Frederic Berger


Berger F (2019) Emil Heitz, a true epigenetics pioneer. Nat Rev Mol Cell Biol [epub].

Berger F. An ancient antisense-driven RNA switch drives plant sex determination. EMBO J [epub].

Borg M, Buendía D, Berger F (2019) A simple and robust protocol for immunostaining Arabidopsis pollen nuclei. Plant Reprod 32(1):39-43.

Hisanaga T, Yamaoka S, Kawashima T, et al. (2019) Building new insights in plant gametogenesis from an evolutionary perspective. Nat Plants 5:663-9.

Nie WF, Lei M, Zhang M, et al. (2019) Histone acetylation recruits the SWR1 complex to regulate active DNA demethylation in Arabidopsis. Proc Natl Acad Sic USA [epub].


Higo A, Kawashima T, Borg M et al. (2018) Transcription factor DUO1 generated by neo-functionalization is associated with evolution of sperm differentiation in plants. Nat Commun 9:5283.

Lim TK, Ma Y, Berger F, et al. (2018) Acupuncture and Neural Mechanism in the Management of Low Back Pain-An Update. Medicines (Basel) 5(3):E63.

Osakabe A, Lorkovic ZJ, Kobayashi W, et al. (2018) Histone H2A variants confer specific properties to nucleosomes and impact on chromatin accessibility. Nucleic Acids Res 46(15):7675-85.

Ueda M and Berger F (2018) New cues for body axis formation in plant embryos. Curr Opin Plant Biol 47:16-21

Wang H, Jiang D, Axelsson E, et al. (2018) LHP1 interacts with ATRX through plant-specific domains at specific loci targeted by PRC2. Mol Plant 11(8):1038-52.


Bowman JL, Kohchi T, Yamato KT et al. (2017) Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome. Cell 171(2):287-304.

Ingouff M, Selles B, Michaud C, et al. (2017) Live-cell analysis of DNA methylation during sexual reproduction in Arabidopsis reveals context and sex-specific dynamics controlled by noncanonical RdDM. Genes Dev 31(1):72-83.

Jiang D and Berger F (2017) DNA replication-coupled histone modification maintains Polycomb gene silencing in plants. Science 357(6356):1146-9.

Lorković Z, Park C, Goiser M, et al. (2017) Compartmentalization of DNA Damage Response between Heterochromatin and Euchromatin Is Mediated by Distinct H2A Histone Variants. Curr Biol 27(8):1192-9.

Lorković ZJ, Berger F (2017) Heterochromatin and DNA damage repair: use different histone variants and relax. Nucleus [epub].

Motomura K, Kawashima T, Berger F et al. (2017) A pharmacological study of Arabidopsis cell fusion between the persistent synergid and endosperm. J Cell Sci [epub].

Susaki D, Maruyama D, Yelagandula R, et al. (2017) Live-Cell Imaging of F-Actin Dynamics During Fertilization in Arabidopsis thaliana. Methods Mol Biol 1668:47-54.

Wollmann H, Stroud H, Yelagandula R, et al. (2017) The histone H3 variant H3.3 regulates gene body DNA methylation in Arabidopsis thaliana. Genome Biol 18(1):94.

Yelagandula R, Osakabe A, Axelsson E, et al. (2017) Genome-Wide Profiling of Histone Modifications and Histone Variants in Arabidopsis thaliana and Marchantia polymorpha. Methods Mol Biol. 1610:93-106.


Berger F, Bowman JL, Kohchi T (2016) Marchantia. Curr Biol 26(5):R186-7.

Berger F, Geyer PK (2016) Editorial overview: Genome architecture and expression: Connecting genome composition and nuclear architecture with function. Curr Opin Genet Dev 37:iv-vi.

Jiang D, Berger F (2016) Histone variants in plant transcriptional regulation. Biochim Biophys Acta 1860(1):123-30.

Kimata Y, Higaki T, Kawashima T, et al. (2016) Cytoskeleton dynamics control the first asymmetric cell division in Arabidopsis zygote. Proc Natl Acad Sci USA 113(49):14157-62.

Motomura K, Berger F, Kawashima T, et al (2016) Fertilization-independent cell-fusion between the synergid and central cell in the polycomb mutant. Cell Struct Funct 41(2):121-5.


Borg M, Berger F (2015) Chromatin remodelling during male gametophyte development.  Plant J 83(1):177-88.

Bowman JL, Araki T, Arteaga-Vazquez MA, et al. (2015) The naming of names: guidelines for gene nomenclature in Marchantia. Plant Cell Physiol 57(2):257-61.

Kawashima T, Berger F (2015) The central cell nuclear position at the micropylar end is maintained by the balance of F-actin dynamics, but dispensable for karyogamy in Arabidopsis. Plant Reprod 28(2):103-10.

Kawashima T, Lorkovic ZJ, Nishihama R, et al. (2015) Diversification of histone H2A variants during plant evolution. Trends Plant Sci 20(7):419-25.

Roscoe T, Guilleminot J, Bessoule JJ, et al. (2015) Complementation of Seed Maturation Phenotypes by Ectopic Expression of ABSCISSIC ACID INSENSITIVE3, FUSCA3 and LEAFY COTYLEDON2 in Arabidopsis. Plant Cell Physiol 56(6):1215-28.


Kawashima T, Berger F (2014) Epigenetic reprogramming in plant sexual reproduction. Nat. Rev. Genet. 15(9):613-24.

Nie X, Wang H, Li J, Holec S, Berger F (2014) The HIRA complex that deposits the histone H3.3 is conserved in Arabidopsis and facilitates transcriptional dynamics. Biol Open 3(9):794-802.

Mori T., Igawa T., Tamiya G., Miyagishima S. and Berger F (2014) Gamete Attachment Requires GEX2 for Successful Fertilization in Arabidopsis. Current Biology 24, 170-175.

Kawashima T, Maruyama D, Shagirov M, Li J, Hamamura Y, Yelagandula R, Toyama Y, Berger F (2014) Dynamic F-actin movement is essential for fertilization in Arabidopsis thaliana. eLife 2014;3:e04501.

Yelagandula R, Stroud H, Holec S, et al. (2014) The histone variant H2A.W defines heterochromatin and promotes chromatin condensation in Arabidopsis. Cell 158(1):98-109.


Li J, Nie X, Tan JL, Berger F. (2013) Integration of epigenetic and genetic controls of seed size by cytokinin in Arabidopsis. Proc Natl Acad Sci U S A. 110:15479-84.


Vu TM, Nakamura M, Calarco JP, Susaki D, Lim PQ, Kinoshita T, Higashiyama T, Martienssen RA, Berger F. (2012) RNA-directed DNA methylation regulates parental genomic imprinting at several loci in Arabidopsis. Development. 140:2953-60.

Calarco JP, Borges F, Donoghue MT, Van Ex F, Jullien PE, Lopes T, Gardner R, Berger F, Feijó JA, Becker JD, Martienssen RA. (2012) Reprogramming of DNA Methylation in Pollen Guides Epigenetic Inheritance via Small RNA. Cell 151 :194-205.

Jullien PJ, Susaki D, Yelagandula R, Higashiyama T, and Berger F (2012) DNA methylation dynamics during sexual reproduction in Arabidopsis thaliana. Curr Biol 22: 1825-1830.

Wollmann H, Holec S, Alden K, Clarke ND, Jacques P-E, Berger F (2012). Dynamic Deposition of Histone Variant H3.3 Accompanies Developmental Remodeling of the Arabidopsis Transcriptome. Plos Genetics, 10.1371/journal.pgen.1002658.


Hamamura Y, Saito C, Awai C, Kurihara D, Miyawaki A, Nakagawa T, Kanaoka M, Sasaki N, Nakano A, Berger F, and Higashiyama T. (2011) Live-Cell Imaging Reveals the Dynamics of Two Sperm Cells during Double Fertilization in Arabidopsis thaliana. Curr Biol, 21: 497-502.

Chen Z, Higgins JD, Tan Li Hui J, Li J, Franklin FCH and Berger F (2011). Retinoblastoma protein is essential for early meiotic events in Arabidopsis EMBO J. 30: 744-755.


Ingouff M, Rademacher S, Holec S, Šoljić L, Nie Xin, Readshaw A, Foo SH, Lahouze B, Sprunck S, Berger F (2010) Zygotic Resetting of the HISTONE 3 Variant Repertoire Participates in Epigenetic Reprogramming in Arabidopsis. Curr Biol 20: 2137-2143.

Wang, A, Garcia, D, Zhang, H, Feng, K, Chaudhury, A, Berger, F, Peacock, JW, Dennis, ES and Luo, M (2010). The VQ motif protein IKU1 controls endosperm growth and seed size in Arabidopsis. Plant J. 63: 670–679.

Aw, S.J, Hamamura, Y, Chen, Y, Schnittger, A and Berger F (2010) Sperm entry is sufficient to trigger division of the central cell but the paternal genome is required for endosperm development in Arabidopsis. Development, 137: 2683-2690.

Jullien, P. and Berger, F (2010) Parental dosage imbalance deregulates imprinting in Arabidopsis. Plos Genet 6: e1000885.

Andreuzza S,  Li J, Guitton A-E, Faure JF, Casanova S, Park J, Choi Y, Chen Z and Berger F (2010) DNA LIGASE I exerts a maternal effect on seed development in Arabidopsis thaliana. Development 137:73-81.


Fitz Gerald JN, Hui PS, Berger F. (2009) Polycomb group-dependent imprinting of the actin regulator AtFH5 regulates morphogenesis in Arabidopsis thaliana. Development 136:3399-404.

Chen Z, Hafidh S, Poh SH ,Twell D and Berger F. (2009) Proliferation and cell fate establishment during Arabidopsis male gametogenesis depends on Retinoblastoma. PNAS 106:7257-7262.

Ingouff, M, Sakata, T, Li, J, Sprunck, S, Dresselhaus, T, and Berger, F. (2009). The two male gametes share equal ability to fertilize the egg cell in Arabidopsis thaliana. Curr Biol, 19: R19-20.


Capron, A, Gourgues, M, Neiva, L S, Faure J-E, Berger, F, Pagnussat G, Anjali Krishnan, A, Alvarez-Mejiam C, Vielle-Calzada J-P, Lee, Y, Liu, B, and Sundaresan V (2008). Maternal Control of Male-Gamete Delivery in Arabidopsis Involves a Putative GPI-Anchored Protein Encoded by the LORELEI Gene. Plant Cell 20: 3038-3049.

Jullien, P.E., Mosquna, A., Ingouff, M., Sakata T., Ohad, N. and Berger, F. (2008) Retinoblastoma and its Binding Partner MSI1 Control Imprinting in Arabidopsis. Plos Biology 6: e94.

Chen, Z, Tan Li Hui J, Ingouff M, Sundaresan V, Berger F (2008) The Chromatin Assembly Factor 1 regulates the cell cycle but not the cell fate during male gametogenesis in Arabidopsis thaliana. Development 135 : 65-73.

Rotman N, Gourgues M, Guitton A-E, Faure J-E and Berger, F. (2008). A dialogue between the sirène pathway in synergids and the fertilization independent seed pathway in the central cell controls male gamete release during double fertilization in Arabidopsis. Molecular Plant doi: 10.1093/mp/ssn023

FitzGerald J, Luo, M, Chaudhury A and Berger F. (2008) DNA Methylation Causes Predominant Maternal Controls of Plant Embryo Growth. Plos One 3(5): e2298. doi:10.1371/journal.pone.0002298.


Ingouff M, Hamamura Y, Gourgues M, Higashiyama T, Berger F (2007) Distinct dynamics of HISTONE3 variants between the two fertilization products in plants. Cur Biol 17: 1032-1037.


Ingouff M, Jullien, PE, Berger F (2006) The female gametophyte and the endosperm control cell proliferation and differentiation of the seed coat in Arabidopsis. Plant Cell 18 : 3491-501.

Jullien P, Kinoshita T, Ohad N, Berger F (2006) Maintenance of DNA Methylation During the Arabidopsis Life Cycle is Essential for Parental Imprinting. Plant Cell 18:1360-1372.

Jullien P, Katz A, Oliva M, Ohad, N, Berger F (2006) Polycomb group complexes self-regulate imprinting of the Polycomb group gene MEDEA in Arabidopsis. Curr. Biol. 16: 486-494.


Luo M, Dennis ES, Berger F, Peacock J, Chaudhury A (2005) MINISEED3 (MINI3), a WRKY family gene, and IKU2, a LRR KINASE gene, are regulators of endosperm development and seed size in Arabidopsis. Proc Natl Acad Sci USA. 29:17531-17536.

Guitton A-E, Berger F (2005) Loss-of-function of MULTICOPYSUPPRESSOR OF IRA 1 produces non-viable parthenogenetic embryos in Arabidopsis. Curr. Biol. 15: 750-754.

Ingouff M, Haseloff J, Berger F (2005) Polycomb group genes control developmental timing of endosperm. Plant J. 42 : 663-674.

Ingouff M, FitzGerald JN, Guérin C, Robert N, Sørensen M, Van Damme D, Geelen D, Blanchoin L, Berger F  (2005) Plant formin AtFH5 is an evolutionarily conserved actin nucleator involved in cytokinesis. Nat. Cell Biol. 7 :374-380.

Rotman N, Durbarry A, Wardle A, Yang WC, Chaboud A, Faure J-E, Berger F, Twell D (2005) A Novel Class of MYB factors control sperm-cell formation in plants. Cur. Biol. 15, 244-248.

Garcia D, FitzGerald JN, Berger F (2005) Maternal control of integument cell elongation and zygotic control of endosperm growth are coordinated to determine seed size in arabidopsis. Plant Cell 17: 52-60.


Vespa L, Vachon, G, Berger F, Perazza D, Faure J-D, Herzog M (2004) The immunophilin-interacting protein AtFIP37 is essential for plant development and is involved in trichome endoreduplication. Plant Physiol. 134: 1283-1292.

Guitton A-E, Page D, Chambrier P, Lionnet C, Jean-Emmanuel Faure J-E, Grossniklaus U, Berger F (2004) Identification of new members of Fertilisation Independent Seed Polycomb Group pathway involved in the control of seed development in Arabidopsis thaliana. Development 131: 2971-2981.


Rotman N, Rozier F, Boavida L, Dumas C, Berger F, Faure JE (2003). Female control of male gamete delivery during fertilization in Arabidopsis thaliana. Curr. Biol. 13: 432-436.

Garcia D, Saingery V, Chambrier P, Mayer U, Jürgens G, Berger F (2003) Arabidopsis haiku mutants reveal new controls of seed size by endosperm. Plant Physiol. 131: 1661-1670.


Sørensen, MB, Mayer U, Lukowitz W, Robert H, Chambrier P, Jürgens G, Somerville C, Lepiniec L, Berger F (2002) Cellularisation in the endosperm of Arabidopsis thaliana is coupled to mitosis and shares multiple components with cytokinesis. Development, 129: 5567-5576.

Despres B, Bouissonnie F, Wu HJ, Gomord V, Guilleminot J, Grellet F, Berger F, Delseny M, Devic M (2003) Three SAC1-like genes show overlapping patterns of expression in Arabidopsis but are remarkably silent during embryo development. Plant J. 34: 293-306.

Menand B, Desnos T, Nussaume L, Berger F, Bouchez D, Meyer C, Robaglia C (2002) Expression and disruption of the Arabidopsis TOR (target of rapamycin) gene. Proc Natl Acad Sci USA 99: 6422-6427.