TY - JOUR AB - The phenomenon of molecular optical activity manifests itself as the rotation of the plane of linear polarization when light passes through chiral media. Measurements of optical activity and its wavelength dependence, that is, optical rotatory dispersion, can reveal information about intricate properties of molecules, such as the three-dimensional arrangement of atoms comprising a molecule. Given a limited probe power, quantum metrology offers the possibility of outperforming classical measurements. This has particular appeal when samples may be damaged by high power, which is a potential concern for chiroptical studies. We present the first experiment in which multiwavelength polarization-entangled photon pairs are used to measure the optical activity and optical rotatory dispersion exhibited by a solution of chiral molecules. Our work paves the way for quantum-enhanced measurements of chirality, with potential applications in chemistry, biology, materials science, and the pharmaceutical industry. The scheme that we use for probing wavelength dependence not only allows one to surpass the information extracted per photon in a classical measurement but also can be used for more general differential measurements. AU - Tischler, Nora AU - Krenn, Mario AU - Fickler, Robert AU - Vidal, Xavier AU - Zeilinger, Anton AU - Molina-Terriza, Gabriel DA - 2016/10/05/ DO - 10.1126/sciadv.1601306 IS - 10 JF - Science Advances PY - 2016 SE - 2016/10/05/ SP - 1601306 TI - Quantum optical rotatory dispersion UR - https://arxiv.org/pdf/1701.00944 UR - https://doi.org/10.1126/sciadv.1601306 VL - 2 ER -