List of Publications, PD Dr. Myrtill SIMKO

as of December 2007


Original Papers (peer-reviewed)

Simkó M: Cell type specific redox status is responsible for diverse electromagnetic field effects, Curr. Med. Chem. 14, 1141-1152, (invited review) (2007)

Frahm J, Lantow M, Lupke M, Weiss DG and Simkó M: Alteration in cellular functions in mouse macrophages after exposure to 50 Hz magnetic fields J. Cell. Biochem. 99, 168-77 (2006)

Lantow M, Lupke M, Frahm J, Mattsson MO, Kuster N, and Simkó M: ROS release and Hsp70 expression after exposure to 1800 MHz radiofrequency electromagnetic fields in primary human monocytes and lymphocytes Radiat. Environ. Biophys. 45, 55-62 (2006)

Lantow M, Viergutz T and Simkó M: Cell cycle analysis and apoptosis induction after exposure to radiofrequency radiation in human Mono Mac 6 cells, Radiat Res. 166, 539-43 (2006)

Lupke M, Frahm J, Lantow M, Maercker C, Remondini D, Bersani F and Simkó M: Gene expression analysis of ELF-MF exposed human monocytes indicating the involvement of the alternative activation pathway, Biochim. Biophys. Acta. 1763, 4, 402-412 (2006)

Lantow M, Schuderer J, Hartwig C and Simkó M: Free radical release and Hsp70 expression in two human immune relevant cell lines after exposure to 1800 MHz radiofrequency radiation Radiat. Res. 165, 88-94 (2006)

Simkó M, Hartwig C, Lantow M, Lupke M, Mattsson MO, Rahman Q and Rollwitz J: Hsp70 expression and free radical release after exposure to non-thermal radio-frequency electromagnetic fields and ultrafine particles in human Mono Mac 6 cells, Toxicol. Lett. 161, 73-82 (2006)

Lohrke B, Viergutz T, Kanitz W, Losand B, Weiss DG, Simkó M: Hydroperoxides in circulating lipids from dairy cows: Implications for bioactivity of endogenous-oxidized lipids, J. Dairy Science, 88, 1708-1710 (2005)

Simkó M: Induction of cell activation processes by low frequency electromagnetic fields. The Scientific World 4, 4–22, (2004)

Simkó M. and Mattsson MO: Extremely low frequency electromagnetic fields as effectors of cellular responses in vitro: possible immune cell activation. J Cell Biochem. 1;93(1):83-92 (2004)

Kriehuber R, Riedling M, Simko M, Weiss DG.:Cytotoxicity, genotoxicity and intracellular distribution of the Auger electron emitter (65)Zn in two human cell lines.Radiat Environ Biophys. 43(1):15-22. (2004)

Lange S., D. Richard T. Viergutz R. Kriehuber and M. Simkó: Alterations in the cell cycle and in the protein level of cyclin D1, p21CIP1, and p16INK4a after exposure to 50 Hz MF in human cells. Radiat. Envion. Biophys. 41, 131-137 (2002)

Richard D, Lange S., Viergutz T., Kriehuber R., Weiss D.G., Simkó M.: Influence of 50 Hz magnetic fields in combination with a tumour promoting phorbol ester on protein kinase C and cell cycle in human cells. Mol. Cell. Biochem. 232, 133-141 (2002)

Simkó M., Droste S., Kriehuber R. and Weiss D.G.: Stimulation of phagocytosis and free radical production in murine macrophages by 50 Hz electromagnetic fields. Eur. J. Cell Biol. 80, 562-566 (2001a)

Simkó M, D. Richard, R. Kriehuber and Dieter G. Weiss: Micronucleus induction in SHE cells following exposure to 50 Hz magnetic fields, Benzo(a)pyrene and TPA in vitro. Mutat. Res. 495, 43-50 (2001b)

Kriehuber R and Simkó M.: Apoptosis induction and micronucleus formation after exposure to the auger-electron emitter zinc-65 in a human cell line. Acta Oncologica, 39, 699-706 (2000)

Simkó M., E. Dopp and R. Kriehuber: Absence of synergistic effects on micronucleus formation after exposure to ELF-EMF and asbestos fibers in vitro. Toxic. Lett., 108, 47-53 (1999)

Kriehuber R., Simkó M., Schiffmann D. and Trott K.R.: Delayed cytotoxic and genotoxic effects in a human cell line following X-irradiation. Int. J. Radiat. Biol. 75, 1021-1027 (1999)

Simkó M., R. Kriehuber, S. Lange: Micronucleus formation in human amnion cells after exposure to 50 Hz MF applied horizontally and vertically. Mutat. Res., 418, 101-111 (1998 b)

Simkó M., Kriehuber R., Weiss D.G. and Luben R.:The effects of 50 Hz EMF exposure on micronucleus formation and apoptosis in transformed and non transformed human cell lines. Bioelectromagnetics, 19, 85-91 (1998 a)

Simkó M., Noßke D.: Basis for a revision of the gastrointestinal tract model. Radiation Protection Dosimetry 63, 29-36 (1996)

Dopp E., Nebe B., Hahnel C., Papp T., Alonso B., Simkó M. and Schiffmann, D.: Mineral fibers induce apoptosis in syrian hamster embryo (SHE) fibroblasts. Pathobiology 63, 213-221 (1995)

Simkó M., Noßke D.: Grundlagen zur Revision des biokinetischen Magen-Darm-Trakt-Modells. BfS / ISH - Berichte, ISH-IB 5, 1-35 (1995)

Lux D., Kammerer L., Simkó M., Hiersche L., Wirth E.: Migration und Transfer von Transuranen (Pu, Am) und langlebigen Spaltprodukten (Sr, Ru, Sb, Cs, Eu) in Waldökosystemen der 30-km Zone von Tschernobyl. In: Umweltradioaktivität, Radioökologie, Strahlenwirkungen; Hrsg., Winter M., Wicke A.; Verlag TÜV Rheinland, Köln, Band 2, 715-720 (1993)

Hadjiolov N., Simkó M., Zimmermann H.P.: Immunohistochemical demonstration of rat pancreatic cancer-related antigen by monoclonal antibodies. Compt. Rend. de L'Academie bulgare des Sciences 42, N 6, 325-327 (1989)


Books, Proceedings, Monographs, etc.

International Commission on Radiological Protection (ICRP): Human alimentary tract model for radiological protection. ICRP Publication 100. A report of The International Commission on Radiological Protection. Ed. J. Valentin, Ann ICRP. 2007, 36, 25-327, (2006)

Simkó M: Synergistic effects after exposure to NF-EMF and other noxes. In: FGF-Workshop of Genetic and cytogenetic aspects of RF-field interaction. Herg. Berufsgenossenschaft der Feinmechanik und Elektrotechnik, pp 35-37 (2005)

Gminski R, Schlatterer K, Fitzner RG, Simkó M: Genotoxische Effekte durch hochfrequente elektromagnetische Felder. In: Risikobewertung Mobilfunk; Ergebnisse eines wissenschaftlichen Dialogs. Eds. PM Wiedemann, H. Schutz, A. Spangenberg. Forschungszentrum Julich, Umwelt/Envionment, 54, A1-31 (2005)

Simkó M: Cells meet electromagnetic fields – Biologische Wirksamkeit elektromagnetischer Felder, Traditio et Innovatio, Das Forschungsmagazin der Universität Rostock, Heft 2, 8. Jahrgang, 30-33 (2003)

Simkó M: Synergistic effects after exposure to NF-EMF and other noxes. Workshop of “Genetic and cytogenetic aspects of RF-field interaction” Löwenstein , Germany Proceedings, 48-52 (2002)

Simkó M: Zellulärer Wirkmechanismen zur Wirkung elektromagnetischer Felder. In: Fachgespräch: Forschungsprojekte zur Wirkung elektromagnetischer Felder des Mobilfunks, Bundesamt für Strahlenschutz, Eds. J. Brix, R. Matthes, O. Schulz, W. Weiß, BfS Schriften 25/2002, 72-73 (2002)

Simkó M: Electromagnetic fields as effector for cellular responses in vitro. In: COST 244 BIS Biomedical Effects of Electromagnetic Fields; Workshop “Biological EMF-Interaction Mechanisms and their relevance to exposure Limits, 2000 Munich, Germany; Proceedings, 73-79 (2000)

Simkó M, Kriehuber R, Noßke D: Revision of the biokinetic data of Cobalt. International Commission on Radiological Protection (ICRP), Committee 2; Oak Ridge/Tennesse, USA 1998; ICRP-C2/HAT/98-15, 1-29 (1998)

Kriehuber R, Simkó M: Target cell dosimetry for short-range particles: The biological effects of the Auger Emitter 65Zn. Radiation Fields, Dosimetry, Biokinetics and Biophysical Models for Cancer Induction by Ionising Radiation 1996-1999, Ed. J. Ertel, GSF Forschungszentrum für Umwelt und Gesundheit GmbH, Neuherberg, 49-59, (1998)

Simkó M, Noßke D: Ein neues biokinetisches Modell für den Magen-Darm-Trakt. In: BfS Jahresbericht 1994, Bundesamt für Strahlenschutz, Salzgitter, 83-85, (1995)

Simkó M, Noßke D: Grundlagen zur Revision des biokinetischen Magen-Darm-Trakt-Modells. BfS / ISH-IB 5, 1-35 (1995)

Simkó M: A new gastrointestinal-tract-model. International Commission on Radiological Protection (ICRP), Committee 2; Cadarache, France 1994; ICRP/94/C 2-12 (1994)

Kriehuber R, Dehos A, Simkó M, Meier S: Molekularbiologische Untersuchungen zur Wirkung ionisierender Strahlung. In: BfS Jahresbericht 1992, Bundesamt für Strahlenschutz, Salzgitter, 64-67, (1993)

Kammerer L, Hiersche L, Lux D, Simkó M, Wirth E: Verhalten von Radionukliden in Böden und Pflanzen innerhalb der 30-km Zone von Chernobyl. In: BfS Jahresbericht 1992, Bundesamt für Strahlenschutz, Salzgitter, 76-77, (1993)

Lux D, Kammerer L, Simkó M, Hiersche L, Wirth E: Migration und Transfer von Transuranen (Pu, Am) und langlebigen Spaltprodukten (Sr, Ru, Sb, Cs, Eu) in Waldökosystemen der 30-km Zone von Tschernobyl. In: Umweltradioaktivität, Radioökologie, Strahlenwirkungen; Hrsg., Winter M., Wicke A.; Verlag TÜV Rheinland, Köln, Band 2, 715-720 (1993)


Invited Lectures

Induction of cell activation processes by MFs: cell activation via the alternative pathway in immune relevant cells. Stockholm University, 19. April 2007, Stockholm, Sweden

Induction of cell activation processes by low frequency electromagnetic fields. University Vienna, 15 December 2006, Vienna, Austria

ELF-MF induce cell activation via the alternative pathway in immune relevant cells. Plenary lecture at the 4th International Workshop on Biological Effects of Electromagnetic Fields. 16-20 October 2006, Crete, Greece.

Functional and molecular investigations after 1.8 GHz radiofrequency electromagnetic fields exposure in different immune cells. Workshop "Proposed mechanisms for the interaction of RF-Signals with living Matter", 11-13th September 2006, Rostock, Germany.

DNA repair. Örebro University, 6th December 2005, Örebro, Sweden.

Genotoxic effects after exposure to ELF-EMF and other noxes, Erice School, 2005 Italy.

Induction of cell activation processes by low frequency electromagnetic fields. 27 Annual Meeting of The BEMS, 2005, Dublin, Ireland.

Biological effectiveness of electromagnetic fields. University of Wageningen, 17th January 2005, Wageningen, Holland.

Cells and EMF - Biological effectiveness of electromagnetic fields. Annual Winter-Meeting of The Bioelectromagnetics Society, 5th February 2005, Phoenix, Arizona, USA

Cells meet electromagnetic fields. Örebro University, 16th December 2004, Örebro, Sweden.

Mechanisms of cell activation processes after exposure to electromagnetic fields. 6th International Congress of the European Bioelectromagnetics Association (EBEA), 13–15 November 2003 Budapest, Hungary.

Cell activation processes induced by 50 Hz electromagnetic fields. 25 Annual Meeting of The BEMS, 2003, Maui, Hawaii, USA.

Cell cycle disturbances, interleukin production and generation of super oxide radicals after exposure to 50 Hz EMF in mouse macrophages. 24 Annual Meeting of The BEMS, 2002, Quebec, Canada.

Synergistic effects after exposure to NF-EMF and other noxes. Workshop of “Genetic and cytogenetic aspects of RF-field interaction” Löwenstein (Stuttgart), Germany 24th - 27th November 2002, Löwenstein.

Biologische Wirkungen von elektromagnetischen Feldern. Diskussionsforum der Stadt Rostock (Umweltsenator, T-Mobil), 29.10.2002 Rostock.

How electromagnetic fields act in biologic systems? Prof. Adlkofer, Reflex-Meeting 25.10.-17.10.2002 Bologna, Italien.

Elektrosmog? III. Umweltmedizinisches Symposium der Ärztekammer Mecklenburg Vorpommern, Rostock (Prof. Hennighausen) 24. November 2001, Rostock.

Biologische Wirkungen von elektromagnetischen Feldern. Diskussionsseminar Elektrosmog, Vorkommen-Wirkungen-Messen. Technologiepark Warnemünde (Prof. J. Kreutzmann) 26. Oktober 2001, Warnemünde.

Micronucleus induction in SHE cells following exposure to 50 Hz magnetic fields, Benzo(a)pyrene and TPA in vitro. 23 Annual Meeting of The BEMS, 2001, St. Paul, Minnesota, USA, 2001, St. Paul, USA.

Sind elektromagnetische Felder Streßfaktoren oder mögliche Stimuli für Zellaktivierung? Seminarreihe im Institut für Zoologie (Prof. Herwig O. Gutzeit), Technische Universität Dresden, 29.05.2001, Dresden.

EMF as possible stimuli for cell activation? Kleinheubacher Tagung 2000 des "International Union of Radio Science" (U.R.S.I.) Landesausschusses in der Bundesrepublik Deutschland, 26.09. 2000, Kleinheubach.

Biological effectiveness of electromagnetic fields. Frederic Joliot-Curie National Research Institute for Radiobiology and Radiohygiene, Budapest, 1.09.2000, Budapest, Ungarn.

Influence on phagocytosis and free radical production in mouse macrophages following exposure to 50 Hz ELF-EMF as possible stimuli for cell activation? 22 Annual Meeting of The Bioelectromagnetics Society, 13.06.2000, München.

Biologische Wirkung elektromagnetischer Felder. Seminarreihe im Fachbereich Elektrotechnik und Informationstechnik (Prof. Dr. Ursula van Rienen) an der Universität Rostock, 26.05.2000, Rostock

Elektromagnetische Felder als Stressfaktoren. Tage der Forschung an der Universität Rostock, 11.11.1999, Rostock

Wirkung niederfrequenter elektromagnetische Felder auf die Phagocytose in murinen Knochenmarksmakrophagen. Tagung der Arbeitsgruppe elektromagnetische Felder, 5-6. 05. 1999, Dresden

Untersuchungen zur Mikrostrukturbildung und zur Induktion von programmiertem Zelltod nach Exposition mit 50 Hz-Feldern in vitro. 8.Arbeitssitzung - Biologische Wirkung elektromagnetischer Strahlung - Forschungsinitiative NRW - 19.11.1997, Essen

Biologische Wirkung elektromagnetischer Felder. Seminarreihe im Fachbereich Informatik (PD. Dr. Siegmar Adomßent) der Universität Rostock, März,1998, Rostock

Biologische Wirkung elektromagnetischer Felder. Tage der Forschung an der Universität Rostock, Nov. 1997, Rostock


Diploma thesis, Doctoral thesis, and Habilitation

Isolierung und Charakterisierung einer Elastase aus dem Hundepankreas. Diplomarbeit, Universität Giessen, 1986

Lokalisierung, Isolierung und Charakterisierung eines mit monoklonalen Antikörpern entdeckten Nicht-Histon-Proteins. Doktorarbeit, Universität Heidelberg, 1989

Extremely low frequency electromagnetic fields as effectors of cellular responses in vitro. A possible cell activation stimulus? Habilitation, Universität Rostock, 2001


Selected Abstracts (since 1999)

Frahm J, Hoffmann E, Hannemann S, Simkó M: Oscillation of coated-pit vesicle related proteins after magnetic field exposure to mouse macrophages Eur J Cell Biol 85, 26-26 Suppl. 56 (2006).

Simkó M, Frahm J, Lupke M and Maercker C: ELF-MF induce cell activation via the alternative pathway in immune relevant cells. 4th International Workshop on Biological Effects of Electromagnetic Fields. Crete, Greece, Proceedings (2006).

Simko M and Lantow M: Functional and molecular investigations after 1.8 GHz radiofrequency electromagnetic fiels exposure in different immune cells. Workshop "Proposed mechanisms for the interaction of RF-Signals with living Matter", Rostock, Germany Abstract Book, 15, (2006).

Lantow M, Hartwig C, Maercker C and Simkó M: Free radical Production, Hsp70 exression and protein profiling after 1800 mhz RF exposure in different immune relevant cells. 27 Annual Meeting of The BEMS, 2005, Dublin, Ireland Abstract Book (2005).

Lupke M, Rollwitz J, Lantow M, Maercker C and Simkó M: Activation of umbilical cord blood-derived monocytes following exposure to 50 Hz electromagnetic fields. 27 Annual Meeting of The BEMS, 2005, Dublin, Ireland Abstract Book (2005).

Simkó M and Mattsson MO: Induction of cell activation processes by low frequency electromagnetic fields. 27 Annual Meeting of The BEMS, 2005, Dublin, Ireland Abstract Book (2005).

HSP70 regulation in human cells after exposure to 50 Hz magnetic fields: Mannerling AC, Hannemann S, Simkó M, Hansson Mild K, Mattsson MO: 27 Annual Meeting of The BEMS, 2005, Dublin, Ireland Abstract Book (2005).

Lantow M and Simkó M: 1800 MHz RF-EMF do not induce free radical production in different immune relevant cells. 26 Annual Meeting of The BEMS, 2004, Washington DC, USA, Abstract Book, (2004).

Simkó M, Hannemann S and Lange S: Modifications in cell cycle kinetics and in expression of G1 phase-regulating proteins in human amniotic cells after exposure to 50 Hz electromagnetic fields and ionizing radiation. 26 Annual Meeting of The BEMS, 2004, Washington DC, USA, Abstract Book, (2004).

Lupke M, Maercker C and Simkó M: Alteration in gene expression after 50 Hz ELF-MF exposure in human umbilical cord blood-derived monocytes. Biological Effects of Electromagnetic Fields, 3nd International Workshop, Kos, Greece, Proceedings, (2004).

Simkó M, Lupke M and Rollwitz J: Cell activation processes induced by 50 Hz electromagnetic fields. 25 Annual Meeting of The BEMS, 2003, Maui, Hawaii, USA, Abstract Book, (2003).

Lupke M, Rollwitz J, Viergutz T and Simkó M: Activation of umbilical cord blood-derived monocytes following exposure to 50 Hz electromagnetic fields. 25 Annual Meeting of The BEMS, 2003, Maui, Hawaii, USA, Abstract Book, (2003).

Rollwitz J, Lupke M and Simkó M: The induction of cell activation processes after exposure to 50 Hz EMF is dependent on the differentiation status of mouse macrophages. 25 Annual Meeting of The BEMS, 2003, Maui, Hawaii, USA, Abstract Book, (2003).

M. Simkó and Lange S: Alterations in the expression level of cell cycle regulating proteins after exposure to 50 Hz electromagnetic fields in human cells. Biological Effects of Electromagnetic Fields, 2nd International Workshop, Rhodes, Greece, Proceedings, (2002).

Simkó M and Rollwitz J: Cell cycle disturbances, interleukin production and generation of superoxide radicals after exposure to 50 Hz EMF in mouse macrophages. 24 Annual Meeting of The BEMS, 2002, Quebec, Canada, Abstract Book, (2002)

Simkó M, Richard D, Kriehuber R and Weiss DG: Micronucleus induction in SHE cells following exposure to 50 Hz magnetic fields, Benzo(a)pyrene and TPA in vitro. 23 Annual Meeting of The BEMS, 2001, St. Paul, Minnesota, USA, Abstract Book, 73-74 (2001)

Kriehuber, R, Simkó M, Unverricht M, Lange S. Richard D, Weiss DG: Radiation-induced apoptosis in a tumour cell line lacking functional p53. In Proceedings of the 31st Annual Meeting of the European Society for Radiation Biology (ESBR) and 5. Jahrestagung der Gesellschaft für Biologische Strahlenforschung, Eds. W. Dörr, D. Frankenberg, D. Harder, J. Kiefer, 141 (2001)

Lange S, Richard D, Viergutz T, Kriehuber R, Weiss DG, Simkó M: Effects of 50 Hz magnetic fields and ionizing radiation on the cell cycle and on G1-phase regulating proteins in human cells. In Proceedings of the 31st Annual Meeting of the European Society for Radiation Biology (ESBR) and 5. Jahrestagung der Gesellschaft für Biologische Strahlenforschung, Edts. W. Dörr, D. Frankenberg, D. Harder, J. Kiefer, 202 (2001)

Lange S, Richard D, Viergutz T, Kriehuber R, and Simkó M: Analysis of the cell cycle and the expresssion of G1 regulating proteins after exposure to 50 Hz MF in human amniotic fluid cell. 23 Annual Meeting of The BEMS, 2001, St. Paul, Minnesota, USA, Abstract Book, 111-112 (2001)

Lange S, Richard D, Viergutz T, Kriehuber R, and Simkó M: Influence of 50 Hz electromagnetic fields in combination with ionizing radiation on the cell cycle progression and on proteins involved in G1/S transition in two human cell lines. Millennium Workshop on Biological Effects of Electromagnetic Fields, Heraklion, Greece, 2000

Simkó M, Droste S, Kriehuber R and Weiss DG: Influence on phagocytosis and free radical production in mouse macrophages following exposure to 50 Hz ELF-EMF as possible stimuli for cell activation? 22 Annual Meeting of The BEMS, 2000, Munich, Germany, Abstract Book, 5-4 (2000)

Richard D, Lange S, Viergutz T, Kriehuber R, Simkó M: The influence of 50 Hz EMF in combination with tumour promoting phorbol ester on protein kinase C and on cell cycle in two human cell lines. 22 Annual Meeting of The BEMS, 2000, Munich, Germany, Abstract Book, P-88 (2000)

Kriehuber R, Riedling M, Lange S, Richard D, Viergutz T, Weiss DG and Simkó M: Apoptosis in tumour cells lacking functional p53. Eur. J. Cell Biol. Suppl. (2000)

Kriehuber R and Simkó M: Induction of apoptosis, micronucleus formation and cell survival in SCL-II cells after exposure to auger electrons. 11th. International Congress of Radiation Research, Dublin, p 224 (1999)

Lange S, Richard D, Nebe B, Kriehuber R and Simkó M: Cell cycle disturbances after exposure to 50 Hz electromagnetic fields of human amniotic fluid cells. 11th. International Congress of Radiation Research, Dublin, p 221 (1999)

Kriehuber R, Weiss DG and Simkó M: Study on the induction of apoptosis, micronucleus formation and cell survival in SCL-II cells after exposure to the Auger electron emitter Zn-65. 4th International Symposium on Biophysical Aspects of Auger Processes, Lund University, Sweden, p. 37 (1999)

Droste S and Simkó M: Studies to the phagocytic activity, intracellular transport and free radical production in mouse bone marrow-derived macrophages after exposure to 50 Hz EMF. 21. Annual Meeting of The BEMS, Jun 1999, Long Beach, USA, Abstract Book, P-31 (1999)

Kriehuber R, Simkó M, Riedling M and Weiss DG: Studies on cell survival, induction of apoptosis and micronucleus formation in a human cell line after exposure to auger electrons and external radiation. Eur. J. Cell Biol. Suppl. 49, p278 (1999)

Lange S, Richard D, Nebe B, Kriehuber R, Weiss DG and Simkó M: Influence of 50 Hz Electromagnetic Fields on the Cell Cycle of Human Amniotic Fluid Cells. Eur. J. Cell Biol. Suppl. 49, p278 (1999)

Richard D, Lange S, Weiss DG and Simkó M: The influence of 50 Hz magnetic fields (MF) and phorbol ester on protein kinase C (PKC) in human amniotic fluid cells. Eur. J. Cell Biol. Suppl. 49, p277 (1999)

Droste S, Weiss DG and Simkó M: Influence on phagocytosis, intracellular transport, TPA-stimulation and free radical production in mouse bone marrow-derived macrophages after exposure to electromagnetic fields. Eur. J. Cell Biol. Suppl. 49, p275 (1999)