Youssef Belkhadir


Chaube MA, Trattnig N, Lee DH, et al. (2022) Synthesis of Fungal Cell Wall Oligosaccharides and Their Ability to Trigger Plant Immune Responses. Euopean J Org Chem 2022(27):e202200313.

Clasen SJ, Bell ME, Lee D, et al. (2022) Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5. bioRxiv:2022.04.12.488020.

Stegmann M, Zecua-Ramirez P, Ludwig C, et al. (2022) RGI-GOLVEN signaling promotes cell surface immune receptor abundance to regulate plant immunity. EMBO Rep 23(5):e53281 preprint bioRxiv:2021.01.29.428839..


Colaianni NR, Parys K, Lee HS, et al. (2021) A complex immune response to flagellin epitope variation in commensal communities. Cell Host Microbe 29(4):635-49.

Doumane M, Lebecq A, Colin L, et al. (2021) Inducible depletion of PI(4,5)P2 by the synthetic iDePP system in Arabidopsis. Nat Plants 7(5):587-97.

Lee DH, Lee HS, Belkhadir Y (2021) Coding of plant immune signals by surface receptors. Curr Opin Plant Biol 62:102044.

Lee HS, Choi I, Jeon Y, et al. (2021) Chaperone-like protein DAY plays critical roles in photomorphogenesis. Nat Commun 12(1):4194.

Parys K, Colaianni NR, ..., Belkhadir Y (2021) Signatures of antagonistic pleiotropy in a bacterial flagellin epitope. Cell Host Microbe 29(4):620-34.

Wolinska KW, Vannier N, Thiergart T, et al. (2021) Tryptophan metabolism and bacterial commensals prevent fungal dysbiosis in Arabidopsis roots. Proc Natl Acad Sci USA 118(49):e2111521118.


Hajný J, Prát T, Rydza N, et al. (2020) Receptor kinase module targets PIN-dependent auxin transport during canalization. Science 370(6516):550-7.

Lee HS and Belkhadir Y (2020) Damage Control: Cellular Logic in the Root Immune Response. Cell Host Microbe 27(3):308-10.


Kutschera A, Dawid C, Gisch N, et al. (2019) Bacterial medium chain 3-hydroxy fatty acid metabolites trigger immunity in Arabidopsis plants. Science 364(6436):178-81.

Luu DD, Joe A, Chen Y, et al. (2019) Biosynthesis and secretion of the microbial sulfated peptide RaxX and binding to the rice XA21 immune receptor. Proc Natl Acad Sci USA 116(17):8525-34.

Mott GA, Smakowska-Luzan E, Pasha A, et al. (2019) Map of physical interactions between extracellular domains of Arabidopsis leucine-rich repeat receptor kinases. Sci Data 6:190025.

Xiao Y, Stegmann M, Han Z, et al. (2019) Mechanisms of RALF peptide perception by a heterotypic receptor complex. Nature 572(7768):270-4.


Ahmed H, Howton TC, Sun Y, Weinberger N, Beklhadir Y, Mukhtar MS (2018) Network biology discovers pathogen contact points in host protein-protein interactomes. Nat Commun 9(1):2312.

Smakowska-Luzan E, G. Adam Mott, ..., Belkhadir Y (2018) An extracellular network of Arabidopsis leucine-rich repeat receptor kinases. Nature 553(7688):342-6.

Doblas VG, Smakowska-Luzan E, Fujita S, et al. (2017) Root diffusion barrier control by a vasculature-derived peptide binding to the SGN3 receptor. Science 355(6322):280-4.

Lozano-Duran R and Belkhadir Y. (2017) A technical framework for studying the signaling nexus of brassinosteroids and immunity. Methods Mol Biol 1564:49-61

Stegmann M, Monaghan J, Smakowska-Luzan E, et al. (2017) The receptor kinase FER is a RALF-regulated scaffold controlling plant immune signaling. Science 355(6322):287-9.

Elsayad K, Werner S,...,Belkhadir Y (2016) Mapping the subcellular mechanical properties of live cells in tissues with fluorescence emission-Brillouin imaging. Sci Signal 9(435):rs5.

Mott GA, Thakur S, Smakowska E, et al. (2016) Genomic screens identify a new phytobacterial microbe-associated molecular pattern and the cognate Arabidopsis receptor-like kinase that mediates its immune elicitation. Genome Biol 17:98.

Saur IM, Kadota Y, Sklenar J, et al. (2016) NbCSPR underlies age-dependent immune responses to bacterial cold shock protein in Nicotiana benthamiana. Proc Natl Acad Sci USA 113(12):3389-94.

Smakowska E, Kong J, Busch W, Belkhadir Y (2016) Organ-specific regulation of growth-defense tradeoffs by plants. Curr Opin Plant Biol 29:129-137.

Belkhadir Y, Jaillais Y (2015) The molecular circuitry of brassinosteroid signaling. New Phytol 206(2):522-40.

Belkhadir Y, Yang L, Hetzel J, et al. (2014) The growth–defense pivot: crisis management in plants mediated by LRR-RK surface receptors. Trends Biochem Sci 39(10):447-56.

Belkhadir Y, Jaillais Y, Epple P, et al. (2012). Brassinosteroid modulate the efficiency of the plant immune system. Proc Natl Acad USA 109(1): 297-302. 

Hothorn M, Belkhadir Y, Dreux M, et al. (2011). Structural basis of steroid hormone perception by the receptor kinase BRI1. Nature 474(7352): 467-71.

Jaillais Y, Belkhadir Y, Balsemão-Pires E, et al. (2011) Extracellular leucine rich repeats as a platform for receptor/coreceptor complex formation. Proc Natl Acad Sci 108(20): 8503-7

Jaillais Y, Hothorn M, Belkhadir Y, et al. (2011) Tyrosine phosphorylation regulates Brassinosteroid signaling at the plasma membrane. Genes Dev 25(3): 232-7.

Belkhadir Y, Wierzba M, Durbak A, et al. (2010) Intragenic suppression of a trafficking defective Brassinoteroid receptor in Arabidopsis. Genetics 185(4): 1283-96

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