo, BK., Clevers, H., Matsumoto, I., Jiang, P.
2021Gastric organoids-an in vitro model system for the study of gastric development and road to personalized medicine.Cell Death DifferSeidlitz, T., Koo, BK., Stange, DE.
2021Wnt/β-catenin signaling: Structure, assembly and endocytosis of the signalosome.Dev Growth DifferColozza, G., Koo, BK.
2021Genetic engineering in organoids.J Mol Med (Berl)Teriyapirom, I., Batista-Rocha, AS., Koo, BK.
2021Niche-specific MHC II and PD-L1 regulate CD4+CD8αα+ intraepithelial lymphocyte differentiation.J Exp MedMoon, S., Park, Y., Hyeon, S., Kim, YM., Kim, JH., Kim, H., Park, S., Lee, KJ., Koo, BK., Ha, SJ., Lee, SW.
2021Correction: Gastric organoids-an in vitro model system for the study of gastric development and road to personalized medicine.Cell Death DifferSeidlitz, T., Koo, BK., Stange, DE.
2021Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration.Nat Cell BiolChoi, J., Jang, YJ., Dabrowska, C., Iich, E., Evans, KV., Hall, H., Janes, SM., Simons, BD., Koo, BK., Kim, J., Lee, JH.